Cellulaire en Moleculaire Immunologie

Onderzoeksoutput

Onderzoeksoutput per jaar 1970 2021

• 42970 Citaties
• 98 h-Index
• 672 Article
• 64 Poster
• 52 Meeting abstract (Book)
• 35 Chapter
• 103 Meer
  • 25 Patent
  • 21 Scientific review
  • 17 Meeting abstract (Journal)
  • 17 Conference paper
  • 10 Unpublished abstract
  • 7 Book
  • 3 Editorial
  • 1 Other report
  • 1 Book/Film/Article review
  • 1 PhD Thesis

Onderzoeksoutput per jaar

Onderzoeksoutput per jaar

Zoekresultaten

• 2021

  68Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers

  Baudhuin, H., Cousaert, J., Vanwolleghem, P., Raes, G., Caveliers, V., Keyaerts, M., Lahoutte, T. & Xavier, C., 1 jan 2021, In : Pharmaceuticals. 14, 5, 16 blz., 448.

  Onderzoeksoutput: Article

  • 1,4,7-triazacyclononane-N,N',N''-triacetic acid 100%
  • Ascorbic Acid 42%
  • Ethanol 36%
  • 2,5-dihydroxybenzoic acid 24%
  • Single-Domain Antibodies 21%

• Comprehensive genomic analysis reveals virulence factors and antibiotic resistance genes in Pantoea agglomerans KM1, a potential opportunistic pathogen

  Guevarra, R. B., Magez, S., Peeters, E., Chung, M. S., Kim, K. H. & Radwanska, M., jan 2021, In : PLOS ONE. 16, 1, 27 blz., e0239792.

  Onderzoeksoutput: Article

  • Pantoea 100%
  • Virulence Factors 62%
  • Microbial Drug Resistance 60%
  • Genome 41%
  • Interleukin-10 40%
  2 Citaten (Scopus)

• Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality

  Baudhuin, H., Puttemans, J., Hanssens, H., Vanwolleghem, P., Hernot, S., Raes, G., Xavier, C., Lahoutte, T. & Debie, P., mei 2021, In : Pharmaceuticals. 14, 5, 19 blz., 407.

  Onderzoeksoutput: Article

  • Single-Domain Antibodies 100%
  • Chelating Agents 73%
  • Pentetic Acid 69%
  • 1,4,7-triazacyclononane-N,N',N''-triacetic acid 46%
  • Anions 28%

• Development and Characterization of Nanobodies Targeting the Kupffer Cell

  Zheng, F., Zhou, J., Ouyang, Z., Zhang, J., Wang, X., Muyldermans, S., Van Ginderachter, J., Devoogdt, N., Wen, Y., Schoonooghe, S. & Raes, G., 22 feb 2021, In : Frontiers in Immunology. 12, 12 blz., 641819.

  Onderzoeksoutput: Article

  • Single-Domain Antibodies 100%
  • Kupffer Cells 79%
  • Kupffer cell receptor 32%
  • Epitopes 28%
  • New World Camelids 12%
  1 Citaat (Scopus)

• Factors associated with adherence to COVID-19 prevention measures in the Democratic Republic of the Congo (DRC): results of an online survey

  Ditekemena, J. D., Nkamba, D. M., Muhindo, H. M., Siewe, J. N. F., Luhata, C., Van den Bergh, R., Tshefu Kitoto, A., Van Damme, W., Muyembe, J. J. & Colebunders, R., 18 jan 2021, In : BMJ Open. 11, 1, blz. e043356 9 blz., e043356.

  Onderzoeksoutput: Article

  • Democratic Republic of the Congo 100%
  • Hand Disinfection 15%
  • Masks 12%
  • Health Personnel 10%
  • Students 8%
  5 Citaten (Scopus)

• Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade

  Awad, R. M., Lecocq, Q., Zeven, K., Ertveldt, T., De Beck, L., Ceuppens, H., Broos, K., De Vlaeminck, Y., Goyvaerts, C., Verdonck, M., Raes, G., Van Parys, A., Cauwels, A., Keyaerts, M., Devoogdt, N. & Breckpot, K., 10 sep 2021, In : Molecular Therapy: Methods & Clinical Development. 22, 9, blz. 172-182 11 blz., 10.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Single-Domain Antibodies 100%
  • avelumab 60%
  • T-Cell Antigen Receptor 33%
  • Melanoma 27%
  • Genes 26%
  11 Downloads (Pure)

• Gene-based delivery of human PD-L1 single domain antibody formats for immune checkpoint blockade

  Awad, R. M., Lecocq, Q., Zeven, K., Ertveldt, T., De Beck, L., Ceuppens, H., Broos, K., De Vlaeminck, Y., Goyvaerts, C., Verdonck, M., Raes, G., Van Parys, A., Cauwels, A., Keyaerts, M., Devoogdt, N. & Breckpot, K., 22 feb 2021.

  Onderzoeksoutput: Poster

  Bestand

  • Single-Domain Antibodies 100%
  • avelumab 40%
  • Immunoglobulin Fragments 28%
  • Genes 26%
  • T-Cell Antigen Receptor 22%
  19 Downloads (Pure)

• IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D

  Kiss, M., Vande Walle, L., Saavedra, P. H. V., Lebegge, E., Van Damme, H., Murgaski, A., Qian, J., Ehling, M., Pretto, S., Bolli, E., Keirsse, J., Bardet, P. M. R., Arnouk, S. M., Elkrim, Y., Schmoetten, M., Brughmans, J., Debraekeleer, A., Fossoul, A., Boon, L., Raes, G. & 8 anderen, van Loo, G., Lambrechts, D., Mazzone, M., Beschin, A., Wullaert, A., Lamkanfi, M., Van Ginderachter, J. A. & Laoui, D., mrt 2021, In : Cancer Immunology Research. 9, 3, blz. 309-323 15 blz.

  Onderzoeksoutput: Article

  • Inflammasomes 100%
  • Tumor Microenvironment 86%
  • Neoplasms 26%
  • T-Lymphocytes 25%
  • Macrophages 21%
  4 Citaten (Scopus)

• Immunogenicity Risk Profile of Nanobodies

  Ackaert, C., Smiejkowska, N., Xavier, C., Sterckx, Y. G. J., Denies, S., Stijlemans, B., Elkrim, Y., Devoogdt, N., Caveliers, V., Lahoutte, T., Muyldermans, S., Breckpot, K. & Keyaerts, M., 9 mrt 2021, In : Frontiers in Immunology. 12, 15 blz., 632687.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Single-Domain Antibodies 100%
  • human ERBB2 protein 27%
  • Dendritic Cells 19%
  • Antibodies 18%
  • Pharmacokinetics 16%
  9 Citaten (Scopus)

  62 Downloads (Pure)

• Improving the yield of recalcitrant Nanobodies® by simple modifications to the standard protocol

  Kariuki, C. K. & Magez, S., 12 mei 2021, In : Protein Expression and Purification. 185, 9 blz., 105906.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Single-Domain Antibodies 100%
  • Escherichia coli 27%
  • imidazoleacetic acid 22%
  • Periplasm 17%
  • Solubility 13%
  98 Downloads (Pure)

• Lyophilization of NOTA-sdAbs: First step towards a cold diagnostic kit for 68Ga-labeling

  Baudhuin, H., Van Bockstal, P-J., De Beer, T., Vaneycken, I., Bridoux, J., Raes, G., Caveliers, V., Keyaerts, M., Devoogdt, N., Lahoutte, T. & Xavier, C., sep 2021, In : European Journal of Pharmaceutics and Biopharmaceutics. 166, blz. 194-204 11 blz.

  Onderzoeksoutput: Article

  • 1,4,7-triazacyclononane-N,N',N''-triacetic acid 100%
  • Single-Domain Antibodies 86%
  • Freeze Drying 73%
  • Immunoglobulin Fragments 73%
  • Cold Temperature 51%

• Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation

  Virga, F., Cappellesso, F., Stijlemans, B., Henze, A-T., Trotta, R., Van Audenaerde, J., Mirchandani, A. S., Sanchez-Garcia, M. A., Vandewalle, J., Orso, F., Riera-Domingo, C., Griffa, A., Ivan, C., Smits, E., Laoui, D., Martelli, F., Langouche, L., Van den Berghe, G., Feron, O., Ghesquière, B. & 8 anderen, Prenen, H., Libert, C., Walmsley, S. R., Corbet, C., Van Ginderachter, J. A., Ivan, M., Taverna, D. & Mazzone, M., 7 mei 2021, In : Science Advances. 7, 19, eabf0466.

  Onderzoeksoutput: Article

  • MicroRNAs 100%
  • Macrophages 81%
  • Inflammation 68%
  • Monocytes 47%
  • Sepsis 46%
  1 Citaat (Scopus)

• Monocytic myeloid-derived suppressor cells home to tumor-draining lymph nodes via CCR2 and locally modulate the immune response

  Lahmar, Q., Schouppe, E., Morias, Y., Van Overmeire, E., De Baetselier, P., Movahedi, K., Laoui, D., Sarukhan, A. & Van Ginderachter, J. A., apr 2021, In : Cellular Immunology. 362, 8 blz., 104296.

  Onderzoeksoutput: Article

  • Myeloid-Derived Suppressor Cells 100%
  • Lymph Nodes 52%
  • Tumor Microenvironment 31%
  • Neoplasms 23%
  • T-Lymphocytes 18%
  2 Citaten (Scopus)

• Myeloid tumor necrosis factor and heme oxygenase-1 regulate the progression of colorectal liver metastases during hepatic ischemia-reperfusion

  Germanova, D., Keirsse, J., Köhler, A., Hastir, J-F., Demetter, P., Delbauve, S., Elkrim, Y., Verset, L., Larbanoix, L., Preyat, N., Laurent, S., Nedospasov, S., Donckier, V., Van Ginderachter, J. A. & Flamand, V., 1 mrt 2021, In : International Journal of Cancer. 148, 5, blz. 1276-1288 13 blz.

  Onderzoeksoutput: Article

  • Heme Oxygenase-1 100%
  • Reperfusion 74%
  • Ischemia 63%
  • Tumor Necrosis Factor-alpha 60%
  • Neoplasm Metastasis 52%
  3 Citaten (Scopus)

• Phase I trial of 131I-GMIB-Anti-HER2-VHH1, a new promising candidate for HER2-targeted radionuclide therapy in breast cancer patients

  D'Huyvetter, M., De Vos, J., Caveliers, V., Vaneycken, I., Heemskerk, J., Duhoux, F. P., Fontaine, C., Vanhoeij, M., Windhorst, A. D., van der Aa, F., Hendrikse, N. H., Eersels, J. L. E., Everaert, H., Gykiere, P., Devoogdt, N., Raes, G., Lahoutte, T. & Keyaerts, M., 1 aug 2021, In : Journal of Nuclear Medicine. 62, 8, blz. 1097-1105 9 blz.

  Onderzoeksoutput: Article

  • Radioisotopes 100%
  • Breast Neoplasms 62%
  • Kidney 52%
  • Single Photon Emission Computed Tomography Computed Tomography 51%
  • N-succinimidyl 4-guanidinomethyl-3-iodobenzoate 43%

• Role of circadian rhythm disorders in EMT and tumor-immune interactions in endocrine-related cancers.

  Hadadi, E. & Acloque, H., 28 feb 2021, In : Endocrine-Related Cancer. 28, 2, blz. R67–R80 14 blz.

  Onderzoeksoutput: Article

  • Chronobiology Disorders 100%
  • Endocrine Gland Neoplasms 97%
  • Epithelial-Mesenchymal Transition 65%
  • Plant Physiological Phenomena 58%
  • Prostatic Neoplasms 48%
  4 Citaten (Scopus)

• Salivarian Trypanosomes Have Adopted Intricate Host-Pathogen Interaction Mechanisms That Ensure Survival in Plain Sight of the Adaptive Immune System

  Magez, S., Pinto Torres, J. E., Oh, S. & Radwanska, M., 31 mei 2021, In : PLoS Pathogens. 10, 6, 18 blz., 679.

  Onderzoeksoutput: Article

  • Host-Pathogen Interactions 100%
  • Trypanosoma 95%
  • Immune System 60%
  • Survival 42%
  • Trypanosomiasis 37%
  1 Citaat (Scopus)

• Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

  Pombo Antunes, A. R., Scheyltjens, I., Lodi, F., Messiaen, J., Antoranz, A., Duerinck, J., Kancheva, D., Martens, L., De Vlaminck, K., Van Hove, H., Kjølner Hansen, S. S., Bosisio, F. M., Van der Borght, K., De Vleeschouwer, S., Sciot, R., Bouwens, L., Verfaillie, M., Vandamme, N., Vandenbroucke, R. E., De Wever, O. & 8 anderen, Saeys, Y., Guilliams, M., Gysemans, C., Neyns, B., De Smet, F., Lambrechts, D., Van Ginderachter, J. A. & Movahedi, K., apr 2021, In : Nature Neuroscience. 24, 4, blz. 595-610 16 blz.

  Onderzoeksoutput: Article

  • Myeloid Cells 100%
  • Glioblastoma 97%
  • Macrophages 68%
  • Microglia 33%
  • Neoplasms 31%
  15 Citaten (Scopus)

• Targeted Repolarization of Tumor-Associated Macrophages via Imidazoquinoline-Linked Nanobodies

  Bolli, E., Scherger, M., Arnouk, S., Pombo Antunes, A. R., Straßburger, D., Urschbach, M., Stickdorn, J., De Vlaminck, K., Movahedi, K., Räder, H. J., Hernot, S., Besenius, P., Van Ginderachter, J. & Nuhn, L., 19 mei 2021, In : Advanced Science. 8, 10, 12 blz., 2004574.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Macrophages 100%
  • Single-Domain Antibodies 89%
  • macrophages 85%
  • Tumors 61%
  • tumors 57%
  2 Citaten (Scopus)

  31 Downloads (Pure)

• Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

  Van Damme, H., Dombrecht, B., Kiss, M., Roose, H., Allen, E., Van Overmeire, E., Kancheva, D., Martens, L., Murgaski, A., Bardet, P., Blancke, G., Jans, M., Bolli, E., Martins, M. S., Elkrim, Y., Dooley, J., Boon, L., Schwarze, J. K., Tacke, F., Movahedi, K. & 9 anderen, Vandamme, N., Neyns, B., Ocak, S., Scheyltjens, I., Vereecke, L., Nana, F. A., Merchiers, P., Laoui, D. & Van Ginderachter, J. A., feb 2021, In : Journal for immunotherapy of cancer. 9, 2, 16 blz., e001749.

  Onderzoeksoutput: Article

  • Programmed Cell Death 1 Receptor 100%
  • Regulatory T-Lymphocytes 67%
  • Antibody-Dependent Cell Cytotoxicity 65%
  • Immunity 55%
  • Single-Domain Antibodies 28%
  5 Citaten (Scopus)

• Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor

  Van Campenhout, R., Muyldermans, S., Vinken, M., Devoogdt, N. & De Groof, T., 6 jan 2021, In : Biomolecules. 11, 1, blz. 1-19 19 blz., 63.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Single-Domain Antibodies 100%
  • Cell membranes 89%
  • Membrane Transport Proteins 81%
  • Staphylococcal Protein A 76%
  • Blood Proteins 58%
  4 Citaten (Scopus)

  86 Downloads (Pure)

• The therapeutic potential of Actinium-225-labeled CS1-specific single-domain antibodies for the treatment of Multiple Myeloma

  De Veirman, K., Puttemans, J., Krasniqi, A., Hanssens, H., Romao, E., Vlummens, P., Breckpot, K., Hose, D., Bruchertseifer, F., Morgenstern, A., D'Huyvetter, M. & Devoogdt, N., 8 sep 2021, blz. 79-79. 1 blz.

  Onderzoeksoutput: Poster

  • Actinium-225 100%
  • Single-Domain Antibodies 74%
  • Multiple Myeloma 48%
  • Radioisotopes 27%
  • Residual Neoplasm 11%
• 2020

  A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection.

  De Trez, C., Stijlemans, B., Bockstal, V., Cnops, J., Korf, H., Van Snick, J., Caljon, G., Muraille, E., Humphreys, I. R., Boon, L., Van Ginderachter, J. & Magez, S., 4 jun 2020, In : Frontiers in Immunology. 11, blz. 1085 15 blz., 1085.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Trypanosoma brucei brucei 100%
  • Interleukin-10 68%
  • Cytokines 47%
  • T-Lymphocytes 47%
  • Infection 36%
  4 Citaten (Scopus)

  58 Downloads (Pure)

• Anti-human PD-L1 Nanobody for Immuno-PET Imaging. IF(2019) 4,082: Validation of a Conjugation Strategy for Clinical Translation

  Bridoux, J., Broos, K., Lecocq, Q., Debie, P., Martin, C., Ballet, S., Raes, G., Neyt, S., Vanhove, C., Breckpot, K., Devoogdt, N., Caveliers, V., Keyaerts, M. & Xavier, C., okt 2020, In : Biomolecules. 10, 10, blz. 1-15 15 blz., 1388.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Single-Domain Antibodies 100%
  • Tumors 68%
  • Lysine 64%
  • 1,4,7-triazacyclononane-N,N',N''-triacetic acid 57%
  • Imaging techniques 50%
  9 Citaten (Scopus)

  33 Downloads (Pure)

• An Unbiased Immunization Strategy Results in the Identification of Enolase as a Potential Marker for Nanobody-Based Detection of Trypanosoma evansi

  Zeng, L., Pinto Torres, J. E., Goossens, J., Vertommen, D., Caljon, G., Sterckx, Y. & Magez, S., sep 2020, In : Vaccines. 8, 3, blz. 1-20 20 blz., 415.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Single-Domain Antibodies 100%
  • Trypanosoma 83%
  • Phosphopyruvate Hydratase 77%
  • Immunization 55%
  • New World Camelids 49%
  3 Citaten (Scopus)

  46 Downloads (Pure)

• Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections.

  Li, Z., Pinto Torres, J. E., Goossens, J., Stijlemans, B., Sterckx, Y. & Magez, S., 18 feb 2020, In : PLoS Neglected Tropical Diseases. 14, 2, 16 blz., e0008044.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Recombinases 100%
  • Trypanosoma 93%
  • DNA 41%
  • Infection 35%
  • Northern Asia 24%
  4 Citaten (Scopus)

  29 Downloads (Pure)

• Effects of non-invasive vagal nerve stimulation on radiation-induced inflammation and cancer prognosis

  Reijmen, E., de Mey, S., Van Damme, H., Gevaert, T., Collen, C., De Coster, L., De Couck, M., Laoui, D., Breckpot, K., De Grève, J., De Ridder, M., Gidron, Y. & Goyvaerts, C., 7 feb 2020.

  Onderzoeksoutput: Poster

  • Radiation-Induced Neoplasms 100%
  • Vagus Nerve Stimulation 88%
  • Myeloid-Derived Suppressor Cells 51%
  • Inflammation 39%
  • Radiotherapy 39%

• Establishment of a Standardized Vaccine Protocol for the Analysis of Protective Immune Responses During Experimental Trypanosome Infections in Mice

  Radwanska, M., Nguyen, H. T. T., Moon, S., Obishakin, E. & Magez, S., 28 mrt 2020, Trypanosomatids. Methods in Molecular Biology. Michels, P., Ginger, M. & Zilberstein, D. (redactie). NY: Humana Press, Vol. 2116. blz. 721-738 18 blz.

  Onderzoeksoutput: Chapter

  • trypanosomiasis 100%
  • vaccines 68%
  • immune response 66%
  • protocols 57%
  • mice 45%
  1 Citaat (Scopus)

• Functional impact of anti-PD-L1 treatment on specific lung (tumor) residing myeloid cell subsets

  De Ridder, K., Zuazo Ibarra, M., Awad, R. M., Neumann, J., De Vlaeminck, Y., Lecocq, Q., De Beck, L., Ertveldt, T., Locy, H., De Mey, W., Geeraerts, X., Brys, L., Laoui, D., Salmon, H., Breckpot, K. & Goyvaerts, C., 7 feb 2020.

  Onderzoeksoutput: Poster

• Hepatocarcinoma induces a tumor necrosis factor-dependent Kupffer cell death pathway that favors its proliferation upon partial hepatectomy

  Hastir, J-F., Delbauve, S., Larbanoix, L., Germanova, D., Goyvaerts, C., Allard, J., Laurent, S., Breckpot, K., Beschin, A., Guilliams, M. & Flamand, V., 16 okt 2020, In : Frontiers in Oncology. 10, 547013.

  Onderzoeksoutput: Article

  Open Access

  Bestand
  1 Citaat (Scopus)

  49 Downloads (Pure)

• Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection.

  Magez, S., Stijlemans, B., Korf, H., De Baetselier, P., Van Ginderachter, J. & De Trez, C., 3 feb 2020, In : PLoS Pathogens. 16, 2, 29 blz.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Interleukin-10 100%
  • Virulence 97%
  • Hepatocytes 93%
  • Infection 53%
  • B-Lymphocytes 51%
  31 Downloads (Pure)

• Identifying the variables that drive tamoxifen-independent CreERT2 recombination: implications for microglial fate mapping and gene deletions.

  Van Hove, H., Pombo Antunes, A. R., De Vlaminck, K., Scheyltjens, I., Van Ginderachter, J. & Movahedi, K., 3 mrt 2020, In : European Journal of Immunology. 50, 3, blz. 459-463 5 blz.

  Onderzoeksoutput: Article

  • Gene Deletion 100%
  • Tamoxifen 97%
  • Genetic Recombination 87%
  • Macrophages 64%
  • Cre recombinase 62%
  12 Citaten (Scopus)

• IFNγ signaling response in peripheral blood monocytes: A new prognostic biomarker for breast cancer?

  Deschoemaeker, S. & Laoui, D., 25 feb 2020, In : EBioMedicine. 53, blz. 102690 2 blz., 102690.

  Onderzoeksoutput: Article

  Open Access

  Bestand
  24 Downloads (Pure)

• Infections With Extracellular Trypanosomes Require Control by Efficient Innate Immune Mechanisms and Can Result in the Destruction of the Mammalian Humoral Immune System

  Magez, S., Pinto Torres, J. E., Obishakin, E. T. & Radwanska, M., 11 mrt 2020, In : Frontiers in Immunology. 11, 382, blz. 1-19 19 blz., 382.

  Onderzoeksoutput: Scientific review

  Open Access

  Bestand

  • Trypanosoma 100%
  • Immune System 63%
  • Antigenic Variation 47%
  • Infection 38%
  • Quorum Sensing 22%
  6 Citaten (Scopus)

  57 Downloads (Pure)

• Innate Immune Defense Mechanisms by Myeloid Cells That Hamper Cancer Immunotherapy: Innate Immune Defense Mechanisms by Myeloid Cells That Hamper Cancer Immunotherapy

  Lebegge, E., Arnouk, S. M., Bardet, P. M. R., Kiss, M., Raes, G. & Van Ginderachter, J. A., 9 jul 2020, In : Frontiers in Immunology. 11, 1395, blz. 1-14 14 blz., 1395.

  Onderzoeksoutput: Scientific review

  • Myeloid Cells 100%
  • Immunotherapy 87%
  • Neoplasms 31%
  • Antibody-Dependent Cell Cytotoxicity 22%
  • Cytophagocytosis 21%
  4 Citaten (Scopus)

• Intraoperative lymph node mapping using fluorescently-labeled mannose receptor-specific nanobodies

  Mateusiak, L., Debie, P., Declerck, N., Cyuzozo, C., van Willigen, D. M., Raes, G., Mottrie, A., van Leeuwen, F. W. B., De Sutter, P. & Hernot, S., 7 okt 2020.

  Onderzoeksoutput: Poster

• Isolation of Trypanosoma brucei brucei Infection-Derived Splenic Marginal Zone B Cells Based on CD1dHigh/B220High Surface Expression in a Two-Step MACS-FACS Approach

  Radwanska, M., Vereecke, N. & Magez, S., 28 mrt 2020, Trypanosomatids. Methods in Molecular Biology. Michels, P., Ginger, M. & Zilberstein, D. (redactie). NY: Humana Press, Vol. 2116. blz. 739-753

  Onderzoeksoutput: Chapter

  • Trypanosoma brucei brucei 100%
  • B-Lymphocytes 59%
  • Infection 36%
  • Cell Separation 15%
  • RNA Sequence Analysis 15%

• Non-canonical roles of connexins.

  Van Campenhout, R., Cooreman, A., Leroy, K., Rusiecka, O. M., Van Brantegem, P., Annaert, P., Muyldermans, S., Devoogdt, N., Cogliati, B., Kwak, B. R. & Vinken, M., jul 2020, In : Progress in Biophysics and Molecular Biology. 153, blz. 35-41 7 blz.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Connexins 100%
  • Gap Junctions 61%
  • Cell Death 60%
  • Growth 40%
  • Life Cycle Stages 28%
  6 Citaten (Scopus)

• Reshaping nanobodies for affinity purification on protein a

  Crauwels, M., Van Vaerenbergh, N., Kulaya, N. B., Vincke, C., D'Huyvetter, M., Devoogdt, N., Muyldermans, S. & Xavier, C., 25 jul 2020, In : New Biotechnology. 57, blz. 20-28 9 blz.

  Onderzoeksoutput: Article

  • Affinity chromatography 100%
  • Single-Domain Antibodies 78%
  • Antigens 70%
  • Purification 58%
  • Proteins 47%
  1 Citaat (Scopus)

• Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase

  Pinto Torres, J. E., Yuan, M., Goossens, J., Versées, W., Caljon, G., Michels, P. A., Walkinshaw, M. D., Magez, S. & Sterckx, Y. G-J., mrt 2020, In : Molecular and Biochemical Parasitology. 236, 111263.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • Trypanosoma congolense 100%
  • Pyruvate Kinase 78%
  • Trypanosoma 76%
  • Parasites 50%
  • Kinetics 43%
  11 Downloads (Pure)

• Systemic Reprogramming of Monocytes in Cancer

  Kiss, M., Caro, A. A., Raes, G. & Laoui, D., 17 sep 2020, In : Frontiers in Oncology. 10, 12 blz., 1399.

  Onderzoeksoutput: Article

  • Monocytes 100%
  • Neoplasms 39%
  • Immunotherapy 9%
  • Immunosuppressive Agents 9%
  • Immunity 9%
  7 Citaten (Scopus)

• T. brucei infections abrogate diverse plasma cell-mediated effector B cell responses, independently of their specificity, affinity and host genetic background.

  De Trez, C., Khan, S. & Magez, S., 1 jun 2020, In : PLoS Neglected Tropical Diseases. 14, 6, blz. 1-14 14 blz., e0008358.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • B-Lymphocyte Subsets 100%
  • Host Specificity 97%
  • Genetic Background 84%
  • Plasma Cells 79%
  • Trypanosoma 66%
  40 Downloads (Pure)

• Transient Multivalent Nanobody Targeting to CD206-Expressing Cells via PH-Degradable Nanogels.

  Scherger, M., Bolli, E., Pombo Antunes, A. R., Arnouk, S., Stickdorn, J., Van Driessche, A., Schild, H., Grabbe, S., De Geest, B., Van Ginderachter, J. & Nuhn, L., 1 okt 2020, In : Cells. 9, 10, 14 blz., 2222.

  Onderzoeksoutput: Article

  • NanoGel 100%
  • Single-Domain Antibodies 94%
  • Polymers 28%
  • Nanomedicine 13%
  • Fc Receptors 12%
  3 Citaten (Scopus)

• Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies

  Pombo Antunes, A. R., Scheyltjens, I., Duerinck, J., Neyns, B., Movahedi, K. & Van Ginderachter, J. A., 4 feb 2020, In : eLife. 9, 52176.

  Onderzoeksoutput: Article

  • Tumors 100%
  • Glioblastoma 96%
  • Neoplasms 31%
  • Refractory materials 30%
  • Macrophages 23%
  46 Citaten (Scopus)

• USP13 controls the stability of Aurora B impacting progression through the cell cycle

  Esposito, M., Akman, H. B., Giron, P., Ceregido, M. A., Schepers, R., Ramos Paez, L. C., La Monaca, E., De Greve, J., Coux, O., De Trez, C., Lindon, C. & Gutierrez, G. J., sep 2020, In : Oncogene. 39, 37, blz. 6009-6023 15 blz.

  Onderzoeksoutput: Article

  • Mitosis 100%
  • Interphase 88%
  • Cell Cycle 80%
  • Aurora Kinase B 39%
  • Anaphase-Promoting Complex-Cyclosome 37%
  2 Citaten (Scopus)

• Validation of miR-20a as a Tumor Suppressor Gene in Liver Carcinoma Using Hepatocyte-Specific Hyperactive piggyBac Transposons

  Tipanee, J., Di Matteo, M., Tulalamba, W., Samara-Kuko, E., Keirsse, J., Van Ginderachter, J. A., Chuah, M. K. & VandenDriessche, T., 6 mrt 2020, In : Molecular Therapy Nucleic Acids. 19, blz. 1309-1329 21 blz.

  Onderzoeksoutput: Article

  • Tumor Suppressor Genes 100%
  • Hepatocytes 85%
  • Hepatocellular Carcinoma 82%
  • Carcinoma 66%
  • Liver 51%
  4 Citaten (Scopus)
• 2019

  An innovative approach in the detection of Toxocara canis excretory/secretory antigens using specific nanobodies

  Morales-Yanez, F. J., Sariego, I., Vincke, C., Hassanzadeh-Ghassabeh, G., Polman, K. & Muyldermans, S., jul 2019, In : International Journal for Parasitology. 49, 8, blz. 635-645 11 blz.

  Onderzoeksoutput: Article

  Open Access

  • Toxocara canis TES-26 protein 100%
  • Single-Domain Antibodies 77%
  • Toxocara canis 76%
  • Enzyme-Linked Immunosorbent Assay 12%
  • Epitopes 7%
  8 Citaten (Scopus)

• A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

  Van Hove, H., Martens, L., Scheyltjens, I., De Vlaminck, K., Pombo Antunes, A. R., De Prijck, S., Vandamme, N., De Schepper, S., Van Isterdael, G., Scott, C. L., Aerts, J., Berx, G., Boeckxstaens, G. E., Vandenbroucke, R. E., Vereecke, L., Moechars, D., Guilliams, M., Van Ginderachter, J., Saeys, Y. & Movahedi, K., 6 mei 2019, In : Nature Neuroscience. 22, 6, blz. 1021-1035 15 blz.

  Onderzoeksoutput: Article

  • Atlases 100%
  • Macrophages 63%
  • Choroid Plexus 44%
  • Brain 44%
  • RNA Sequence Analysis 42%
  193 Citaten (Scopus)

• Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages

  Xavier, C., Blykers, A., Laoui, D., Bolli, E., Vaneycken, I., Bridoux, J., Baudhuin, H., Raes, G., Everaert, H., Movahedi, K., Van Ginderachter, J. A., Devoogdt, N., Caveliers, V., Lahoutte, T. & Keyaerts, M., 1 okt 2019, In : Molecular Imaging and Biology. 21, 5, blz. 898-906 9 blz.

  Onderzoeksoutput: Article

  Open Access

  Bestand

  • 1,4,7-triazacyclononane-N,N',N''-triacetic acid 100%
  • Single-Domain Antibodies 86%
  • Immunoglobulin Fragments 73%
  • Positron Emission Tomography Computed Tomography 63%
  • Macrophages 40%
  33 Citaten (Scopus)

  141 Downloads (Pure)

• Development of LAG-3 nanobodies as potent cancer imaging tracers

  Lecocq, Q., Awad, R. M., Zeven, K., De Vlaeminck, Y., De Mey, W., Debie, P., Puttemans, J., Goyvaerts, C., Raes, G., Keyaerts, M., Devoogdt, N. & Breckpot, K., 11 dec 2019.

  Onderzoeksoutput: Poster