Optic Nerve Biopsies in Unexplained Progressive Optic Neuropathy in Two Adults Reveal Optic Nerve Gliomas

Michel van Lint; Dave Kloeck; Rob J W de Keizer

doi:10.1097/WNO.0000000000001529

Optic Nerve Biopsies in Unexplained Progressive Optic Neuropathy in Two Adults Reveal Optic Nerve Gliomas

Michel van Lint, Dave Kloeck, Rob J W de Keizer

Ophthalmology - Eye surgery

Research output: Contribution to journal › Article › peer-review

Abstract

Two patients with an optic nerve glioma are discussed. The first patient presents with a chronic optic disc edema. Biopsy reveals a pilocytic astrocytoma of the optic nerve as part of a multicentric glioma. Biopsy of a temporal lobe nodule demonstrates a glioblastoma. The second patient is treated for glaucoma, but continues to develop progressive visual loss. Optic nerve biopsy shows a pilocytic astrocytoma, but it has reached the optic chiasm rendering both eyes blind.

Original language	English
Pages (from-to)	e224-e226
Number of pages	3
Journal	Journal of Neuro-Ophthalmology
Volume	43
Issue number	4
DOIs	https://doi.org/10.1097/WNO.0000000000001529
Publication status	Published - 1 Dec 2023

Keywords

Adult
Humans
Optic Nerve Glioma/complications
Optic Nerve/diagnostic imaging
Optic Nerve Diseases/diagnosis
Biopsy

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10.1097/WNO.0000000000001529

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title = "Optic Nerve Biopsies in Unexplained Progressive Optic Neuropathy in Two Adults Reveal Optic Nerve Gliomas",

abstract = "Two patients with an optic nerve glioma are discussed. The first patient presents with a chronic optic disc edema. Biopsy reveals a pilocytic astrocytoma of the optic nerve as part of a multicentric glioma. Biopsy of a temporal lobe nodule demonstrates a glioblastoma. The second patient is treated for glaucoma, but continues to develop progressive visual loss. Optic nerve biopsy shows a pilocytic astrocytoma, but it has reached the optic chiasm rendering both eyes blind.",

keywords = "Adult, Humans, Optic Nerve Glioma/complications, Optic Nerve/diagnostic imaging, Optic Nerve Diseases/diagnosis, Biopsy",

author = "{van Lint}, Michel and Dave Kloeck and {de Keizer}, {Rob J W}",

year = "2023",

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doi = "10.1097/WNO.0000000000001529",

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AU - van Lint, Michel

AU - Kloeck, Dave

AU - de Keizer, Rob J W

PY - 2023/12/1

Y1 - 2023/12/1

N2 - Two patients with an optic nerve glioma are discussed. The first patient presents with a chronic optic disc edema. Biopsy reveals a pilocytic astrocytoma of the optic nerve as part of a multicentric glioma. Biopsy of a temporal lobe nodule demonstrates a glioblastoma. The second patient is treated for glaucoma, but continues to develop progressive visual loss. Optic nerve biopsy shows a pilocytic astrocytoma, but it has reached the optic chiasm rendering both eyes blind.

AB - Two patients with an optic nerve glioma are discussed. The first patient presents with a chronic optic disc edema. Biopsy reveals a pilocytic astrocytoma of the optic nerve as part of a multicentric glioma. Biopsy of a temporal lobe nodule demonstrates a glioblastoma. The second patient is treated for glaucoma, but continues to develop progressive visual loss. Optic nerve biopsy shows a pilocytic astrocytoma, but it has reached the optic chiasm rendering both eyes blind.

KW - Adult

KW - Humans

KW - Optic Nerve Glioma/complications

KW - Optic Nerve/diagnostic imaging

KW - Optic Nerve Diseases/diagnosis

KW - Biopsy

U2 - 10.1097/WNO.0000000000001529

DO - 10.1097/WNO.0000000000001529

M3 - Article

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SN - 1070-8022

VL - 43

SP - e224-e226

JO - Journal of Neuro-Ophthalmology

JF - Journal of Neuro-Ophthalmology

IS - 4

ER -

Optic Nerve Biopsies in Unexplained Progressive Optic Neuropathy in Two Adults Reveal Optic Nerve Gliomas

Abstract

Keywords

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