Where has my efficiency gone? Impacts of extracolumn peak broadening on performance, part 3: Tubing and detectors

Dwight R. Stoll, Ken Broeckhoven

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Abstract

Dispersion (broadening, or spreading) of analyte zones (peaks) outside of chromatography columns can seriously erode the resolution that good columns provide. In this installment, we focus on the contributions of dispersion in connecting tubing and detectors to the total level of extracolumn dispersion in a LC system.

Original languageEnglish
Pages (from-to)277–280
Number of pages4
JournalLC-GC Europe
Volume34
Issue number7
Publication statusPublished - Jul 2021

Keywords

  • Extracolumn Peak Broadening
  • PERFORMANCE

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