Numerical Simulations of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): Effect of Inertial Impaction

Mohammad Rahimi-Gorji, Charlotte Debbaut, Ghader Ghorbaniasl, Wouter Willaert, Wim Ceelen

Research output: Chapter in Book/Report/Conference proceedingConference paper

Abstract

Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is a novel method to treat peritoneal metastases by intraperitoneal nebulization of chemotherapy. Homogeneous distribution of the resulting aerosol is hampered by inertial impaction of aerosol droplets, and by gravitational acceleration. Here, we used computational fluid dynamics (CFD) to simulate the effect of inertial impaction on spatial aerosol distribution during PIPAC.
Original languageEnglish
Title of host publicationOncoDot. 3 symposium 2021
Subtitle of host publicationCancer Research Institute Ghent (CRIG)
Place of PublicationVirtual Meeting
Number of pages1
Publication statusPublished - 2021

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