Fractional frequency domain identification of NaCl–glucose solutions at physiological levels

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6 Citations (Scopus)


Electrical impedance spectroscopy (EIS) has been used to characterize different biological materials. This article exposes a methodology oriented to estimate glucose levels of a solution based on a rational fractional parametric model of the impedance data. The methodology is applied over saline-glucose solutions at five physiological glucose levels, using three sensors and five repetitions for each glucose concentration and employed sensor. The results suggest that changes in the glucose concentration produce significant changes in the impedance that should be reflected in the parametric model. The modeling procedure shows that the poles and zeros of an integer model presents a degree of correlation. However, the correlation is clearly explicit employing fractional models where the mean location of the complex zeros is highly related to the glucose content in the sample.
Original languageEnglish
Pages (from-to)213-221
Number of pages9
Publication statusPublished - 1 Apr 2014


  • Impedance spectroscopy
  • Odd random phase multisine
  • Glucose sensor
  • Best linear approximation
  • Parametric model
  • Nonparametric model
  • Fractional model
  • Rational model


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