Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri

Michal Respondek; Lieven Buts; Natalie De Jonge; Sarah Haesaerts; Remy Loris; Laurence Van Melderen; Lode Wyns; Klaus Zangger

Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri

Michal Respondek, Lieven Buts, Natalie De Jonge, Sarah Haesaerts, Remy Loris, Laurence Van Melderen, Lode Wyns, Klaus Zangger

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

CcdB is the toxic component of a bacterial toxin-antitoxin system. It inhibits DNA gyrase (a type II
topoisomerase), and its toxicity can be neutralized by binding of its antitoxin CcdA. Here we report the sequential backbone and sidechain 1H, 15N and 13C resonance assignments of CcdBVfi from the marine bacterium Vibrio fischeri. The BMRB accession number is 16135.

Original language	English
Pages (from-to)	145-147
Number of pages	3
Journal	Biomol. NMR Assign.
Volume	3
Publication status	Published - 2009

Keywords

toxin-antitoxin
NMR

OZR1823: Structural basis of plasmid addiction and programmed cell death in bacteria
Loris, R.
1/10/08 → 30/09/09
Project: Fundamental
FWOAL381: Structural basis of plasmide addiction and programed cell death in bacteria
Haesaerts, S., De Greve, H. & Loris, R.
1/01/06 → 31/12/09
Project: Fundamental
OZR448: Structural biology of a plasmid addiction system.
Loris, R.
1/01/00 → 31/12/01
Project: Fundamental

2 Talk or presentation at a workshop/seminar
1 Membership of external research organisation
1 Talk or presentation at a conference

International Union of Crystallography (IUCr) Congress and general Assembly 2011
Remy Loris (Keynote speaker)
22 Aug 2011 → 30 Aug 2011
Activity: Talk or presentation › Talk or presentation at a conference
Workshop around the properties of Naturally Unstructured Proteins
Remy Loris (Keynote speaker)
9 Jan 2009
Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Universtité de Liège seminar series
Remy Loris (Keynote speaker)
25 Mar 2009
Activity: Talk or presentation › Talk or presentation at a workshop/seminar

Cite this

@article{1ecf5be4e7a3418ba98c2afd8854cc24,

title = "Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri",

abstract = "CcdB is the toxic component of a bacterial toxin-antitoxin system. It inhibits DNA gyrase (a type II topoisomerase), and its toxicity can be neutralized by binding of its antitoxin CcdA. Here we report the sequential backbone and sidechain 1H, 15N and 13C resonance assignments of CcdBVfi from the marine bacterium Vibrio fischeri. The BMRB accession number is 16135.",

keywords = "toxin-antitoxin, NMR",

author = "Michal Respondek and Lieven Buts and {De Jonge}, Natalie and Sarah Haesaerts and Remy Loris and {Van Melderen}, Laurence and Lode Wyns and Klaus Zangger",

year = "2009",

language = "English",

volume = "3",

pages = "145--147",

journal = "Biomolecular NMR Assignments",

issn = "1874-2718",

publisher = "Springer Netherlands",

}

Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri. / Respondek, Michal; Buts, Lieven; De Jonge, Natalie; Haesaerts, Sarah ; Loris, Remy; Van Melderen, Laurence; Wyns, Lode; Zangger, Klaus.

In: Biomol. NMR Assign., Vol. 3, 2009, p. 145-147.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri

AU - Respondek, Michal

AU - Buts, Lieven

AU - De Jonge, Natalie

AU - Haesaerts, Sarah

AU - Loris, Remy

AU - Van Melderen, Laurence

AU - Wyns, Lode

AU - Zangger, Klaus

PY - 2009

Y1 - 2009

N2 - CcdB is the toxic component of a bacterial toxin-antitoxin system. It inhibits DNA gyrase (a type II topoisomerase), and its toxicity can be neutralized by binding of its antitoxin CcdA. Here we report the sequential backbone and sidechain 1H, 15N and 13C resonance assignments of CcdBVfi from the marine bacterium Vibrio fischeri. The BMRB accession number is 16135.

AB - CcdB is the toxic component of a bacterial toxin-antitoxin system. It inhibits DNA gyrase (a type II topoisomerase), and its toxicity can be neutralized by binding of its antitoxin CcdA. Here we report the sequential backbone and sidechain 1H, 15N and 13C resonance assignments of CcdBVfi from the marine bacterium Vibrio fischeri. The BMRB accession number is 16135.

KW - toxin-antitoxin

KW - NMR

M3 - Article

VL - 3

SP - 145

EP - 147

JO - Biomolecular NMR Assignments

JF - Biomolecular NMR Assignments

SN - 1874-2718

ER -

Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri

Abstract

Keywords

Fingerprint

Projects

OZR1823: Structural basis of plasmid addiction and programmed cell death in bacteria

FWOAL381: Structural basis of plasmide addiction and programed cell death in bacteria

OZR448: Structural biology of a plasmid addiction system.

Activities

International Union of Crystallography (IUCr) Congress and general Assembly 2011

Workshop around the properties of Naturally Unstructured Proteins

Universtité de Liège seminar series

Cite this