Impact of prosthesis-patient mismatch on mitral regurgitation after aortic valve replacement

Ph. Unger, J. Magne, F. Vanden Eynden, D. Plein, Guy Van Camp, A. Pasquet, Bernard Cosyns, C. Dedobbeleer, P. Lancellotti

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Background Mitral regurgitation is frequently observed in patients undergoing aortic valve replacement (AVR) for aortic stenosis and often improves postoperatively, mainly due to left ventricular remodelling and changes in loading conditions. Aortic prosthesis-patient mismatch (PPM) is associated with poor outcome and lesser left ventricular remodelling. This study tested the hypothesis that aortic PPM affects mitral regurgitation.
Methods and results Echocardiography was performed preoperatively and before discharge in 42 patients with aortic stenosis undergoing isolated AVR and presenting mitral regurgitation with an effective regurgitant orifice (ERO) of 10 mm(2) or greater, as assessed by the proximal isovelocity surface area method. Postoperatively, mitral ERO and the regurgitant volume decreased from 16 +/- 5 mm(2) to 12 +/- 6 mm(2) (p
Conclusions The presence of PPM after AVR attenuates postoperative mitral regurgitation changes, mainly in patients with organic mitral regurgitation.
Original languageEnglish
Pages (from-to)1627-1632
Number of pages6
JournalHeart
Volume96
Issue number20
Publication statusPublished - Oct 2010

Keywords

  • LEFT-VENTRICULAR DYSFUNCTION
  • HEART-FAILURE
  • STENOSIS
  • REPAIR
  • IMPROVEMENT
  • MANAGEMENT
  • SEVERITY
  • SURVIVAL
  • EXERCISE

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