Measurement of Interstitial Space Dispersion in Packed Bed Columns: Comparison of Superficially Porous and Fully Porous Particles

The difference in packing quality of superficially porous and fully porous columns has been measured using the total pore blocking technique. This technique physically eliminates all mass transfer band broadening contributions, and hence provides the purest possible measure of the packing quality of a column. The measurements confirm earlier assertions made in the literature about the generally better packing quality of superficially porous columns over fully porous particle based columns.