Mass-manufacturable polymer microfluidic device for dual fiber optical trapping

Diane De Coster, Heidi Ottevaere, Michael Vervaeke, Jürgen Albert Van Erps, Manly Nestor Callewaert, Pieter Wuytens, Stephen H. Simpson, Simon Hanna, Wim De Malsche, Hugo Thienpont

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We present a microfluidic chip in Polymethyl methacrylate (PMMA) for optical trapping of particles in an 80 mu m wide microchannel using two counterpropagating single-mode beams. The trapping fibers are separated from the sample fluid by 70 mu m thick polymer walls. We calculate the optical forces that act on particles flowing in the microchannel using wave optics in combination with non-sequential ray-tracing and further mathematical processing. Our results are compared with a theoretical model and the Mie theory. We use a novel fabrication process that consists of a premilling step and ultraprecision diamond tooling for the manufacturing of the molds and double-sided hot embossing for replication, resulting in a robust microfluidic chip for optical trapping. In a proof-of-concept demonstration, we show the trapping capabilities of the hot embossed chip by trapping spherical beads with a diameter of 6 mu m, 8 mu m and 10 mu m and use the power spectrum analysis of the trapped particle displacements to characterize the trap strength. (c) 2015 Optical Society of America
Original languageEnglish
Pages (from-to)30991-31009
Number of pages19
JournalOpt. Express
Volume23
Issue number24
DOIs
Publication statusPublished - 30 Nov 2015

Keywords

  • Cell
  • Manipulation
  • System
  • Forces
  • Integration
  • Tweezers
  • Lasers
  • Beams

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