IS POSTOPERATIVE FATIGUE RELATED TO IMPAIRED MUSCLE ENDURANCE?

Ivan Bautmans, Rose Njemini, Bert Jansen, Jacques De Backer, Elisabeth De Waele, Tony Mets

Research output: Chapter in Book/Report/Conference proceedingMeeting abstract (Book)Research

Abstract

AIM
To investigate the relationship of post-operative fatigue with muscle endurance and circulating inflammatory cytokines.

METHODS
Prospective study including 84 patients (41 female and 43 male, age 24-91 years) scheduled for elective abdominal surgery (42 open and 42 laparoscopic). All patients were assessed one day before and 2 days after surgery; and if still hospitalized at day 4 (N=78) and day 7 (N=50) post-surgery. Outcome measures were self-perceived fatigue (Profile of Mood State), Fatigue Resistance (FR, time during which grip strength drops to 50% of its maximum), Grip Work (GW, work output delivered by the muscles during the FR-test), VAS for Pain and circulating Interleukin (IL)-6 and Tumor Necrosis Factor (TNF)-alpha. Data were analyzed using ANOVA for Repeated Measures, and correlations for changes over time were computed between perceived fatigue and the other outcome parameters.

RESULTS
All outcome-parameters worsened significantly (p75), patients aged >75 years worsened significantly more and recovered significantly less rapidly for FR at day4 post-surgery compared to the younger patients (p
CONCLUSION
Post-operative fatigue is related to reduced muscle endurance and elevated IL-6. Elderly patients show a higher impact of surgery on muscle endurance.
Original languageEnglish
Title of host publication5th Congress of the European Union geriatric Medicine Society, 3-6 september 2008, Copenhagen, Denmark
Publication statusPublished - Sep 2008
EventFinds and Results from the Swedish Cyprus Expedition: A Gender Perspective at the Medelhavsmuseet - Stockholm, Sweden
Duration: 21 Sep 200925 Sep 2009

Conference

ConferenceFinds and Results from the Swedish Cyprus Expedition: A Gender Perspective at the Medelhavsmuseet
CountrySweden
CityStockholm
Period21/09/0925/09/09

Keywords

  • Elderly
  • Frailty
  • Muscle fatigue
  • Postoperative fatigue
  • Inflammation
  • Cytokines
  • Fatigue resistance
  • Surgery

Fingerprint Dive into the research topics of 'IS POSTOPERATIVE FATIGUE RELATED TO IMPAIRED MUSCLE ENDURANCE?'. Together they form a unique fingerprint.

Cite this