Lumbar Puncture: Consensus Guidelines

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic workup of several neurological brain diseases. Reluctance to perform the procedure is among others due to a lack of standards and guidelines to minimize the risk of complications, such as post-LP headache or back pain. We provide a summary of consensus guidelines for the LP procedure to minimize the risk of complications.
Our consensus guidelines provide a step-by-step procedure description and address contraindications, as well as patient-related and procedure-related risk factors that can influence the development of post-LP complications. When an LP is performed correctly, the procedure is well tolerated and accepted with a low complication rate.
Original languageEnglish
Title of host publicationCerebrospinal Fluid Biomarkers
Subtitle of host publicationNeuromethods, vol. 168
Number of pages7
ISBN (Electronic)1940-6045
ISBN (Print)978-1-0716-1318-4
Publication statusPublished - 1 Jan 2021

Publication series

ISSN (Print)0893-2336
ISSN (Electronic)1940-6045


  • Lumbar puncture
  • cerebrospinal fluid
  • Evidence-based guidelines
  • Consensus guidelines
  • Headache
  • Post-LP complications
  • Back Pain


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