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Abstract
Intrinsic capacity, a crucial concept in healthy ageing, is defined by WHO as "the composite of all the physical and mental capacities that an individual can draw on at any point in time". Vitality capacity is considered the underlying physiological determinant of intrinsic capacity. To advance the measurement and monitoring of vitality capacity, a working group of WHO staff members and twenty experts representing six WHO regions was convened to discuss and clarify the attributes of vitality capacity and to develop a clear working definition of the concept. Potential biomarkers to measure vitality capacity were identified, and the following consensual working definition was developed: vitality capacity is a physiological state (due to normal or accelerated biological ageing processes) resulting from the interaction between multiple physiological systems, reflected in (the level of) energy and metabolism, neuromuscular function, and immune and stress response functions of the body.
Original language | English |
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Pages (from-to) | e789-e796 |
Number of pages | 8 |
Journal | The Lancet. Healthy longevity. |
Volume | 3 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2022 |
Bibliographical note
Funding Information:This Personal View was written in close collaboration with the Ageing and Health unit of WHO (Geneva, Switzerland) and the Frailty in Ageing research department of the Vrije Universiteit Brussel (Brussels, Belgium).
Publisher Copyright:
© 2022 World Health Organization
Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.
Keywords
- Humans
- Longevity/physiology
- Health Status
- Aging/physiology
- Healthy Aging
- World Health Organization
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Dive into the research topics of 'WHO working definition of vitality capacity for healthy longevity monitoring'. Together they form a unique fingerprint.Projects
- 1 Finished
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IRP12: Interdisciplinary Research Program: Gerontopole Brussels, centre of expertise for Gerontology at the Vrije Universiteit Brussel
Bautmans, I., Verté, D., Beyer, I., Petrovic, M., De Donder, L., De Witte, N., Kardol, T., Rossi, G., Dierckx, E., Deforche, B., Scafoglieri, A., De Hert, P., Jansen, B., Araujo de Carvalho, I. & Amuthavalli Thiyagarajan, J.
1/04/18 → 31/03/23
Project: Fundamental