Response of the oxygen uptake efficiency slope to exercise training in patients with chronic heart failure

Christophe Van Laethem, Nico Van De Veire, G. De Backer, Salhi Bihija, Tony Seghers, Dirk Cambier, M. Vanderheyden, Johan De Sutter

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)

Abstract

Background: The oxygen uptake efficiency slope (DUES) is a new exercise parameter that provides prognostic power in patients with CHF. Little is known about the effects of exercise training (ET) on OUES.
Aim: To describe the response of OUES to 6 months of ET in CHF patients and compare its evolution to that of other exercise variables.

Methods: 35 patients with CHF (NYHA II-III, age 54 +/- 9y, LVEF 31 +/- 10%) performed 3 maximal exercise tests, i.e. at the start, middle and end of a 6 month ET program. OUES, PeakVO(2), ventilatory anaerobic threshold (VAT) and slope VENCO2 were determined.

Results: DUES, peakVO(2), VAT, slope VENCO2, peak Watt, 6MWT and NYHA-class improved during the first part of the ET period (p
Discussion: OUES improves significantly after 6 months of ET. Changes in peakVO(2) correlate best with changes in OUES. OUES is sensitive to ET and can be used to evaluate the progression of exercise capacity in CHF patients. (C) 2007 European Society of Cardiology. Published by Elsevier B.V All rights reserved.
Original languageEnglish
Pages (from-to)625-629
Number of pages5
JournalEuropean Journal of Heart Failure
Volume9
Issue number6-7
Publication statusPublished - Jul 2007

Keywords

  • exercise training
  • heart failure
  • ventilation

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