Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

Ellis Michiels; Yves Heremans; Ilse Rooman

Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

Ellis Michiels, Yves Heremans, Ilse Rooman

Research output: Unpublished contribution to conference › Poster

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC.

Original language	English
Publication status	Published - 29 Jun 2021
Event	EACR: cancer imaging - Duration: 29 Jun 2021 → 30 Jun 2021

Conference

Conference	EACR: cancer imaging
Period	29/06/21 → 30/06/21

1 Finished
1 Active

SRP65: SRP-Groeifinanciering: Molecular Portrait of Pancreatic Tumours: Veni, vidi, vici
Rooman, I. & De Grève, J.
1/03/19 → 31/12/26
Project: Fundamental
FWOODYS12: De-convolution of tumour biology in the post-genomic era: focus on pancreatic cancer
Rooman, I.
1/10/16 → 1/10/21
Project: Fundamental

Cite this

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title = "Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization",

abstract = "Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC. ",

author = "Ellis Michiels and Yves Heremans and Ilse Rooman",

year = "2021",

month = jun,

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language = "English",

note = "EACR: cancer imaging ; Conference date: 29-06-2021 Through 30-06-2021",

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TY - CONF

T1 - Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

AU - Michiels, Ellis

AU - Heremans, Yves

AU - Rooman, Ilse

PY - 2021/6/29

Y1 - 2021/6/29

N2 - Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC.

AB - Pancreatic ductal adenocarcinoma (PDAC) is known for its aggressive biology and lethality. Superior to conventional biomedical research models, the focus of this study is on the development and use of well-established patient-derived organoids (PDO)- and xenografts (PDX), mimicking the tumor as it is present in a human body. The models are extensively analysed using advanced spatial-omics analysis to investigate the ability to recapitulate two main molecular subtypes of PDAC.

M3 - Poster

T2 - EACR: cancer imaging

Y2 - 29 June 2021 through 30 June 2021

ER -

Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

Abstract

Conference

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Projects

SRP65: SRP-Groeifinanciering: Molecular Portrait of Pancreatic Tumours: Veni, vidi, vici

FWOODYS12: De-convolution of tumour biology in the post-genomic era: focus on pancreatic cancer

Cite this