The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting P450 enzymes and c-jun N-terminal kinase activation

Kuo Du; David Williams; Mitchell R. Mcgill; Yuchao Xie; Anwar Farhood; Mathieu Vinken; Hartmut Jaeschke

The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting P450 enzymes and c-jun N-terminal kinase activation

Kuo Du, David Williams, Mitchell R. Mcgill, Yuchao Xie, Anwar Farhood, Mathieu Vinken, Hartmut Jaeschke

Toxicology, Dermato-cosmetology and Pharmacognosy

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

/

Original language	English
Pages (from-to)	484-491
Number of pages	8
Journal	Toxicology and Applied Pharmacology
Volume	273
Publication status	Published - 10 Dec 2013

Keywords

gap junction

FWOTM411: Elucidation of the role of connexin proteins in the control of hepatocellular homeostasis: development of a hepatocyte-based in vitro model for pre-clinical pharmaco-toxicological research
Vinken, M.
1/10/06 → 30/09/12
Project: Fundamental

Cite this

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title = "The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting P450 enzymes and c-jun N-terminal kinase activation",

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keywords = "gap junction",

author = "Kuo Du and David Williams and Mcgill, {Mitchell R.} and Yuchao Xie and Anwar Farhood and Mathieu Vinken and Hartmut Jaeschke",

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volume = "273",

pages = "484--491",

journal = "Toxicology and Applied Pharmacology",

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The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting P450 enzymes and c-jun N-terminal kinase activation. / Du, Kuo; Williams, David; Mcgill, Mitchell R.; Xie, Yuchao; Farhood, Anwar; Vinken, Mathieu; Jaeschke, Hartmut.

In: Toxicology and Applied Pharmacology, Vol. 273, 10.12.2013, p. 484-491.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting P450 enzymes and c-jun N-terminal kinase activation

AU - Du, Kuo

AU - Williams, David

AU - Mcgill, Mitchell R.

AU - Xie, Yuchao

AU - Farhood, Anwar

AU - Vinken, Mathieu

AU - Jaeschke, Hartmut

PY - 2013/12/10

Y1 - 2013/12/10

N2 - /

AB - /

KW - gap junction

M3 - Article

VL - 273

SP - 484

EP - 491

JO - Toxicology and Applied Pharmacology

JF - Toxicology and Applied Pharmacology

SN - 0041-008X

ER -

The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting P450 enzymes and c-jun N-terminal kinase activation

Abstract

Keywords

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Projects

FWOTM411: Elucidation of the role of connexin proteins in the control of hepatocellular homeostasis: development of a hepatocyte-based in vitro model for pre-clinical pharmaco-toxicological research

Cite this