INCREMENTAL CLINICAL VALUE AND QUANTITATIVE PERFORMANCE OF DUAL-LAYER DETECTOR DUAL-ENERGY CT.

Student thesis: Doctoral Thesis

Abstract

Dual-energy CT (DECT) is an innovative imaging technology which has been clinically available for about a decade. The goal of this thesis is to inform the readers of the basic physical principles of DECT, provide an overview of its current applications, present the findings of our research from investigating the spectral performance of one of the most recently introduced DECT systems (Dual-Layer or Spectral Detector CT), and present investigated potential applications of this technology.
Dual-Layer Detector DECT (dlDECT) is an approach that acquired dual-energy data at the level of the detector, by employing a dual-layer detector that acquired high- and low-energy photons at the bottom and top layer of the detector, respectively. Therefore, dual-energy imaging data is available with every scan. This makes dlDECT lend itself to improving characterization of incidental findings or opportunistic screening; a reasoning found in all the potential applications of dlDECT we investigated.
First, the advantages and limitations of DECT in general and dlDECT are investigated and discussed, to facilitate interpretation of the dual-energy reconstructions and help interpretation when faced with varying scan parameters and patients. Second, clinical applications are investigated. The focus is on clinically relevant applications that can solve diagnostic obstacles (metal or calcium blooming artifact reduction), and decrease patient mortality and morbidity (differentiate hemorrhage from iodine; bone mineral density assessment).
It is our hope that this information may provide practicing physicians/radiologists and researchers with new insights using this technology, and help make the most of this technology.
Date of Award20 May 2019
Original languageEnglish
Awarding Institution
  • Vrije Universiteit Brussel
SupervisorNico Buls (Promotor), Johan De Mey (Promotor), Anne Caterine Traegde Martinsen (Jury), Tim Leiner (Jury), Emmanuel Coche (Jury), Guy Nagels (Jury), Frederik Vandenbroucke (Jury), Gert Van Gompel (Jury) & Mark De Ridder (Jury)

Keywords

  • Dual-Layer Detector DECT
  • photons

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