P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size.

G. Mugnai, Jean-Baptiste Chierchia, Carlo De Asmundis, J. Julia, G. Conte, Juan Antonio Sieira Rodriguez-Moret, Lucio Capulzini Cremonini, Kristel Wauters, M. Rodriguez-Mañero, Giuseppe Ciconte, G. Baltogiannis, G. Di Giovanni, Y. Saitoh, Pedro Brugada

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

AIMS:

Prolonged P-wave duration and dispersion are universally accepted noninvasive markers for atrial electrical remodeling. Our aim was to analyze P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in patients with normal left atrial size.

METHODS:

From January 2008 to December 2011, 426 patients with drug-resistant symptomatic paroxysmal atrial fibrillation underwent pulmonary vein isolation as an index procedure by conventional radiofrequency or cryoballoon ablation in our center. Patients with left atrial dilatation, poor-quality electrocardiograms, atrial pacemaker stimulation, and those undergoing repeat procedures were excluded. A total of 201 patients were analyzed during a mean follow-up of 22?±?16 months.

RESULTS:

Patients with prolonged P-wave duration had higher rates of atrial fibrillation recurrences compared with those without prolonged P-wave duration (49 vs. 14%; P?
CONCLUSION:

Prolonged P-wave duration and dispersion were found to be independently associated with higher recurrence rates of atrial fibrillation after pulmonary vein isolation in patients with normal left atrial dimension. Therefore, a prolongation of P-wave indices may help to identify those patients in whom electrical remodeling has already occurred and a more extensive ablation may be indicated.
Original languageEnglish
Pages (from-to)194-200
Number of pages7
JournalJ. Cardiovasc. Med.
Volume17
Issue number3
DOIs
Publication statusPublished - Mar 2016

Keywords

  • P-wave
  • atrial fibrillation
  • pulmonary vein isolation

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