Myelofibrosis patients in Belgium: disease characteristics.

Timothy Devos; P. Zachee; D. Bron; L. Noens; Jan Van Droogenbroeck; P. Mineur; Yves Beguin; Zwi Berneman; Fs Benghiat; A. Kentos; C. Chatelain; H. Demuynck; J. Lemmens; Kg Eygen; Koen Theunissen; Fabienne Trullemans; P. Pierre; W. Pluymers; Laurent Knoops

Myelofibrosis patients in Belgium: disease characteristics.

Timothy Devos, P. Zachee, D. Bron, L. Noens, Jan Van Droogenbroeck, P. Mineur, Yves Beguin, Zwi Berneman, Fs Benghiat, A. Kentos, C. Chatelain, H. Demuynck, J. Lemmens, Kg Eygen, Koen Theunissen, Fabienne Trullemans, P. Pierre, W. Pluymers, Laurent Knoops

Hematology

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according to pre-defined disease parameters (diagnosis, risk categories, hemoglobin 50.000/µl and 201 (80%) had platelet count >100.000/µl. Of 250 patients, 85 (34%) had a myeloblast count >1%. Six (2%) patients had undergone a splenectomy. Thirteen (5* 2%) patients had undergone radiotherapy for splenomegaly. Conclusions: The results of this survey provide insight into the characteristics of the Belgian myelofibrosis population. They also suggest that a large proportion of these patients could stand to benefit from the therapies currently under development.

Original language	English
Pages (from-to)	105-111
Journal	Acta Clin Belg
Volume	70
Issue number	2
Early online date	6 Nov 2014
Publication status	Published - Apr 2015

Keywords

Myelofibrosis

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Devos, Timothy ; Zachee, P. ; Bron, D. ; Noens, L. ; Van Droogenbroeck, Jan ; Mineur, P. ; Beguin, Yves ; Berneman, Zwi ; Benghiat, Fs ; Kentos, A. ; Chatelain, C. ; Demuynck, H. ; Lemmens, J. ; Eygen, Kg ; Theunissen, Koen ; Trullemans, Fabienne ; Pierre, P. ; Pluymers, W. ; Knoops, Laurent. / Myelofibrosis patients in Belgium: disease characteristics. In: Acta Clin Belg. 2015 ; Vol. 70, No. 2. pp. 105-111.

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title = "Myelofibrosis patients in Belgium: disease characteristics.",

abstract = "Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according to pre-defined disease parameters (diagnosis, risk categories, hemoglobin 50.000/µl and 201 (80%) had platelet count >100.000/µl. Of 250 patients, 85 (34%) had a myeloblast count >1%. Six (2%) patients had undergone a splenectomy. Thirteen (5* 2%) patients had undergone radiotherapy for splenomegaly. Conclusions: The results of this survey provide insight into the characteristics of the Belgian myelofibrosis population. They also suggest that a large proportion of these patients could stand to benefit from the therapies currently under development.",

keywords = "Myelofibrosis",

author = "Timothy Devos and P. Zachee and D. Bron and L. Noens and {Van Droogenbroeck}, Jan and P. Mineur and Yves Beguin and Zwi Berneman and Fs Benghiat and A. Kentos and C. Chatelain and H. Demuynck and J. Lemmens and Kg Eygen and Koen Theunissen and Fabienne Trullemans and P. Pierre and W. Pluymers and Laurent Knoops",

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Myelofibrosis patients in Belgium: disease characteristics. / Devos, Timothy; Zachee, P.; Bron, D.; Noens, L.; Van Droogenbroeck, Jan; Mineur, P.; Beguin, Yves; Berneman, Zwi; Benghiat, Fs; Kentos, A.; Chatelain, C.; Demuynck, H.; Lemmens, J.; Eygen, Kg; Theunissen, Koen; Trullemans, Fabienne; Pierre, P.; Pluymers, W.; Knoops, Laurent.

In: Acta Clin Belg, Vol. 70, No. 2, 04.2015, p. 105-111.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Myelofibrosis patients in Belgium: disease characteristics.

AU - Devos, Timothy

AU - Zachee, P.

AU - Bron, D.

AU - Noens, L.

AU - Van Droogenbroeck, Jan

AU - Mineur, P.

AU - Beguin, Yves

AU - Berneman, Zwi

AU - Benghiat, Fs

AU - Kentos, A.

AU - Chatelain, C.

AU - Demuynck, H.

AU - Lemmens, J.

AU - Eygen, Kg

AU - Theunissen, Koen

AU - Trullemans, Fabienne

AU - Pierre, P.

AU - Pluymers, W.

AU - Knoops, Laurent

PY - 2015/4

Y1 - 2015/4

N2 - Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according to pre-defined disease parameters (diagnosis, risk categories, hemoglobin 50.000/µl and 201 (80%) had platelet count >100.000/µl. Of 250 patients, 85 (34%) had a myeloblast count >1%. Six (2%) patients had undergone a splenectomy. Thirteen (5* 2%) patients had undergone radiotherapy for splenomegaly. Conclusions: The results of this survey provide insight into the characteristics of the Belgian myelofibrosis population. They also suggest that a large proportion of these patients could stand to benefit from the therapies currently under development.

AB - Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according to pre-defined disease parameters (diagnosis, risk categories, hemoglobin 50.000/µl and 201 (80%) had platelet count >100.000/µl. Of 250 patients, 85 (34%) had a myeloblast count >1%. Six (2%) patients had undergone a splenectomy. Thirteen (5* 2%) patients had undergone radiotherapy for splenomegaly. Conclusions: The results of this survey provide insight into the characteristics of the Belgian myelofibrosis population. They also suggest that a large proportion of these patients could stand to benefit from the therapies currently under development.

KW - Myelofibrosis

M3 - Article

VL - 70

SP - 105

EP - 111

JO - Acta Clinica Belgica

JF - Acta Clinica Belgica

SN - 1784-3286

IS - 2

ER -

Myelofibrosis patients in Belgium: disease characteristics.

Abstract

Keywords

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