Opioid receptor binding agents and uses thereof

Jan Steyaert; Toon Laeremans; Els Pardon; Brian K Kobilka; Aashish Manglik

Opioid receptor binding agents and uses thereof

Jan Steyaert (Inventor), Toon Laeremans (Inventor), Els Pardon (Inventor), Brian K Kobilka (Inventor), Aashish Manglik (Inventor)

Research output: Patent

Abstract

Agents that specifically bind to an opioid receptor in a conformationally specific way can be used to induce a conformational change in the receptor. Such agents have therapeutic applications and can be used in X-ray crystallography studies of the receptor. Such agents can also be used to improve drug discovery via compound screening and/or structure-based drug design.

Original language	English
Patent number	US11352422
Publication status	Published - 2022

Cite this

@misc{a6b1c469da8b4a168f0263c4beb37d7e,

title = "Opioid receptor binding agents and uses thereof",

abstract = "Agents that specifically bind to an opioid receptor in a conformationally specific way can be used to induce a conformational change in the receptor. Such agents have therapeutic applications and can be used in X-ray crystallography studies of the receptor. Such agents can also be used to improve drug discovery via compound screening and/or structure-based drug design.",

author = "Jan Steyaert and Toon Laeremans and Els Pardon and Kobilka, {Brian K} and Aashish Manglik",

year = "2022",

language = "English",

type = "Patent",

note = "US11352422",

}

TY - PAT

T1 - Opioid receptor binding agents and uses thereof

AU - Steyaert, Jan

AU - Laeremans, Toon

AU - Pardon, Els

AU - Kobilka, Brian K

AU - Manglik, Aashish

PY - 2022

Y1 - 2022

N2 - Agents that specifically bind to an opioid receptor in a conformationally specific way can be used to induce a conformational change in the receptor. Such agents have therapeutic applications and can be used in X-ray crystallography studies of the receptor. Such agents can also be used to improve drug discovery via compound screening and/or structure-based drug design.

AB - Agents that specifically bind to an opioid receptor in a conformationally specific way can be used to induce a conformational change in the receptor. Such agents have therapeutic applications and can be used in X-ray crystallography studies of the receptor. Such agents can also be used to improve drug discovery via compound screening and/or structure-based drug design.

UR - http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=US11352422&F=0

M3 - Patent

M1 - US11352422

ER -

Opioid receptor binding agents and uses thereof

Abstract

Other files and links

Fingerprint

IOF3011: GEAR: Nanobodies for Biotechnology and Health

Cite this

Opioid receptor binding agents and uses thereof

Abstract

Other files and links

Fingerprint

Projects

IOF3011: GEAR: Nanobodies for Biotechnology and Health

Cite this