Cellulaire en Moleculaire Immunologie

2023

Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis

De Muynck, K., Vanderborght, B., De Ponti, F. F., Gijbels, E., Van Welden, S., Guilliams, M., Scott, C. L., Beschin, A., Vinken, M., Lefere, S., Geerts, A., Verhelst, X., Van Vlierberghe, H. & Devisscher, L., 11 jan 2023, (Accepted/In press) In: The American Journal of Pathology.

Onderzoeksoutput: Article › peer review

Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting

Erreni, M., D'Autilia, F., Avigni, R., Bolli, E., Arnouk, S. M., Movahedi, K., Debie, P., Anselmo, A., Parente, R., Vincke, C., van Leeuwen, F. W. B., Allavena, P., Garlanda, C., Mantovani, A., Doni, A., Hernot, S. & Van Ginderachter, J. A., 1 jan 2023, In: Theranostics. 13, 1, blz. 355-373 19 blz.

Onderzoeksoutput: Article › peer review

2022

AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model

Marino, M., Zhou, L., Rincon, M. Y., Callaerts-Vegh, Z., Verhaert, J., Wahis, J., Creemers, E., Yshii, L., Wierda, K., Saito, T., Marneffe, C., Voytyuk, I., Wouters, Y., Dewilde, M., Duqué, S. I., Vincke, C., Levites, Y., Golde, T. E., Saido, T. C., Muyldermans, S. & 3 anderen, Liston, A., De Strooper, B. & Holt, M. G., 7 apr 2022, In: EMBO Molecular Medicine. 14, 4, e09824.

Onderzoeksoutput: Article › peer review

Open Access

Bestand

5 Citaten (Scopus)

8 Downloads (Pure)

A combination of ontogeny and environment drives macrophage identity across brain regions

Van Hove, H., 2022, Brussel: Crazy Copy Center Productions. 187 blz.

Onderzoeksoutput: PhD Thesis

African Trypanosomiasis

Magez, S., Nguyen, H. T. T., Pinto Torres, J. E. & Radwanska, M., 25 sep 2022, Textbook of Parasitic Zoonoses. Chandra Parija, S. & Chaudhury, A. (redactie). SpringerLink

Onderzoeksoutput: Chapter › Research › peer review

Anti-MIF nanobodies as a novel tool to improve cancer therapy

Mora Barthelmess, R., Stijlemans, B. & Van Ginderachter, J., 19 sep 2022, (Unpublished).

Onderzoeksoutput: Poster

Bestand

9 Downloads (Pure)

BCG-mediated protection against M. tuberculosis is sustained post-malaria infection independent of parasite virulence

Tangie, E., Waters, A., Hsu, N-J., Fisher, M., Magez, S., Jacobs, M. & Keeton, R., feb 2022, In: Immunology. 165, 2, blz. 219-233 15 blz.

Onderzoeksoutput: Article › peer review

Open Access

1 Citaat (Scopus)

Deciphering the structure and function of select membrane associated proteins in haemo-protozoan parasites

Kariuki, C. K., 2022, 251 blz.

Onderzoeksoutput: PhD Thesis

Open Access

Bestand

39 Downloads (Pure)

Dendritic Cell-Based Immunotherapy in Multiple Myeloma: Challenges, Opportunities, and Future Directions

Verheye, E., Melgar, J. B., Deschoemaeker, S., Raes, G., Maes, A., De Bruyne, E., Menu, E., Vanderkerken, K., Laoui, D. & De Veirman, K., 14 jan 2022, In: International Journal of Molecular Sciences. 23, 2, 904.

Onderzoeksoutput: Scientific review › peer review

Open Access

8 Citaten (Scopus)

Dendritic Cell Vaccines: A Promising Approach in the Fight against Ovarian Cancer

Caro, A., Deschoemaeker, S., Allonsius, L., Coosemans, A. & Laoui, D., 21 aug 2022, In: Cancers. 14, 16, 29 blz., 4037.

Onderzoeksoutput: Article › peer review

Open Access

Dendritische cellen als immunotherapie voor multipel myeloom

Verheye, E., De Beule, N., Laoui, D. & De Veirman, K., 2022, In: OncoHemato. 16, 3, blz. 35-38 4 blz.

Onderzoeksoutput: Article › peer review

Detrimental Effect of Trypanosoma brucei brucei Infection on Memory B Cells and Host Ability to Recall Protective B-cell Responses

Moon, S., Janssens, I., Kim, K. H., Stijlemans, B., Magez, S. & Radwanska, M., 1 apr 2022, In: The Journal of Infectious Diseases. 226, 3, blz. 528-540 13 blz.

Onderzoeksoutput: Article › peer review

3 Citaten (Scopus)

Development of a kit for 68GA-labeling of single-domain antibody diagnostics for molecular imaging

Baudhuin, H. V., 2022, Brussel: Crazy Copy Center Productions. 188 blz.

Onderzoeksoutput: PhD Thesis

Open Access

Bestand

103 Downloads (Pure)

Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

De Vlaminck, K., Van Hove, H., Kancheva, D., Scheyltjens, I., Pombo Antunes, A. R., Bastos, J., Vara-Perez, M., Ali, L., Mampay, M., Deneyer, L., Miranda, J. F., Cai, R., Bouwens, L., De Bundel, D., Caljon, G., Stijlemans, B., Massie, A., Van Ginderachter, J. A., Vandenbroucke, R. E. & Movahedi, K., 8 nov 2022, In: Immunity. 55, 11, blz. 2085-2102.e9 18 blz.

Onderzoeksoutput: Article › peer review

2 Citaten (Scopus)

Early Kupffer cell depletion does not affect hepatocellular carcinoma progression in mice

Van derborght, B., De Muynck, K., Scott, C., Beschin, A., Guilliams, M., Van Vlierberghe, H. & Devisscher, L., jul 2022, In: Journal of Hepatology. 77, blz. S655-S655

Onderzoeksoutput: Meeting abstract (Journal)

External Validation of a Breath-Based Prediction Model for Malignant Pleural Mesothelioma

Janssens, E., Schillebeeckx, E., Zwijsen, K., Raskin, J., Cleemput, J. V., Surmont, V. F., Nackaerts, K., Marcq, E., Meerbeeck, J. P. V. & Lamote, K., 29 jun 2022, In: Cancers. 14, 13, 10 blz., 3182.

Onderzoeksoutput: Article › peer review

Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria

An, H., Qian, C., Li, J., Tian, X., Feng, J., Hu, J., Fang, Y., Jiao, F., Zeng, Y., Huang, X., Meng, X., Liu, X., Lin, X., Zeng, Z., Guilliams, M., Beschin, A., Chen, Y., Wu, Y., Wang, J., Oggioni, M. R. & 8 anderen, Leong, J., Veening, J-W., Deng, H., Zhang, R., Wang, H., Wu, J., Cui, Y. & Zhang, J-R., 4 apr 2022, In: The Journal of Experimental Medicine. 219, 4, 30 blz., e20212032.

Onderzoeksoutput: Article › peer review

Open Access

GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide

Parik, S., Fernández-García, J., Lodi, F., De Vlaminck, K., Derweduwe, M., De Vleeschouwer, S., Sciot, R., Geens, W., Weng, L., Bosisio, F. M., Bergers, G., Duerinck, J., De Smet, F., Lambrechts, D., Van Ginderachter, J. A. & Fendt, S-M., 23 sep 2022, In: Frontiers in Oncology. 12, 17 blz., 988872.

Onderzoeksoutput: Article › peer review

Open Access

Heterogeneity and function of macrophages in the breast during homeostasis and cancer

Hadadi, E., Deschoemaeker, S., Vicente Venegas, G. & Laoui, D., 2022, PaOne, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease. Elsevier, blz. 149-182 (International Review of Cell and Molecular Biology).

Onderzoeksoutput: Chapter › Research › peer review

1 Citaat (Scopus)

Humoral and Cellular Immune Responses against SARS-CoV-2 after Third Dose BNT162b2 following Double-Dose Vaccination with BNT162b2 versus ChAdOx1 in Patients with Cancer

Debie, Y., Audenaerde, J. R. M. V., Vandamme, T., Croes, L., Teuwen, L-A., Verbruggen, L., Vanhoutte, G., Marcq, E., Verheggen, L., Blon, D. L., Peeters, B., Goossens, M. E., Pannus, P., Ariën, K. K., Anguille, S., Janssens, A., Prenen, H., Smits, E. L. J., Vulsteke, C., Lion, E. & 2 anderen, Peeters, M. & Dam, P. A. V., 15 dec 2022, In: Clinical Cancer Research. 2023, blz. OF1–OF12 12 blz.

Onderzoeksoutput: Article › peer review

Imaging and therapeutic targeting of the tumor immune microenvironment with biologics

Arnouk, S., De Groof, T. & Van Ginderachter, J., mei 2022, In: Advanced Drug Delivery Reviews. 184, 114239.

Onderzoeksoutput: Scientific review › peer review

Open Access

Infection history imprints long-lasting changes to Kupffer cells

Musrati, M., Stijlemans, B., Azouz, A., Kancheva, D., Mesbahi, S., Lebegge, E., De Vlaminck, K., Hadadi, E., Elkrim, Y., De Baetselier, P., Goriely, S., Movahedi, K. & Van Ginderachter, J., 2022, (Unpublished).

Onderzoeksoutput: Poster

Infection history imprints long-lasting changes to Kupffer cells

Musrati, M., Stijlemans, B., Kancheva, D., Mesbahi, S., Lebegge, E., De Vlaminck, K., Elkrim, Y., De Baetselier, P., Movahedi, K. & Van Ginderachter, J., 19 sep 2022, (Unpublished).

Onderzoeksoutput: Poster

In Vivo Identification of Adducts from the New Hypoxia-Activated Prodrug CP-506 Using DNA Adductomics

Solivio, M. J., Stornetta, A., Gilissen, J., Villalta, P. W., Deschoemaeker, S., Heyerick, A., Dubois, L. & Balbo, S., 21 feb 2022, In: Chemical Research in Toxicology. 35, 2, blz. 275-282 8 blz.

Onderzoeksoutput: Article › peer review

3 Citaten (Scopus)

In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using 68 Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages

Varasteh, Z., Braeuer, M., Mohanta, S., Steinsiek, A-L., Habenicht, A., Omidvari, N., Topping, G. J., Rischpler, C., Weber, W. A., Sager, H. B., Raes, G., Hernot, S. & Schwaiger, M., 25 apr 2022, In: Frontiers in Cardiovascular Medicine. 9, 10 blz., 889963.

Onderzoeksoutput: Article › peer review

Open Access

Bestand

9 Downloads (Pure)

Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment

Kiss, M., Lebegge, E., Murgaski, A., Van Damme, H., Kancheva, D., Brughmans, J., Scheyltjens, I., Talebi, A., Awad, R. M., Elkrim, Y., Bardet, P. M. R., Arnouk, S. M., Goyvaerts, C., Swinnen, J., Nana, F. A., Van Ginderachter, J. A. & Laoui, D., 1 dec 2022, In: Frontiers in Immunology. 13, 14 blz., 1003975.

Onderzoeksoutput: Article › peer review

Open Access

Lipocalin-2 (Lcn-2) as a potential target in triple negative breast carcinoma

Zivalj, M., Van Ginderachter, J., Stijlemans, B. & Vincke, C., 18 okt 2022.

Onderzoeksoutput: Poster

Lipocalin-2 (Lcn-2) as a potential target in triple negative breast carcinoma

Zivalj, M., Van Ginderachter, J., Stijlemans, B. & Vincke, C., 19 sep 2022.

Onderzoeksoutput: Poster

Lymphatic mapping and surgical lymphadenectomy guidance using fluorescently labeled mannose-receptor-targeting nanobodies

Mateusiak, L., Debacker, J., Debie, P., Declerck, N., van Willigen, D. M., Raes, G., Mottrie, A., De Sutter, P., van Leeuwen, F. W. B., de Rooster, H. & Hernot, S., 18 mrt 2022.

Onderzoeksoutput: Unpublished abstract

Nanobodies: From Serendipitous Discovery of Heavy Chain-Only Antibodies in Camelids to a Wide Range of Useful Applications

Ji, F., Ren, J., Vincke, C., Jia, L. & Muyldermans, S., 2022, In: Methods in Molecular Biology: Experimental Cholestasis Research . 2446, blz. 3-17 15 blz.

Onderzoeksoutput: Article › peer review

1 Citaat (Scopus)

Nanobodies as binding-chaperones stabilize the recombinant Bombyx mori acetylcholinesterase and protect the enzyme activity in pesticide detection

Cai, J., Romao, E., Li, J., Li, L., Wang, Z., Li, Y., Yang, J., Shen, Y., Xu, Z., Muyldermans, S. & Wang, H., apr 2022, In: Enzyme and Microbial Technology. 155, 109992.

Onderzoeksoutput: Article › peer review

Nanobodies for the Early Detection of Ovarian Cancer

Tran, L-H., Graulus, G-J., Vincke, C., Smiejkowska, N., Kindt, A., Devoogdt, N., Muyldermans, S., Adriaensens, P. & Guedens, W., 8 nov 2022, In: International Journal of Molecular Sciences. 23, 22, 13687.

Onderzoeksoutput: Article › peer review

Open Access

Neutralizing Dromedary-Derived Nanobodies Against BotI-Like Toxin From the Most Hazardous Scorpion Venom in the Middle East and North Africa Region

Ben Abderrazek, R., Ksouri, A., Idoudi, F., Dhaouadi, S., Hamdi, E., Vincke, C., Farah, A., Benlasfar, Z., Majdoub, H., El Ayeb, M., Muyldermans, S. & Bouhaouala-Zahar, B., 19 apr 2022, In: Frontiers in Immunology. 13, 13 blz., 863012.

Onderzoeksoutput: Article › peer review

Open Access

2 Citaten (Scopus)

Optimization of the Solvent and In Vivo Administration Route of Auranofin in a Syngeneic Non-Small Cell Lung Cancer and Glioblastoma Mouse Model

Boullosa, L. F., Loenhout, J. V., Hermans, C., Lau, H. W., Merlin, C., Marcq, E., Takhsha, F. S., Martinet, W., Meyer, G. R. Y. D., Lardon, F., Smits, E. L. J. & Deben, C., 9 dec 2022, In: Pharmaceutics. 14, 12, 18 blz., 2761.

Onderzoeksoutput: Article › peer review

Recent Advances of Immune Checkpoint Inhibition and Potential for (Combined) TIGIT Blockade as a New Strategy for Malignant Pleural Mesothelioma

Rovers, S., Janssens, A., Raskin, J., Pauwels, P., Meerbeeck, J. P. V., Smits, E. & Marcq, E., 14 mrt 2022, In: Biomedicines. 10, 3, 17 blz., 673.

Onderzoeksoutput: Article › peer review

1 Citaat (Scopus)

Recent progress in diagnosis and treatment of Human African Trypanosomiasis has made the elimination of this disease a realistic target by 2030

Álvarez-Rodríguez, A., Jin, B-K., Radwanska, M. & Magez, S., 3 nov 2022, In: Frontiers in Medicine. 9, 12 blz., 1037094.

Onderzoeksoutput: Article › peer review

Retrospective in silico mutation profiling of SARS-CoV-2 structural proteins circulating in Uganda by July 2021: Towards refinement of COVID-19 disease vaccines, diagnostics, and therapeutics

Odongo, S., Okella, H., Ndekezi, C., Okee, M., Namayanja, M., Mujuni, B., Sterckx, Y. G. J., Kizito, D., Radwanska, M., Magez, S., Ikwap, K., Mwiine, F. N., Lutwama, J. J. & Ibingira, C., 22 dec 2022, In: PLOS ONE. 17, 12, 21 blz., e0279428.

Onderzoeksoutput: Article › peer review

Sensitive Protein Detection Using Site-Specifically Oligonucleotide-Conjugated Nanobodies

Al-Amin, R. A., Muthelo, P. M., Abdurakhmanov, E., Vincke, C., Amin, S. P., Muyldermans, S., Danielson, U. H. & Landegren, U., 19 jul 2022, In: Analytical Chemistry. 94, 28, blz. 10054-10061 8 blz.

Onderzoeksoutput: Article › peer review

Open Access

Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues

Scheyltjens, I., Van Hove, H., De Vlaminck, K., Kancheva, D., Bastos, J., Vara-Pérez, M., Pombo Antunes, A. R., Martens, L., Scott, C. L., Van Ginderachter, J. A., Saeys, Y., Guilliams, M., Vandamme, N. & Movahedi, K., okt 2022, In: Nature Protocols. 17, 10, blz. 2354-2388 35 blz.

Onderzoeksoutput: Article › peer review

1 Citaat (Scopus)

Targeting the tsetse-trypanosome interplay using genetically engineered Sodalis glossinidius

De Vooght, L., De Ridder, K., Hussain, S., Stijlemans, B., De Baetselier, P., Caljon, G. & Van Den Abbeele, J., 10 mrt 2022, In: PLoS Pathogens. 18, 3, blz. e1010376 e1010376.

Onderzoeksoutput: Article › peer review

Open Access