Abstract
Microarray technology has become an integral part of biomedical research and increasing amounts of datasets become available through public repositories. However, re-use of these datasets is severely hindered by unstructured, missing, or incorrect biological samples information; as well as the wide variety of preprocessing methods in use. The inSilicoDb RBioconductor package is a command-line front-end to the InSilico DB, a web- based database currently containing 86,104 expert-curated human Affymetrix expression profiles compiled from 1,937 GEO repository series. The use of this package builds on the Bioconductor project's focus on reproducibility by enabling a clear workflow in which not only analysis, but also the retrieval of verified data, is supported.
Original language | English |
---|---|
Pages (from-to) | 3204-3205 |
Number of pages | 2 |
Journal | Bioinformatics |
Volume | 22 |
Issue number | 27 |
Publication status | Published - 2011 |
Keywords
- microarray data