High-performance liquid chromatography with a controllable transverse flow inducer

A chromatographic column assembly (2) is described, comprising a channel (12) and a flow inducer (5). The channel (12) comprises an inlet (13) for receiving a sample liquid and an outlet (14), and is adapted for separating the sample liquid into components when the sample liquid flows through the channel in an axial direction from the inlet to the outlet. The flow inducer (5) is adapted for controllably inducing, when the sample fluid is flowing through the channel, a motion (19) of the sample liquid in the channel in a plane substantially orthogonal to the axial direction (A).