Lung cancer-fueled emergency myelopoiesis is characterized by an increase of S100A9+ and LCN2+ hematopoietic stem and progenitor cells

Evelyn Stephany Calderon Espinosa; Kirsten De Ridder; Mekhin Carpentier; Kim De Veirman; Daliya Kancheva; Isabelle Scheyltjens; Kiavash Movahedi; Kathleen Van den Eynde; Paul De Leyn; Lieven P Depypere; Sophie Hernot; Yanina Jansen; Cleo Goyvaerts

doi:10.64898/2026.02.24.707656

Lung cancer-fueled emergency myelopoiesis is characterized by an increase of S100A9+ and LCN2+ hematopoietic stem and progenitor cells

Evelyn Stephany Calderon Espinosa
, Kirsten De Ridder
, Mekhin Carpentier
, Kim De Veirman
, Daliya Kancheva
, Isabelle Scheyltjens
, Kiavash Movahedi
, Kathleen Van den Eynde
, Paul De Leyn
, Lieven P Depypere
, Sophie Hernot
, Yanina Jansen
, Cleo Goyvaerts

Research output: Contribution to journal › Article

Original language	English
Number of pages	40
Journal	bioRxiv
DOIs	https://doi.org/10.64898/2026.02.24.707656
Publication status	Published - 25 Feb 2026

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10.64898/2026.02.24.707656

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OZRIFTM9: Bone marrow niche – lung cancer crosstalk: gossip or fatal choice of words?
Goyvaerts, C. (Administrative Promotor) & Calderon Espinosa, E. S. (Mandate)
1/10/21 → 30/09/25
Project: Fundamental

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FWOAL1006: Creation of a 3D CRiMe scene to unravel Cytotoxicity Resistant Mechanisms in non-small cell lung cancer
Goyvaerts, C. (Administrative Promotor)
1/01/21 → 31/12/24
Project: Fundamental

Cite this

Calderon Espinosa, E. S., De Ridder, K., Carpentier, M., De Veirman, K., Kancheva, D., Scheyltjens, I., Movahedi, K., Van den Eynde, K., De Leyn, P., Depypere, L. P., Hernot, S., Jansen, Y., & Goyvaerts, C. (2026). Lung cancer-fueled emergency myelopoiesis is characterized by an increase of S100A9+ and LCN2+ hematopoietic stem and progenitor cells. bioRxiv. https://doi.org/10.64898/2026.02.24.707656

@article{2854d7b2a9da4b92aeadb63142f98dd4,

title = "Lung cancer-fueled emergency myelopoiesis is characterized by an increase of S100A9+ and LCN2+ hematopoietic stem and progenitor cells",

author = "\{Calderon Espinosa\}, \{Evelyn Stephany\} and \{De Ridder\}, Kirsten and Mekhin Carpentier and \{De Veirman\}, Kim and Daliya Kancheva and Isabelle Scheyltjens and Kiavash Movahedi and \{Van den Eynde\}, Kathleen and \{De Leyn\}, Paul and Depypere, \{Lieven P\} and Sophie Hernot and Yanina Jansen and Cleo Goyvaerts",

year = "2026",

month = feb,

day = "25",

doi = "10.64898/2026.02.24.707656",

language = "English",

journal = "bioRxiv",

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publisher = "Cold Spring Harbor Laboratory Press",

}

Calderon Espinosa, ES , De Ridder, K, Carpentier, M, De Veirman, K , Kancheva, D, Scheyltjens, I, Movahedi, K, Van den Eynde, K, De Leyn, P, Depypere, LP, Hernot, S, Jansen, Y & Goyvaerts, C 2026, 'Lung cancer-fueled emergency myelopoiesis is characterized by an increase of S100A9+ and LCN2+ hematopoietic stem and progenitor cells', bioRxiv. https://doi.org/10.64898/2026.02.24.707656

TY - JOUR

T1 - Lung cancer-fueled emergency myelopoiesis is characterized by an increase of S100A9+ and LCN2+ hematopoietic stem and progenitor cells

AU - Calderon Espinosa, Evelyn Stephany

AU - De Ridder, Kirsten

AU - Carpentier, Mekhin

AU - De Veirman, Kim

AU - Kancheva, Daliya

AU - Scheyltjens, Isabelle

AU - Movahedi, Kiavash

AU - Van den Eynde, Kathleen

AU - De Leyn, Paul

AU - Depypere, Lieven P

AU - Hernot, Sophie

AU - Jansen, Yanina

AU - Goyvaerts, Cleo

PY - 2026/2/25

Y1 - 2026/2/25

U2 - 10.64898/2026.02.24.707656

DO - 10.64898/2026.02.24.707656

M3 - Article

SN - 2692-8205

JO - bioRxiv

JF - bioRxiv

ER -

Lung cancer-fueled emergency myelopoiesis is characterized by an increase of S100A9+ and LCN2+ hematopoietic stem and progenitor cells

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Handle.net

Projects

OZRIFTM9: Bone marrow niche – lung cancer crosstalk: gossip or fatal choice of words?

FWOAL1006: Creation of a 3D CRiMe scene to unravel Cytotoxicity Resistant Mechanisms in non-small cell lung cancer

Cite this