Overuse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice

Didier Cataldo, Eric Derom, Giuseppe Liistro, Eric Marchand, Vincent Ninane, Rudi Peché, Hans Slabbynck, Walter Vincken, Wim Janssens

Research output: Contribution to journalScientific reviewpeer-review

30 Citations (Scopus)


Evidence and guidelines are becoming increasingly clear about imbalance between the risks and benefits of inhaled corticosteroids (ICSs) in patients with COPD. While selected patients may benefit from ICS-containing regimens, ICSs are often inappropriately prescribed with - according to Belgian market research data - up to 70% of patients in current practice receiving ICSs, usually as a fixed combination with a long-acting β2-adrenoreceptor agonist. Studies and recommendations support withdrawal of ICSs in a large group of patients with COPD. However, historical habits appear difficult to change even in the light of recent scientific evidence. We have built a collaborative educational platform with chest physicians and primary care physicians to increase awareness and provide guidance and support in this matter.

Original languageEnglish
Pages (from-to)2089-2099
Number of pages11
JournalInternational Journal of Chronic Obstructive Pulmonary Disease
Publication statusPublished - 2018


  • COPD
  • Education
  • Exacerbation
  • Inhaled steroids
  • Systematic review
  • Withdrawal


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