The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1

Original language	English
Publication status	Unpublished - 2022
Event	GRC-Intriscially Disordered Proteins - Les Diablerets, Switzerland Duration: 26 Jun 2022 → 1 Jul 2022

Conference

Conference	GRC-Intriscially Disordered Proteins
Country/Territory	Switzerland
Period	26/06/22 → 1/07/22

Handle.net

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Research output

• 1 Article

• DNA binding and dimerization of the SOG1 NAC domain are functionally linked with its ability to undergo liquid-liquid phase separation.

  Mignon, K., Van der Eecken, R., Galle, M., Demulder, M., Van Lindt, J., De Veylder, L., De Greve, H. & Loris, R., 20 Jan 2026, In: Nucleic Acids Res.. 54, 2, 16 p., gkaf1522.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dimerization 100%
  • DNA Binding 100%
  • Phase Separation 100%
  • RNA 75%
  • Transcription Factor 50%

Activities

• 1 Member of PhD committee

• PhD defense Kim Mignon - Molecular basis of DNA recognition by Arabidopsis thaliana SOG1: the master regulator for DNA damage control in plants (Event)

  Mignon, K. (Speaker), Loris, R. (Supervisor), Messens, J. (Chair), Ruytinx, J. (Jury), Versées, W. (Jury), Ezerina, D. (Jury), Hadzi, S. (Jury) & Hendrix, J. (Jury)

  3 Dec 2025

  Activity: Membership › Member of PhD committee

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Demulder, M., Galle, M., Van Lindt, J., Van der Eecken, R., & Loris, R. (2022). The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1. Poster session presented at GRC-Intriscially Disordered Proteins, Switzerland.

Demulder, Manon ; Galle, Margot ; Van Lindt, Joris et al. / The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1. Poster session presented at GRC-Intriscially Disordered Proteins, Switzerland.

@conference{c5b50e7b176d478f8ec0c1d94a4ce478,

title = "The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1",

author = "Manon Demulder and Margot Galle and {Van Lindt}, Joris and {Van der Eecken}, Rani and Remy Loris",

year = "2022",

language = "English",

note = "GRC-Intriscially Disordered Proteins ; Conference date: 26-06-2022 Through 01-07-2022",

}

Demulder, M, Galle, M, Van Lindt, J, Van der Eecken, R & Loris, R 2022, 'The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1', GRC-Intriscially Disordered Proteins, Switzerland, 26/06/22 - 1/07/22.

The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1. / Demulder, Manon; Galle, Margot; Van Lindt, Joris et al.
2022. Poster session presented at GRC-Intriscially Disordered Proteins, Switzerland.

Research output: Unpublished contribution to conference › Poster

TY - CONF

T1 - The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1

AU - Demulder, Manon

AU - Galle, Margot

AU - Van Lindt, Joris

AU - Van der Eecken, Rani

AU - Loris, Remy

PY - 2022

Y1 - 2022

M3 - Poster

T2 - GRC-Intriscially Disordered Proteins

Y2 - 26 June 2022 through 1 July 2022

ER -

Demulder M, Galle M, Van Lindt J, Van der Eecken R, Loris R. The role of liquid-liquid phase separation (LLPS) in the regulatory mechanism of SOG1. 2022. Poster session presented at GRC-Intriscially Disordered Proteins, Switzerland.