The Usefulness of Evaluating Performance of Activities in Daily Living in the Diagnosis of Mild Cognitive Disorders

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The Assessment of Activities of Daily Living (ADL) is paramount to ensure the accurate early diagnosis of neurocognitive disorders. Unfortunately, the most common ADL tools are limited in their use in a diagnostic process. Hence, we set out to validate a tool to evaluate basic (b-), instrumental (i-), and advanced (a-) ADL called the Brussels Integrated Activities of Daily Living Inventory (BIA). At the geriatric day hospital of the University Hospital Brussels (Belgium) older persons (65+) labelled as Cognitively Healthy Persons (CHP) (n = 47), having a Mild Cognitive Impairment (MCI) (n = 39), and having Alzheimer's disease (AD) (n = 44) underwent a diagnostic procedure for neurocognitive disorders. Additionally, the BIA was carried out. An exploration using both (cumulative) logistic regressions and conditional inference trees aimed to select the most informative scales to discriminate between the HCP, persons with MCI and AD. The distinction between CHP and MCI and between MCI and AD was moderately successful with the i-ADLs, in addition to age. Therefore, it is advisable to conduct a multidomain assessment in which the i-ADL could serve as non-invasive and non-time-consuming screening, while the BIA might be useful for diagnostics and disease management.

Original languageEnglish
Article number11623
Number of pages13
JournalInternational Journal of Environmental Research and Public Health
Issue number21
Publication statusPublished - 5 Nov 2021

Bibliographical note

Funding Information:
Funding: This research was partly funded by the Research Foundation Willy Gepts from University Hospital Brussel, Belgium.

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Copyright 2022 Elsevier B.V., All rights reserved.


  • Activities of Daily Living
  • Aged
  • Aged, 80 and over
  • Alzheimer Disease/diagnosis
  • Cognition
  • Cognitive Dysfunction/diagnosis
  • Geriatric Assessment
  • Humans
  • Neuropsychological Tests


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