International Union of Crystallography (IUCr) Congress and general Assembly 2011

Gerelateerde inhoud

• Onderzoeksoutput

• Vibrio cholerae ParE2 poisons DNA gyrase via a mechanism distinct from other gyrase inhibitors

  Onderzoeksoutput: Article › peer review

• Doc of prophage P1 is inhibited by its antitoxin partner Phd though fold complementation

  Onderzoeksoutput: Article › peer review

• Driving Forces of Gyrase Recognition by the Addiction Toxin

  Onderzoeksoutput: Article › peer review

• Energetics of structural transitions of the addiction antitoxin MazE

  Onderzoeksoutput: Article › peer review

• Intricate interactions within the ccd plasmid addiction system

  Onderzoeksoutput: Article › peer review

• Crystallization of the C-terminal domain of the addiction antidote CcdA in complex with its toxin CcdB.

  Onderzoeksoutput: Article › peer review

• Crystal Structure of CcdB, a Topoisomerase Poison from E. Coli

  Onderzoeksoutput: Article › peer review

• Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain

  Onderzoeksoutput: Article › peer review

• Structural and thermodynamic characterization of Vibrio fischeri CcdB

  Onderzoeksoutput: Article › peer review

• Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri

  Onderzoeksoutput: Article › peer review

• New bactericidal toxins homologous to ParE belonging to 3-component toxin-antitoxin systems in Escherichia coli O157:H7.

  Onderzoeksoutput: Article › peer review

• Crystal structure of the intrinsically flexible addiction antidote MazE.

  Onderzoeksoutput: Article › peer review

• Purification and crystallization of Vibrio fischeri CcdB and its complexes with fragments from gyrase and CcdA

  Onderzoeksoutput: Article › peer review

• Molecular basis of gyrase poisoning by the addiction toxin CcdB

  Onderzoeksoutput: Article › peer review

• Energetics of MazG structure in correlation with its regulatory function.

  Onderzoeksoutput: Article › peer review

• Crystallization of Doc and the Phd:Doc toxin-antitoxin complex

  Onderzoeksoutput: Article › peer review

• Crystallization of CcdB in complex with a GyrA fragment

  Onderzoeksoutput: Article › peer review

• Toxin-Antitoxin modules as bacterial metabolic stress managers.

  Onderzoeksoutput: Article › peer review

• Allostery and intrinsic disorder mediate transcription regulation by conditional co-operativity

  Onderzoeksoutput: Article › peer review

• Purification and crystallization of Phd, the antitoxin of the phd/doc operon

  Onderzoeksoutput: Article › peer review

• Crystallization of the Staphylococcus aureus MazF mRNA interferase

  Onderzoeksoutput: Article › peer review

• Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability and influence on interactions with DNA

  Onderzoeksoutput: Article › peer review

• Crystallisation of CcdB

  Onderzoeksoutput: Article › peer review

• projecten

• Infrastructuurplatform Biophysics.

  Project: Fundamenteel

• Structurele en biochemische karakterisering van de Staphylococcus aureus mazEF toxine-antitoxine module.

  Project: Fundamenteel

• Ontwikkeling Cryokristallografie

  Project: Fundamenteel

• Structurele biologie van een plasmide addictie systemen.

  Project: Fundamenteel

• Structurele basis van plasmide addictie en geprogrammeerde celdood in bacteriën.

  Project: Fundamenteel

• Werkingskrediet bj onderzoeksmandaat 1e jaar

  Project: Fundamenteel

• Functionele en genetische analyse van het ccd addictiesysteem.

  Project: Fundamenteel

• Structurele basis van plasmide addictie en geprogrammeerde celdood in bacteriën.

  Project: Fundamenteel

• Scripties/Masterproeven

• Karakterizatie van ccd-type plasmide addictie systemen

  Scriptie/Masterproef: Master's Thesis

• Zuivering en karakterizatie van het ccd toxine-antidote (TA) systeem van Vibrio fisherii

  Scriptie/Masterproef: Master's Thesis

• Mechanism of action of Doc from phage P1

  Scriptie/Masterproef: Master-after-master

• Zuivering en karakterizatie van het addictie toxine CcdB van Vibrio fisherii

  Scriptie/Masterproef: Master's Thesis

• Molecular interactions in the mazEFG toxin-antitoxin module from Escherichia coli

  Scriptie/Masterproef: Master's Thesis

• Interactie tussen CcdB en gyrase

  Scriptie/Masterproef: Master's Thesis