Abstract
TPMT deficiency is associated with azathioprine (AZA)-induced myelosuppression (MS). However, in one previous study, only about ¼ of MS episodes in Crohn's Disease patients under AZA can be attributed to TPMT deficiency. Recently, new TPMT mutations have been described and our aim is to investigate their clinical relevance before and after a first MS episode on thiopurine therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 1062-1066 |
| Number of pages | 5 |
| Journal | Clinical Biochemistry |
| Volume | 13 |
| Issue number | 14 |
| Publication status | Published - Sept 2011 |
Keywords
- TPMT deficiency
- myelosuppression