Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion.

Mieke Cannie; A.g. Cordier; J. De Laveaucoupet; S. Franchi-Abella; M. Cagneaux; O. Prodhomme; M.v. Senat; M. Mokhtari; V. Vlieghe; D. Nowakowska; A. Benachi; J. Jani

Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion.

Mieke Cannie, A.g. Cordier, J. De Laveaucoupet, S. Franchi-Abella, M. Cagneaux, O. Prodhomme, M.v. Senat, M. Mokhtari, V. Vlieghe, D. Nowakowska, A. Benachi, J. Jani

Medical Imaging and Physical Sciences

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

To evaluate the relationship of the liver-to-thoracic volume ratio (LiTR) by MRI with postnatal survival in foetuses with isolated congenital diaphragmatic hernia (CDH).

In 30 conservatively managed CDH foetuses and in 31 who underwent fetoscopic endoluminal tracheal occlusion (FETO), logistic regression analysis was used to investigate the effect on postnatal survival of the observed-to-expected (O/E) ratio of total foetal lung volume (TFLV), LiTR, gestational age at delivery, CDH side, intrathoracic position of the liver and, for those who underwent FETO, gestational age at FETO and occlusion period. For 19 foetuses undergoing FETO, a post-FETO MRI was available. The proportionate increase in O/E ratio of TFLV at 3-8 weeks after FETO was compared with the pre-FETO value and correlated with pre-FETO LiTR using linear regression analysis.

For conservatively managed foetuses, only LiTR provided a significant prediction of postnatal survival. For foetuses undergoing FETO, LiTR and gestational age at delivery provided a significant independent prediction of postnatal survival. There was a significant inverse association between lung response and pre-FETO LiTR.

In foetuses with CDH with/without FETO treatment, the LiTR is predictive of postnatal survival at discharge. In foetuses treated with FETO, LiTR is predictive of post-FETO lung response.

aEuro cent Congenital diaphragmatic hernia is usually managed conservatively before surgery soon after delivery

aEuro cent Fetoscopic endoluminal tracheal occlusion (FETO) has been introduced for severely affected foetuses

aEuro cent In conservatively managed CDH, the liver-to-thoracic volume ratio (LiTR) predicted postnatal survival best.

aEuro cent In severe CDH with prenatal FETO, LiTR also helped predict postnatal survival.

aEuro cent LiTR should be integrated into the prenatal decision-making for foetuses with CDH

Original language	English
Pages (from-to)	1299-1305
Number of pages	7
Journal	Eur Radiol
Volume	23
Issue number	May
Publication status	Published - 2013

Keywords

Liver-to-thoracic volume ratio
Diaphragmatic hernia
Magnetic resonance imaging
Tracheal occlusion
Lung response

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http://www.ncbi.nlm.nih.gov/pubmed/23242000

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Cannie, M., Cordier, A. G., De Laveaucoupet, J., Franchi-Abella, S., Cagneaux, M., Prodhomme, O., Senat, M. V., Mokhtari, M., Vlieghe, V., Nowakowska, D., Benachi, A., & Jani, J. (2013). Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion. Eur Radiol, 23(May), 1299-1305. http://www.ncbi.nlm.nih.gov/pubmed/23242000

Cannie, Mieke ; Cordier, A.g. ; De Laveaucoupet, J. ; Franchi-Abella, S. ; Cagneaux, M. ; Prodhomme, O. ; Senat, M.v. ; Mokhtari, M. ; Vlieghe, V. ; Nowakowska, D. ; Benachi, A. ; Jani, J. / Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion. In: Eur Radiol. 2013 ; Vol. 23, No. May. pp. 1299-1305.

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title = "Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion.",

abstract = "To evaluate the relationship of the liver-to-thoracic volume ratio (LiTR) by MRI with postnatal survival in foetuses with isolated congenital diaphragmatic hernia (CDH). In 30 conservatively managed CDH foetuses and in 31 who underwent fetoscopic endoluminal tracheal occlusion (FETO), logistic regression analysis was used to investigate the effect on postnatal survival of the observed-to-expected (O/E) ratio of total foetal lung volume (TFLV), LiTR, gestational age at delivery, CDH side, intrathoracic position of the liver and, for those who underwent FETO, gestational age at FETO and occlusion period. For 19 foetuses undergoing FETO, a post-FETO MRI was available. The proportionate increase in O/E ratio of TFLV at 3-8 weeks after FETO was compared with the pre-FETO value and correlated with pre-FETO LiTR using linear regression analysis. For conservatively managed foetuses, only LiTR provided a significant prediction of postnatal survival. For foetuses undergoing FETO, LiTR and gestational age at delivery provided a significant independent prediction of postnatal survival. There was a significant inverse association between lung response and pre-FETO LiTR. In foetuses with CDH with/without FETO treatment, the LiTR is predictive of postnatal survival at discharge. In foetuses treated with FETO, LiTR is predictive of post-FETO lung response. aEuro cent Congenital diaphragmatic hernia is usually managed conservatively before surgery soon after delivery aEuro cent Fetoscopic endoluminal tracheal occlusion (FETO) has been introduced for severely affected foetuses aEuro cent In conservatively managed CDH, the liver-to-thoracic volume ratio (LiTR) predicted postnatal survival best. aEuro cent In severe CDH with prenatal FETO, LiTR also helped predict postnatal survival. aEuro cent LiTR should be integrated into the prenatal decision-making for foetuses with CDH",

keywords = "Liver-to-thoracic volume ratio, Diaphragmatic hernia, Magnetic resonance imaging, Tracheal occlusion, Lung response",

author = "Mieke Cannie and A.g. Cordier and {De Laveaucoupet}, J. and S. Franchi-Abella and M. Cagneaux and O. Prodhomme and M.v. Senat and M. Mokhtari and V. Vlieghe and D. Nowakowska and A. Benachi and J. Jani",

year = "2013",

language = "English",

volume = "23",

pages = "1299--1305",

journal = "European Radiology",

issn = "0938-7994",

publisher = "Springer Verlag",

number = "May",

}

Cannie, M, Cordier, AG, De Laveaucoupet, J, Franchi-Abella, S, Cagneaux, M, Prodhomme, O, Senat, MV, Mokhtari, M, Vlieghe, V, Nowakowska, D, Benachi, A & Jani, J 2013, 'Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion.', Eur Radiol, vol. 23, no. May, pp. 1299-1305. <http://www.ncbi.nlm.nih.gov/pubmed/23242000>

Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion. / Cannie, Mieke; Cordier, A.g.; De Laveaucoupet, J.; Franchi-Abella, S.; Cagneaux, M.; Prodhomme, O.; Senat, M.v.; Mokhtari, M.; Vlieghe, V.; Nowakowska, D.; Benachi, A.; Jani, J.

In: Eur Radiol, Vol. 23, No. May, 2013, p. 1299-1305.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion.

AU - Cannie, Mieke

AU - Cordier, A.g.

AU - De Laveaucoupet, J.

AU - Franchi-Abella, S.

AU - Cagneaux, M.

AU - Prodhomme, O.

AU - Senat, M.v.

AU - Mokhtari, M.

AU - Vlieghe, V.

AU - Nowakowska, D.

AU - Benachi, A.

AU - Jani, J.

PY - 2013

Y1 - 2013

N2 - To evaluate the relationship of the liver-to-thoracic volume ratio (LiTR) by MRI with postnatal survival in foetuses with isolated congenital diaphragmatic hernia (CDH). In 30 conservatively managed CDH foetuses and in 31 who underwent fetoscopic endoluminal tracheal occlusion (FETO), logistic regression analysis was used to investigate the effect on postnatal survival of the observed-to-expected (O/E) ratio of total foetal lung volume (TFLV), LiTR, gestational age at delivery, CDH side, intrathoracic position of the liver and, for those who underwent FETO, gestational age at FETO and occlusion period. For 19 foetuses undergoing FETO, a post-FETO MRI was available. The proportionate increase in O/E ratio of TFLV at 3-8 weeks after FETO was compared with the pre-FETO value and correlated with pre-FETO LiTR using linear regression analysis. For conservatively managed foetuses, only LiTR provided a significant prediction of postnatal survival. For foetuses undergoing FETO, LiTR and gestational age at delivery provided a significant independent prediction of postnatal survival. There was a significant inverse association between lung response and pre-FETO LiTR. In foetuses with CDH with/without FETO treatment, the LiTR is predictive of postnatal survival at discharge. In foetuses treated with FETO, LiTR is predictive of post-FETO lung response. aEuro cent Congenital diaphragmatic hernia is usually managed conservatively before surgery soon after delivery aEuro cent Fetoscopic endoluminal tracheal occlusion (FETO) has been introduced for severely affected foetuses aEuro cent In conservatively managed CDH, the liver-to-thoracic volume ratio (LiTR) predicted postnatal survival best. aEuro cent In severe CDH with prenatal FETO, LiTR also helped predict postnatal survival. aEuro cent LiTR should be integrated into the prenatal decision-making for foetuses with CDH

AB - To evaluate the relationship of the liver-to-thoracic volume ratio (LiTR) by MRI with postnatal survival in foetuses with isolated congenital diaphragmatic hernia (CDH). In 30 conservatively managed CDH foetuses and in 31 who underwent fetoscopic endoluminal tracheal occlusion (FETO), logistic regression analysis was used to investigate the effect on postnatal survival of the observed-to-expected (O/E) ratio of total foetal lung volume (TFLV), LiTR, gestational age at delivery, CDH side, intrathoracic position of the liver and, for those who underwent FETO, gestational age at FETO and occlusion period. For 19 foetuses undergoing FETO, a post-FETO MRI was available. The proportionate increase in O/E ratio of TFLV at 3-8 weeks after FETO was compared with the pre-FETO value and correlated with pre-FETO LiTR using linear regression analysis. For conservatively managed foetuses, only LiTR provided a significant prediction of postnatal survival. For foetuses undergoing FETO, LiTR and gestational age at delivery provided a significant independent prediction of postnatal survival. There was a significant inverse association between lung response and pre-FETO LiTR. In foetuses with CDH with/without FETO treatment, the LiTR is predictive of postnatal survival at discharge. In foetuses treated with FETO, LiTR is predictive of post-FETO lung response. aEuro cent Congenital diaphragmatic hernia is usually managed conservatively before surgery soon after delivery aEuro cent Fetoscopic endoluminal tracheal occlusion (FETO) has been introduced for severely affected foetuses aEuro cent In conservatively managed CDH, the liver-to-thoracic volume ratio (LiTR) predicted postnatal survival best. aEuro cent In severe CDH with prenatal FETO, LiTR also helped predict postnatal survival. aEuro cent LiTR should be integrated into the prenatal decision-making for foetuses with CDH

KW - Liver-to-thoracic volume ratio

KW - Diaphragmatic hernia

KW - Magnetic resonance imaging

KW - Tracheal occlusion

KW - Lung response

M3 - Article

VL - 23

SP - 1299

EP - 1305

JO - European Radiology

JF - European Radiology

SN - 0938-7994

IS - May

ER -

Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion.

Abstract

Keywords

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