Prophylactic use of probiotics for gastrointestinal disorders in children

Celine Perceval, Hania Szajewska, Flavia Indrio, Zvi Weizman, Yvan Vandenplas

Research output: Contribution to journalScientific reviewpeer-review

27 Citations (Scopus)


The gastrointestinal microbiome is a hot topic in clinical research. Beneficial effects of selected probiotics in the prevention of gastrointestinal disorders are mainly restricted to acute gastroenteritis, antibiotic-associated diarrhoea, infantile colic, and necrotising enterocolitis. However, no broad consensus exists to recommend the use of probiotics in the prevention of these conditions, mainly because of the different design of the studies done so far, resulting in little evidence for specific strains, dosages, and indications. More well designed studies are needed before recommendations can be proposed. At this stage, the evidence is insufficient to recommend the routine use of probiotics in infants and children for the prevention of gastrointestinal disorders.

Original languageEnglish
Pages (from-to)655-662
Number of pages8
JournalThe Lancet. Child & adolescent health
Issue number9
Publication statusPublished - Sep 2019

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