Electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy (ePIPAC): Finding the optimal electrical potential

Mohammad Rahimi-Gorji, Charlotte Debbaut, Ghader Ghorbaniasl, Wouter Willaert, Sarah Cosyns, Wim Ceelen

Research output: Contribution to journalArticle

Abstract

Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is a therapy option for patients with peritoneal metastases. During PIPAC, a high-pressure injector delivers the drugs through a nebulizer into the peritoneal cavity. However, gravity typically causes inhomogeneous droplet distribution in the peritoneal space and may be overcome by the addition of an electrostatic force, resulting in electrostatic precipitation PIPAC (ePIPAC). Our goal was to find the optimal electrical potential for ePIPAC by means of in vitro experiments and numerical modeling.
Original languageEnglish
Article numbere30
JournalEuropean Journal of Surgical Oncology
Volume47
Issue number2
Publication statusPublished - Feb 2021

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