IMMUNOGOLD-SILVER STAINING OF CELLS RECOVERED BY BRONCHOALVEOLAR LAVAGE - A REPORT OF 3 CASES DEMONSTRATING ITS VALUE IN THE DIAGNOSIS OF PULMONARY INVOLVEMENT IN HEMATOLOGIC MALIGNANCIES

Marc Noppen, Walter Vincken, H. Slabbynck, M. De Waele, P. Lacor, I. Monsieur

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: The diagnosis of pulmonary involvement ment in hematologic malignancies (PHM) has traditionally necessitated large specimens (usually invasive or surgically obtained biopsies). The development of reliable immunocytologic identification techniques allows diagnosis on noninvasively obtained cellular material, including bronchoalveolar lavage (BAL) fluid. Since 1985, 12 such cases have been reported.
CASES: Three cases of B-cell-related PHM were diagnosed by means of BAL fluid cellular analysis using the immunogold-silver staining technique.

CONCLUSION: This is the first report showing immunogold-silver staining to be a reliable immunocytochemical identification technique for monoclonal B-cell populations recovered by BAL.
Original languageEnglish
Pages (from-to)1141-1147
Number of pages7
JournalACTA CYTOLOGICA
Volume39
Issue number6
Publication statusPublished - Nov 1995

Keywords

  • NON-HODGKINS LYMPHOMA; SURFACE ANTIGENS; LEUKEMIA;

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