P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size.

G. Mugnai; Jean-Baptiste Chierchia; Carlo De Asmundis; J. Julia; G. Conte; Juan Antonio Sieira Rodriguez-Moret; Lucio Capulzini Cremonini; Kristel Wauters; M. Rodriguez-Mañero; Giuseppe Ciconte; G. Baltogiannis; G. Di Giovanni; Y. Saitoh; Pedro Brugada

doi:10.2459/JCM.0000000000000220

P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size.

G. Mugnai, Jean-Baptiste Chierchia, Carlo De Asmundis, J. Julia, G. Conte, Juan Antonio Sieira Rodriguez-Moret, Lucio Capulzini Cremonini, Kristel Wauters, M. Rodriguez-Mañero, Giuseppe Ciconte, G. Baltogiannis, G. Di Giovanni, Y. Saitoh, Pedro Brugada

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27 Citations (Scopus)

Abstract

AIMS:

Prolonged P-wave duration and dispersion are universally accepted noninvasive markers for atrial electrical remodeling. Our aim was to analyze P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in patients with normal left atrial size.

METHODS:

From January 2008 to December 2011, 426 patients with drug-resistant symptomatic paroxysmal atrial fibrillation underwent pulmonary vein isolation as an index procedure by conventional radiofrequency or cryoballoon ablation in our center. Patients with left atrial dilatation, poor-quality electrocardiograms, atrial pacemaker stimulation, and those undergoing repeat procedures were excluded. A total of 201 patients were analyzed during a mean follow-up of 22?±?16 months.

RESULTS:

Patients with prolonged P-wave duration had higher rates of atrial fibrillation recurrences compared with those without prolonged P-wave duration (49 vs. 14%; P?
CONCLUSION:

Prolonged P-wave duration and dispersion were found to be independently associated with higher recurrence rates of atrial fibrillation after pulmonary vein isolation in patients with normal left atrial dimension. Therefore, a prolongation of P-wave indices may help to identify those patients in whom electrical remodeling has already occurred and a more extensive ablation may be indicated.

Original language	English
Pages (from-to)	194-200
Number of pages	7
Journal	J. Cardiovasc. Med.
Volume	17
Issue number	3
DOIs	https://doi.org/10.2459/JCM.0000000000000220
Publication status	Published - Mar 2016

Keywords

P-wave
atrial fibrillation
pulmonary vein isolation

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10.2459/JCM.0000000000000220

http://journals.lww.com/jcardiovascularmedicine/pages/articleviewer.aspx?year=2016&issue=03000&article=00005&type=abstract

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Mugnai, G., Chierchia, J.-B., De Asmundis, C., Julia, J., Conte, G., Sieira Rodriguez-Moret, J. A., Capulzini Cremonini, L., Wauters, K., Rodriguez-Mañero, M., Ciconte, G., Baltogiannis, G., Di Giovanni, G., Saitoh, Y., & Brugada, P. (2016). P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size. J. Cardiovasc. Med., 17(3), 194-200. https://doi.org/10.2459/JCM.0000000000000220

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title = "P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size.",

abstract = "AIMS: Prolonged P-wave duration and dispersion are universally accepted noninvasive markers for atrial electrical remodeling. Our aim was to analyze P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in patients with normal left atrial size. METHODS: From January 2008 to December 2011, 426 patients with drug-resistant symptomatic paroxysmal atrial fibrillation underwent pulmonary vein isolation as an index procedure by conventional radiofrequency or cryoballoon ablation in our center. Patients with left atrial dilatation, poor-quality electrocardiograms, atrial pacemaker stimulation, and those undergoing repeat procedures were excluded. A total of 201 patients were analyzed during a mean follow-up of 22?±?16 months. RESULTS: Patients with prolonged P-wave duration had higher rates of atrial fibrillation recurrences compared with those without prolonged P-wave duration (49 vs. 14%; P? CONCLUSION: Prolonged P-wave duration and dispersion were found to be independently associated with higher recurrence rates of atrial fibrillation after pulmonary vein isolation in patients with normal left atrial dimension. Therefore, a prolongation of P-wave indices may help to identify those patients in whom electrical remodeling has already occurred and a more extensive ablation may be indicated.",

keywords = "P-wave, atrial fibrillation, pulmonary vein isolation",

author = "G. Mugnai and Jean-Baptiste Chierchia and {De Asmundis}, Carlo and J. Julia and G. Conte and {Sieira Rodriguez-Moret}, {Juan Antonio} and {Capulzini Cremonini}, Lucio and Kristel Wauters and M. Rodriguez-Ma{\~n}ero and Giuseppe Ciconte and G. Baltogiannis and {Di Giovanni}, G. and Y. Saitoh and Pedro Brugada",

year = "2016",

month = mar,

doi = "10.2459/JCM.0000000000000220",

language = "English",

volume = "17",

pages = "194--200",

journal = "J. Cardiovasc. Med.",

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Mugnai, G, Chierchia, J-B , De Asmundis, C, Julia, J, Conte, G, Sieira Rodriguez-Moret, JA, Capulzini Cremonini, L, Wauters, K, Rodriguez-Mañero, M, Ciconte, G, Baltogiannis, G, Di Giovanni, G, Saitoh, Y & Brugada, P 2016, 'P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size.', J. Cardiovasc. Med., vol. 17, no. 3, pp. 194-200. https://doi.org/10.2459/JCM.0000000000000220

TY - JOUR

T1 - P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size.

AU - Mugnai, G.

AU - Chierchia, Jean-Baptiste

AU - De Asmundis, Carlo

AU - Julia, J.

AU - Conte, G.

AU - Sieira Rodriguez-Moret, Juan Antonio

AU - Capulzini Cremonini, Lucio

AU - Wauters, Kristel

AU - Rodriguez-Mañero, M.

AU - Ciconte, Giuseppe

AU - Baltogiannis, G.

AU - Di Giovanni, G.

AU - Saitoh, Y.

AU - Brugada, Pedro

PY - 2016/3

Y1 - 2016/3

N2 - AIMS: Prolonged P-wave duration and dispersion are universally accepted noninvasive markers for atrial electrical remodeling. Our aim was to analyze P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in patients with normal left atrial size. METHODS: From January 2008 to December 2011, 426 patients with drug-resistant symptomatic paroxysmal atrial fibrillation underwent pulmonary vein isolation as an index procedure by conventional radiofrequency or cryoballoon ablation in our center. Patients with left atrial dilatation, poor-quality electrocardiograms, atrial pacemaker stimulation, and those undergoing repeat procedures were excluded. A total of 201 patients were analyzed during a mean follow-up of 22?±?16 months. RESULTS: Patients with prolonged P-wave duration had higher rates of atrial fibrillation recurrences compared with those without prolonged P-wave duration (49 vs. 14%; P? CONCLUSION: Prolonged P-wave duration and dispersion were found to be independently associated with higher recurrence rates of atrial fibrillation after pulmonary vein isolation in patients with normal left atrial dimension. Therefore, a prolongation of P-wave indices may help to identify those patients in whom electrical remodeling has already occurred and a more extensive ablation may be indicated.

AB - AIMS: Prolonged P-wave duration and dispersion are universally accepted noninvasive markers for atrial electrical remodeling. Our aim was to analyze P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in patients with normal left atrial size. METHODS: From January 2008 to December 2011, 426 patients with drug-resistant symptomatic paroxysmal atrial fibrillation underwent pulmonary vein isolation as an index procedure by conventional radiofrequency or cryoballoon ablation in our center. Patients with left atrial dilatation, poor-quality electrocardiograms, atrial pacemaker stimulation, and those undergoing repeat procedures were excluded. A total of 201 patients were analyzed during a mean follow-up of 22?±?16 months. RESULTS: Patients with prolonged P-wave duration had higher rates of atrial fibrillation recurrences compared with those without prolonged P-wave duration (49 vs. 14%; P? CONCLUSION: Prolonged P-wave duration and dispersion were found to be independently associated with higher recurrence rates of atrial fibrillation after pulmonary vein isolation in patients with normal left atrial dimension. Therefore, a prolongation of P-wave indices may help to identify those patients in whom electrical remodeling has already occurred and a more extensive ablation may be indicated.

KW - P-wave

KW - atrial fibrillation

KW - pulmonary vein isolation

U2 - 10.2459/JCM.0000000000000220

DO - 10.2459/JCM.0000000000000220

M3 - Article

SN - 1558-2027

VL - 17

SP - 194

EP - 200

JO - J. Cardiovasc. Med.

JF - J. Cardiovasc. Med.

IS - 3

ER -

P-wave indices as predictors of atrial fibrillation recurrence after pulmonary vein isolation in normal left atrial size.

Abstract

Keywords

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