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Abstract
Layer-by-Layer coating technology is of great importance for many applications of microparticles whereby exposure of the particles to various reagents is needed. Mutual contamination of the reagents during this process is a key challenge, and this undesired effect should be avoided. Here we introduce a device that provides subsequent exposure of particles to various liquids and minimizes mixing of the liquids at the same time. The key element of the device is a rail (groove) at the bottom of a microfluidic channel. The rail forms an angle (between 0 and 90 degrees) and thus enables passive transport of particles through the intact co-flows of the different fluids. To avoid the undesirable effect of reagent stream mixing, internal walls are introduced to separate the different flows. Various designs of the proposed device are considered, and their performance is experimentally analyzed.
Original language | English |
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Pages (from-to) | 1231-1240 |
Number of pages | 10 |
Journal | Soft Matter |
Volume | 19 |
Issue number | 6 |
Early online date | 16 Jan 2023 |
DOIs | |
Publication status | Published - 8 Feb 2023 |
Bibliographical note
Funding Information:We thank Prof. Ruslan Efremov for giving access to his profilometer instrument. This work was partially supported by Research Foundation-Flanders (FWO-Vl), Grant no. G029322N, Grant no. 1512018N, and by Innoviris (‘Colores’ Bridge type project).
Publisher Copyright:
© 2023 The Royal Society of Chemistry.
Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.
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- 1 Finished
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SRP51: SRP-Onderzoekszwaartepunt: Optical and microfluidic tools to unravel the dynamics of bio-condensates
De Malsche, W., Ottevaere, H., Maes, D. & Tompa, P.
1/03/19 → 29/02/24
Project: Fundamental