Maternal origin of extra haploid set of chromosomes in third trimester triploid fetuses

E Dietzsch; M Ramsay; A L Christianson; B D Henderson; T J de Ravel

doi:10.1002/ajmg.1320580412

Maternal origin of extra haploid set of chromosomes in third trimester triploid fetuses

E Dietzsch, M Ramsay, A L Christianson, B D Henderson, T J de Ravel

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Twenty-six highly polymorphic markers were used to determine the origin of the extra haploid chromosome set in 6 triploid fetuses of type II phenotype. All had reached the third trimester of pregnancy. The extra set was maternal in origin in all cases, supporting previous research indicating longer in utero survival of maternally-derived triploid fetuses. These findings provide evidence for an instance of genomic imprinting in humans.

Original language	English
Pages (from-to)	360-364
Number of pages	5
Journal	American Journal of Medical Genetics
Volume	58
Issue number	4
DOIs	https://doi.org/10.1002/ajmg.1320580412
Publication status	Published - 25 Sep 1995

Keywords

Adult
Chromosome Aberrations/embryology
Chromosome Disorders
Female
Fetal Growth Retardation/genetics
Genetic Markers
Genomic Imprinting
Gestational Age
Humans
Infant, Newborn
Male
Meiosis
Oogenesis
Polyploidy
Pregnancy

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10.1002/ajmg.1320580412

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title = "Maternal origin of extra haploid set of chromosomes in third trimester triploid fetuses",

abstract = "Twenty-six highly polymorphic markers were used to determine the origin of the extra haploid chromosome set in 6 triploid fetuses of type II phenotype. All had reached the third trimester of pregnancy. The extra set was maternal in origin in all cases, supporting previous research indicating longer in utero survival of maternally-derived triploid fetuses. These findings provide evidence for an instance of genomic imprinting in humans.",

keywords = "Adult, Chromosome Aberrations/embryology, Chromosome Disorders, Female, Fetal Growth Retardation/genetics, Genetic Markers, Genomic Imprinting, Gestational Age, Humans, Infant, Newborn, Male, Meiosis, Oogenesis, Polyploidy, Pregnancy",

author = "E Dietzsch and M Ramsay and Christianson, {A L} and Henderson, {B D} and {de Ravel}, {T J}",

year = "1995",

month = sep,

day = "25",

doi = "10.1002/ajmg.1320580412",

language = "English",

volume = "58",

pages = "360--364",

journal = "American Journal of Medical Genetics",

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TY - JOUR

T1 - Maternal origin of extra haploid set of chromosomes in third trimester triploid fetuses

AU - Dietzsch, E

AU - Ramsay, M

AU - Christianson, A L

AU - Henderson, B D

AU - de Ravel, T J

PY - 1995/9/25

Y1 - 1995/9/25

N2 - Twenty-six highly polymorphic markers were used to determine the origin of the extra haploid chromosome set in 6 triploid fetuses of type II phenotype. All had reached the third trimester of pregnancy. The extra set was maternal in origin in all cases, supporting previous research indicating longer in utero survival of maternally-derived triploid fetuses. These findings provide evidence for an instance of genomic imprinting in humans.

AB - Twenty-six highly polymorphic markers were used to determine the origin of the extra haploid chromosome set in 6 triploid fetuses of type II phenotype. All had reached the third trimester of pregnancy. The extra set was maternal in origin in all cases, supporting previous research indicating longer in utero survival of maternally-derived triploid fetuses. These findings provide evidence for an instance of genomic imprinting in humans.

KW - Adult

KW - Chromosome Aberrations/embryology

KW - Chromosome Disorders

KW - Female

KW - Fetal Growth Retardation/genetics

KW - Genetic Markers

KW - Genomic Imprinting

KW - Gestational Age

KW - Humans

KW - Infant, Newborn

KW - Male

KW - Meiosis

KW - Oogenesis

KW - Polyploidy

KW - Pregnancy

U2 - 10.1002/ajmg.1320580412

DO - 10.1002/ajmg.1320580412

M3 - Article

C2 - 8533847

VL - 58

SP - 360

EP - 364

JO - American Journal of Medical Genetics

JF - American Journal of Medical Genetics

SN - 0148-7299

IS - 4

ER -

Maternal origin of extra haploid set of chromosomes in third trimester triploid fetuses

Abstract

Keywords

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