Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction.

Miriam Shanks; Arnold Ng; Nico Van De Veire; Louisa Antoni; Matteo Bertini; Victoria Delgado; Gaetano Nucifora; Eduard Holman; J Choy; Dominic Leung; Martin Schalij; Jeroen Bax

Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction.

Miriam Shanks, Arnold Ng, Nico Van De Veire, Louisa Antoni, Matteo Bertini, Victoria Delgado, Gaetano Nucifora, Eduard Holman, J Choy, Dominic Leung, Martin Schalij, Jeroen Bax

Cardio-vascular diseases

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

This study examined the prognostic value of novel diastolic indexes in ST-elevation acute myocardial infarction (AMI), derived from strain and strain rate analysis using 2-dimensional speckle tracking imaging. Echocardiograms were obtained within 48 hours of admission in 371 consecutive patients with first ST-elevation AMI (59.7 +/- 11.6 years old). Indexes of diastolic function including mean strain rate during isovolumic relaxation (SR(IVR)), mean early diastolic strain rate (SR(E)) and mean diastolic strain at peak transmitral E wave (E) were obtained from 3 apical views. Mean early diastolic velocity from 4 basal segments by color-coded tissue Doppler imaging was measured. Indexes of diastolic filling including E/SR(IVR), E/SR(E), E/diastolic strain at E, and E/early diastolic velocity were calculated. The primary end point (composite of death, hospitalization for heart failure, repeat MI, and repeat revascularization) occurred in 84 patients (22.6%) during a mean follow-up of 17.3 +/- 12.2 months. Mean SR(IVR) (p

Original language	English
Pages (from-to)	592-597
Number of pages	6
Journal	The American Journal of Cardiology
Volume	105
Issue number	5
Publication status	Published - 1 Mar 2010

Keywords

diastolic function
FILLING PRESSURE
DOPPLER-ECHOCARDIOGRAPHY
STRAIN-RATE

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Shanks, Miriam ; Ng, Arnold ; Van De Veire, Nico ; Antoni, Louisa ; Bertini, Matteo ; Delgado, Victoria ; Nucifora, Gaetano ; Holman, Eduard ; Choy, J ; Leung, Dominic ; Schalij, Martin ; Bax, Jeroen. / Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction. In: The American Journal of Cardiology. 2010 ; Vol. 105, No. 5. pp. 592-597.

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title = "Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction.",

abstract = "This study examined the prognostic value of novel diastolic indexes in ST-elevation acute myocardial infarction (AMI), derived from strain and strain rate analysis using 2-dimensional speckle tracking imaging. Echocardiograms were obtained within 48 hours of admission in 371 consecutive patients with first ST-elevation AMI (59.7 +/- 11.6 years old). Indexes of diastolic function including mean strain rate during isovolumic relaxation (SR(IVR)), mean early diastolic strain rate (SR(E)) and mean diastolic strain at peak transmitral E wave (E) were obtained from 3 apical views. Mean early diastolic velocity from 4 basal segments by color-coded tissue Doppler imaging was measured. Indexes of diastolic filling including E/SR(IVR), E/SR(E), E/diastolic strain at E, and E/early diastolic velocity were calculated. The primary end point (composite of death, hospitalization for heart failure, repeat MI, and repeat revascularization) occurred in 84 patients (22.6%) during a mean follow-up of 17.3 +/- 12.2 months. Mean SR(IVR) (p",

keywords = "diastolic function, FILLING PRESSURE, DOPPLER-ECHOCARDIOGRAPHY, STRAIN-RATE",

author = "Miriam Shanks and Arnold Ng and {Van De Veire}, Nico and Louisa Antoni and Matteo Bertini and Victoria Delgado and Gaetano Nucifora and Eduard Holman and J Choy and Dominic Leung and Martin Schalij and Jeroen Bax",

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Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction. / Shanks, Miriam; Ng, Arnold; Van De Veire, Nico; Antoni, Louisa; Bertini, Matteo; Delgado, Victoria; Nucifora, Gaetano; Holman, Eduard; Choy, J; Leung, Dominic; Schalij, Martin; Bax, Jeroen.

In: The American Journal of Cardiology, Vol. 105, No. 5, 01.03.2010, p. 592-597.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction.

AU - Shanks, Miriam

AU - Ng, Arnold

AU - Van De Veire, Nico

AU - Antoni, Louisa

AU - Bertini, Matteo

AU - Delgado, Victoria

AU - Nucifora, Gaetano

AU - Holman, Eduard

AU - Choy, J

AU - Leung, Dominic

AU - Schalij, Martin

AU - Bax, Jeroen

PY - 2010/3/1

Y1 - 2010/3/1

N2 - This study examined the prognostic value of novel diastolic indexes in ST-elevation acute myocardial infarction (AMI), derived from strain and strain rate analysis using 2-dimensional speckle tracking imaging. Echocardiograms were obtained within 48 hours of admission in 371 consecutive patients with first ST-elevation AMI (59.7 +/- 11.6 years old). Indexes of diastolic function including mean strain rate during isovolumic relaxation (SR(IVR)), mean early diastolic strain rate (SR(E)) and mean diastolic strain at peak transmitral E wave (E) were obtained from 3 apical views. Mean early diastolic velocity from 4 basal segments by color-coded tissue Doppler imaging was measured. Indexes of diastolic filling including E/SR(IVR), E/SR(E), E/diastolic strain at E, and E/early diastolic velocity were calculated. The primary end point (composite of death, hospitalization for heart failure, repeat MI, and repeat revascularization) occurred in 84 patients (22.6%) during a mean follow-up of 17.3 +/- 12.2 months. Mean SR(IVR) (p

AB - This study examined the prognostic value of novel diastolic indexes in ST-elevation acute myocardial infarction (AMI), derived from strain and strain rate analysis using 2-dimensional speckle tracking imaging. Echocardiograms were obtained within 48 hours of admission in 371 consecutive patients with first ST-elevation AMI (59.7 +/- 11.6 years old). Indexes of diastolic function including mean strain rate during isovolumic relaxation (SR(IVR)), mean early diastolic strain rate (SR(E)) and mean diastolic strain at peak transmitral E wave (E) were obtained from 3 apical views. Mean early diastolic velocity from 4 basal segments by color-coded tissue Doppler imaging was measured. Indexes of diastolic filling including E/SR(IVR), E/SR(E), E/diastolic strain at E, and E/early diastolic velocity were calculated. The primary end point (composite of death, hospitalization for heart failure, repeat MI, and repeat revascularization) occurred in 84 patients (22.6%) during a mean follow-up of 17.3 +/- 12.2 months. Mean SR(IVR) (p

KW - diastolic function

KW - FILLING PRESSURE

KW - DOPPLER-ECHOCARDIOGRAPHY

KW - STRAIN-RATE

M3 - Article

VL - 105

SP - 592

EP - 597

JO - The American Journal of Cardiology

JF - The American Journal of Cardiology

SN - 0002-9149

IS - 5

ER -

Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction.

Abstract

Keywords

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