Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease

Alexandra Gatzios; Robim Rodrigues; Joery De Kock; Matthias Rombaut; Dinja De Win; Vera Rogiers; Joost Boeckmans; Tamara Vanhaecke

doi:10.1016/S0168-8278(23)00435-X

Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease

Alexandra Gatzios, Robim Rodrigues, Joery De Kock, Matthias Rombaut, Dinja De Win, Vera Rogiers, Joost Boeckmans, Tamara Vanhaecke

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)

9 Downloads (Pure)

Original language	English
Title of host publication	Abstract Book of EASL Congress 2023
Subtitle of host publication	21-24 June 2023, Vienna, Austria
Publisher	Elsevier
Pages	S775-S776
Number of pages	2
Volume	78(S1)
DOIs	https://doi.org/10.1016/S0168-8278(23)00435-X
Publication status	Published - Jun 2023
Event	EASL Congress 2023 - Vienna, Austria Duration: 21 Jun 2023 → 24 Jun 2023 https://www.easlcongress.eu/

Publication series

Name	Poster presentations
Publisher	Elsevier
Volume	78(S1)
ISSN (Print)	0168-8278
ISSN (Electronic)	0168-8278

Conference

Conference	EASL Congress 2023
Country/Territory	Austria
City	Vienna
Period	21/06/23 → 24/06/23
Internet address	https://www.easlcongress.eu/

Keywords

MAFLD
in vitro
pharmacogenetics
polygenic risk score

Access to Document

10.1016/S0168-8278(23)00435-X

Journal of Hepatology - Abstract Book of EASL Congress 2023

1 Active

FWOSB134: Development and application of a human stem cell-derived, etiology-based anti-MAFLD drug discovery platform targeting the thyroid hormone receptor axis
Vanhaecke, T., Boeckmans, J., Marcelino Rodrigues, R. & Gatzios, A.
1/11/22 → 31/10/26
Project: Fundamental

1 Poster

Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease
Gatzios, A., Rodrigues, R., De Kock, J., Rombaut, M., De Win, D., Rogiers, V., Boeckmans, J. & Vanhaecke, T., 21 Jun 2023.
Research output: Unpublished contribution to conference › Poster

Colgate-Palmolive postdoctoral fellowship award in in vitro toxicology
Boeckmans, Joost (Recipient), 19 Mar 2023
Prize: Prize (including medals and awards)

Cite this

Gatzios, A., Rodrigues, R., De Kock, J., Rombaut, M., De Win, D., Rogiers, V., Boeckmans, J., & Vanhaecke, T. (2023). Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease. In Abstract Book of EASL Congress 2023: 21-24 June 2023, Vienna, Austria (Vol. 78(S1), pp. S775-S776). [WED-465] (Poster presentations; Vol. 78(S1)). Elsevier. https://doi.org/10.1016/S0168-8278(23)00435-X

Gatzios, Alexandra ; Rodrigues, Robim ; De Kock, Joery ; Rombaut, Matthias ; De Win, Dinja ; Rogiers, Vera ; Boeckmans, Joost ; Vanhaecke, Tamara. / Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease. Abstract Book of EASL Congress 2023: 21-24 June 2023, Vienna, Austria. Vol. 78(S1) Elsevier, 2023. pp. S775-S776 (Poster presentations).

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title = "Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease",

keywords = "MAFLD, in vitro, pharmacogenetics, polygenic risk score",

author = "Alexandra Gatzios and Robim Rodrigues and {De Kock}, Joery and Matthias Rombaut and {De Win}, Dinja and Vera Rogiers and Joost Boeckmans and Tamara Vanhaecke",

year = "2023",

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Gatzios, A , Rodrigues, R , De Kock, J , Rombaut, M , De Win, D , Rogiers, V , Boeckmans, J & Vanhaecke, T 2023, Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease. in Abstract Book of EASL Congress 2023: 21-24 June 2023, Vienna, Austria. vol. 78(S1), WED-465, Poster presentations, vol. 78(S1), Elsevier, pp. S775-S776, EASL Congress 2023, Vienna, Austria, 21/06/23. https://doi.org/10.1016/S0168-8278(23)00435-X

Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease. / Gatzios, Alexandra ; Rodrigues, Robim ; De Kock, Joery ; Rombaut, Matthias ; De Win, Dinja ; Rogiers, Vera ; Boeckmans, Joost ; Vanhaecke, Tamara.

Abstract Book of EASL Congress 2023: 21-24 June 2023, Vienna, Austria. Vol. 78(S1) Elsevier, 2023. p. S775-S776 WED-465 (Poster presentations; Vol. 78(S1)).

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)

TY - CHAP

T1 - Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease

AU - Gatzios, Alexandra

AU - Rodrigues, Robim

AU - De Kock, Joery

AU - Rombaut, Matthias

AU - De Win, Dinja

AU - Rogiers, Vera

AU - Boeckmans, Joost

AU - Vanhaecke, Tamara

PY - 2023/6

Y1 - 2023/6

KW - MAFLD

KW - in vitro

KW - pharmacogenetics

KW - polygenic risk score

U2 - 10.1016/S0168-8278(23)00435-X

DO - 10.1016/S0168-8278(23)00435-X

M3 - Meeting abstract (Book)

VL - 78(S1)

T3 - Poster presentations

SP - S775-S776

BT - Abstract Book of EASL Congress 2023

PB - Elsevier

Y2 - 21 June 2023 through 24 June 2023

ER -

Gatzios A , Rodrigues R , De Kock J , Rombaut M , De Win D , Rogiers V et al. Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease. In Abstract Book of EASL Congress 2023: 21-24 June 2023, Vienna, Austria. Vol. 78(S1). Elsevier. 2023. p. S775-S776. WED-465. (Poster presentations). https://doi.org/10.1016/S0168-8278(23)00435-X

Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease

Publication series

Conference

Keywords

Access to Document

Projects

FWOSB134: Development and application of a human stem cell-derived, etiology-based anti-MAFLD drug discovery platform targeting the thyroid hormone receptor axis

Research output

Human skin stem cell-derived hepatic cells with genetic predisposition for liver fat accumulation mimic susceptibility to develop metabolic dysfunction-associated fatty liver disease

Prizes

Colgate-Palmolive postdoctoral fellowship award in in vitro toxicology

Cite this