Intravascular ultrasound comparison of Sirolimus-eluting stent versus bare metal stent implantation in diseased saphenous vein grafts (from the RRISC [Reduction of restenosis in saphenous vein grafts with cypher sirolimus-eluting stent] trial)

P. Agostoni, Paul Vermeersch, Oscar Semeraro Salabert

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

The randomized Reduction of Restenosis In Saphenous Vein Grafts with Cypher Sirolimus-Eluting Stent trial compared angiographic outcomes of sirolimus-eluting stents (SESs) versus bare metal stents (BMSs) in saphenous vein grafts (SVG). Using intravascular ultrasound (IVUS) performed during 6-month follow-up angiography, we compared the vascular effects of the 2 types of stent on SVGs. of 75 patients (96 lesions) included, 59 patients underwent IVUS in 61 SVGs; 29 patients received 40 SESs for 34 lesions, and 30 patients received 42 BMSs for 39 lesions. IVUS parameters (diameters, areas, and volumes) were compared in the 2 groups. A specific analysis was performed for overlapping SESs. Median neointimal volume was 1.3 mm(3) (interquartile range 0 to 13.1) in SESs versus 24.5 (7.8 to 39.5) in BMSs (p
Original languageEnglish
Pages (from-to)52-58
Number of pages7
JournalThe American Journal of Cardiology
Volume100
Issue number1
Publication statusPublished - 1 Jul 2007

Keywords

  • DIABETIC-PATIENTS
  • BYPASS GRAFTS
  • DIMENSIONS
  • LUMEN

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