Feasibility of image-guided radiotherapy for cardiac sparing in patients with left-sided breast cancer

The International Geriatric Radiotherapy Group

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Patients with left-sided breast cancer are at risk of cardiac toxicity because of cardiac irradiation during radiotherapy with the conventional 3-dimensional conformal technique (3D-CRT). In addition, many patients may receive chemotherapy prior to radiation which may damage the myocardium and may increase the potential for late cardiac complications. New radiotherapy techniques such as intensity-modulated radiotherapy (IMRT) may decrease the risk of cardiac toxicity because of the steep dose gradient limiting the volume of the heart irradiated to a high dose. Image-guided radiotherapy (IGRT) is a new technique of IMRT delivery with daily imaging which may further reduce excessive cardiac irradiation. Preliminary results of IGRT for cardiac sparing in patients with left-sided breast cancer are promising and need to be investigated in future prospective clinical studies.

Original languageEnglish
Article number257
Number of pages4
JournalFrontiers in Oncology
Volume4
Issue numberSEP
DOIs
Publication statusPublished - 1 Jan 2014

Keywords

  • Breast cancer
  • Cardiac toxicity
  • IGRT
  • Left breast

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