Hormonal changes during a spontaneous attack of hypokalemic periodic paralysis

Jacques De Keyser, Ronald Malfait, A. Van Steirteghem, Guy Ebinger, J. Smitz

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We studied the hormonal changes during a spontaneous attack of hypokalemic periodic paralysis in a 20-year-old man, before and after treatment with potassium chloride. During paralysis, we observed high circulating levels of insulin, epinephrine, norepinephrine, growth hormone, ACTH and cortisol, most likely reflecting a condition of stress. Normalization of all these hormones occurred with recovery. Plasma aldosterone concentrations were normal. The increased plasma levels of insulin, but also of catecholamines and growth hormone, created a condition promoting potassium uptake in muscle cells. We suggest that stress may play a role in the pathophysiology of the paralytic attacks in this disorder.
Original languageEnglish
Pages (from-to)60-64
Number of pages5
JournalEur Neurol
Volume26
Publication statusPublished - 1987

Keywords

  • Adult
  • Case Report
  • Catecholamines/blood
  • Corticotropin/blood
  • Hormones/*blood
  • Human
  • Hydrocortisone/blood
  • Hypokalemia/*blood/complications
  • Insulin/blood
  • Male
  • Paralysis/blood/*etiology
  • Periodicity

Fingerprint

Dive into the research topics of 'Hormonal changes during a spontaneous attack of hypokalemic periodic paralysis'. Together they form a unique fingerprint.

Cite this