Tools and methods for expression of membrane proteins

Jan Steyaert; Nico Callewaert; Toon Laeremans; Els Pardon; Kristof Vandewalle; Katrien Claes

Tools and methods for expression of membrane proteins

Jan Steyaert (Inventor), Nico Callewaert (Inventor), Toon Laeremans (Inventor), Els Pardon (Inventor), Kristof Vandewalle (Inventor), Katrien Claes (Inventor)

Research output: Patent

Abstract

The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.

Original language	English
Patent number	US11479791
Publication status	Published - 2022

Cite this

@misc{8b4896b185b44fbfac32f15ca98075bb,

title = "Tools and methods for expression of membrane proteins",

abstract = "The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.",

author = "Jan Steyaert and Nico Callewaert and Toon Laeremans and Els Pardon and Kristof Vandewalle and Katrien Claes",

year = "2022",

language = "English",

type = "Patent",

note = "US11479791",

}

TY - PAT

T1 - Tools and methods for expression of membrane proteins

AU - Steyaert, Jan

AU - Callewaert, Nico

AU - Laeremans, Toon

AU - Pardon, Els

AU - Vandewalle, Kristof

AU - Claes, Katrien

PY - 2022

Y1 - 2022

N2 - The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.

AB - The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.

UR - http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=US11479791&F=0

M3 - Patent

M1 - US11479791

ER -

Tools and methods for expression of membrane proteins

Abstract

Other files and links

Fingerprint

IOF3011: GEAR: Nanobodies for Biotechnology and Health

Cite this

Tools and methods for expression of membrane proteins

Abstract

Other files and links

Fingerprint

Projects

IOF3011: GEAR: Nanobodies for Biotechnology and Health

Cite this