TY - JOUR
T1 - Stability of Potential Renal Acid Load
AU - Versele, Vickà
AU - Clarys, Peter
AU - Deforche, Benedicte
AU - Lefevre, J.
AU - Mertens, Evelien
AU - Charlier, Ruben
AU - Knaeps, Sara
AU - Aerenhouts, Dirk
PY - 2020/2
Y1 - 2020/2
N2 - Aim: The potential renal acid load (PRAL) has been described in relation to different health outcomes. Outcomes over time and conclusions made are often based on baseline dietary intake values. However, to study reliable long-term associations, parameters calculated based on dietary intake data, such as PRAL, must be stable over time. Therefore, the aim of the present study was to assess the stability of PRAL and its components over a 10-year time period. Methods: PRAL values of three-day dietary intake data from 197 women and 373 men on two assessment moments (2002–2004 and 2012–2014) were calculated. Pearson correlation and intra-class correlation coefficients were used for assessing the stability of PRAL and its components. Level of agreement between the two assessment moments was estimated after splitting up subjects in quintiles of PRAL, calculating kappa values and changes of quintiles over time. Results: No significant differences in mean PRAL over time were found. Stability of PRAL and its components was low. Poor agreement between the first and second assessment was shown by low kappa values and change of most of the subjects to an adjacent and non-adjacent quintile after 10 years. Conclusions: Based on nutrition assessments carried out using three-day dietary records, stability of PRAL over a 10-year time period could not be confirmed, even though no significant difference between mean PRAL and its components over time was found. Therefore, interpretation of longitudinal outcomes based on PRAL and its component calculated at baseline should be interpreted with caution.
AB - Aim: The potential renal acid load (PRAL) has been described in relation to different health outcomes. Outcomes over time and conclusions made are often based on baseline dietary intake values. However, to study reliable long-term associations, parameters calculated based on dietary intake data, such as PRAL, must be stable over time. Therefore, the aim of the present study was to assess the stability of PRAL and its components over a 10-year time period. Methods: PRAL values of three-day dietary intake data from 197 women and 373 men on two assessment moments (2002–2004 and 2012–2014) were calculated. Pearson correlation and intra-class correlation coefficients were used for assessing the stability of PRAL and its components. Level of agreement between the two assessment moments was estimated after splitting up subjects in quintiles of PRAL, calculating kappa values and changes of quintiles over time. Results: No significant differences in mean PRAL over time were found. Stability of PRAL and its components was low. Poor agreement between the first and second assessment was shown by low kappa values and change of most of the subjects to an adjacent and non-adjacent quintile after 10 years. Conclusions: Based on nutrition assessments carried out using three-day dietary records, stability of PRAL over a 10-year time period could not be confirmed, even though no significant difference between mean PRAL and its components over time was found. Therefore, interpretation of longitudinal outcomes based on PRAL and its component calculated at baseline should be interpreted with caution.
UR - http://www.scopus.com/inward/record.url?scp=85046534903&partnerID=8YFLogxK
U2 - 10.1111/1747-0080.12432
DO - 10.1111/1747-0080.12432
M3 - Article
VL - 77
SP - 139
EP - 143
JO - Nutrition & dietetics: the journal of the Dietitians Association of Australia
JF - Nutrition & dietetics: the journal of the Dietitians Association of Australia
SN - 1446-6368
IS - 1
ER -