Setting up a  PDXO platform of pancreatic cancer with spatial-omics characterization

Ellis Michiels; Ilse Rooman; Yves Heremans

Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

Ellis Michiels, Ilse Rooman, Yves Heremans

Research output: Unpublished contribution to conference › Poster

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC.

Original language	English
Publication status	Published - 10 Jun 2021
Event	European Pancreatic Club - Verona - online event Duration: 9 Jun 2021 → 11 Jun 2021

Conference

Conference	European Pancreatic Club
Period	9/06/21 → 11/06/21

1 Finished
1 Active

SRP65: SRP-Groeifinanciering: Molecular Portrait of Pancreatic Tumours: Veni, vidi, vici
Rooman, I. & De Grève, J.
1/03/19 → 31/12/26
Project: Fundamental
FWOODYS12: De-convolution of tumour biology in the post-genomic era: focus on pancreatic cancer
Rooman, I.
1/10/16 → 1/10/21
Project: Fundamental

Cite this

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title = "Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization",

abstract = "Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC. ",

author = "Ellis Michiels and Ilse Rooman and Yves Heremans",

year = "2021",

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note = "European Pancreatic Club ; Conference date: 09-06-2021 Through 11-06-2021",

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TY - CONF

T1 - Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

AU - Michiels, Ellis

AU - Rooman, Ilse

AU - Heremans, Yves

PY - 2021/6/10

Y1 - 2021/6/10

N2 - Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC.

AB - Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC.

M3 - Poster

T2 - European Pancreatic Club

Y2 - 9 June 2021 through 11 June 2021

ER -

Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

Abstract

Conference

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Projects

SRP65: SRP-Groeifinanciering: Molecular Portrait of Pancreatic Tumours: Veni, vidi, vici

FWOODYS12: De-convolution of tumour biology in the post-genomic era: focus on pancreatic cancer

Cite this