Structural dynamics in cellular communication

Gerelateerde inhoud

• projecten

• Moleculaire werkingsmechanismen van intrinsiek ontvouwen eiwitten.

  Project: Fundamenteel

• Dynamica van toxine-antitoxine stress respons netwerken: een interdisciplinaire computationele en in-vivo aanpak

  Project: Fundamenteel

• Regulatiemechanismen van bacteriële toxine-antitoxine modules

  Project: Fundamenteel

• Bacteriële toxine-antitoxine systemen als drug targets.

  Project: Fundamenteel

• Onderzoeksoutput

• Doc of prophage P1 is inhibited by its antitoxin partner Phd though fold complementation

  Onderzoeksoutput: Article › peer review

• The Intrinsically Disordered Domain of the Antitoxin Phd Chaperones the Toxin Doc Against Irreversible Inactivation and Misfolding

  Onderzoeksoutput: Article › peer review

• The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu

  Onderzoeksoutput: Article › peer review

• Driving Forces of Gyrase Recognition by the Addiction Toxin

  Onderzoeksoutput: Article › peer review

• Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics.

  Onderzoeksoutput: Article › peer review

• Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain

  Onderzoeksoutput: Article › peer review

• Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability and influence on interactions with DNA

  Onderzoeksoutput: Article › peer review

• Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding

  Onderzoeksoutput: Article › peer review

• Energetic basis of uncoupling folding from binding for an intrinsically disordered protein

  Onderzoeksoutput: Article › peer review

• Disorder- and Dynamics-Based Regulatory Mechanisms in Toxin-Antitoxin Modules.

  Onderzoeksoutput: Article › peer review