Impact of Plaque Components on Fractional Flow Reserve-Derived Computed Tomography in Severe Coronary Stenosis

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Abstract

Fractional flow reserve derived from computed tomography decreases across severe coronary stenosis. The diagnostic accuracy of fractional flow reserve-derived computed tomography is high for severe coronary stenosis. In this report, we present a case of no significant fractional flow reserve-derived computed tomography changes even in severe coronary stenosis. A 75-year-old man showed severe stenosis (85% diameter stenosis) in the distal segment of the right coronary artery on both computed tomography angiography and invasive coronary angiography. However, fractional flow reserve-derived from computed tomography showed no significant changes from the proximal (0.97) to the distal (0.95) segments despite the presence of severe stenotic lesion. This patient had different features including the presence of a large acute marginal branch and significantly lower plaque components in the stenotic lesion compared with another patient who had coronary stenosis in the same segment. A large bifurcation branch and/or proportion of plaque components can affect fractional flow reserve-derived from computed tomography hemodynamics.

Original languageEnglish
Pages (from-to)356-360
Number of pages5
JournalTürk Kardiyoloji Dernegi Arşivi
Volume51
Issue number5
DOIs
Publication statusPublished - Jul 2023

Bibliographical note

Cite this article as: Tsugu T, Tanaka K,
Nagatomo Y, De Maeseneer M,
De Mey J. Impact of plaque components
on fractional flow reserve-derived
computed tomography in severe
coronary stenosis. Turk Kardiyol Dern Ars.
2023;51(5):356-360.

Keywords

  • computed tomography
  • fractional flow reverse
  • imaging

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