Genetics Reproduction and Development

Onderzoeksoutput

Onderzoeksoutput per jaar 1970 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2030

• 82372 Citaties
• 135 h-index
• 1560 Article
• 280 Meeting abstract (Journal)
• 257 Poster
• 190 Meeting abstract (Book)
• 399 Meer
  • 79 Conference paper
  • 78 Chapter
  • 52 Other scientific journal contribution
  • 39 Editorial
  • 34 Unpublished abstract
  • 33 PhD Thesis
  • 31 Scientific review
  • 14 Letter
  • 13 Comment/debate
  • 7 Patent
  • 6 Book
  • 3 Other contribution
  • 3 Voordruk
  • 2 Foreword/postscript
  • 2 Other
  • 1 Other report
  • 1 Book/Film/Article review
  • 1 Special issue

Onderzoeksoutput per jaar

Onderzoeksoutput per jaar

Zoekresultaten

• 2025

  A first case of desmin-related myofibrillar myopathy due to inheritance from a confirmed mosaic asymptomatic carrier

  Uyttebroeck, S., Vlaeminck, J., De Schutter, E., Cordenier, A., Wellekens, S. A., Ströker, E., De Rooms, K., Helsen, C., Hes, F. J. & Giron, P., 14 mrt. 2025, (Unpublished). 1 blz.

  Onderzoeksoutput: Poster

• A novel liver organoid model using directed mutagenesis to study the oncogenic potential of human pluripotent stem cell-derived hepatocytes

  Huyghebaert, A., Al Delbany, D., Krivec, N., van Grunsven, L. A. & Spits, C., 11 apr. 2025, (Unpublished).

  Onderzoeksoutput: Poster

• Beyond BRAF^V600E - Revealing the Hidden Clinical Relevance of Uncharacterized BRAF Variants

  Vanisterbecq, D., Vandenplas, H., Olsen, C., Vlaeminck, J., Vaeyens, F., Helsen, C., Hes, F. J., Giron, P. & Maes, K., 17 jun. 2025, (Unpublished). 1 blz.

  Onderzoeksoutput: Poster

• Beyond Known Driver Variants - Unraveling variants of unknown significance in BRAF: A path to improve diagnosis, prognosis, and therapy in cancer patients

  Vanisterbecq, D., Vandenplas, H., Olsen, C., Vlaeminck, J., Vaeyens, F., Helsen, C., Hes, F. J., Giron, P. & Maes, K., 14 mrt. 2025, (Unpublished). 1 blz.

  Onderzoeksoutput: Poster

• Development of IgE autoantibodies in newborn with atopic dermatitis (DIANA)

  Belasri, H., Saerens, J., De Leye, H., Luttgens, P., Badloe, F., De Vriese, S., Gucciardo, L., Cools, F., Gies, I., Kortekaas Krohn, I. & Gutermuth, J., 25 feb. 2025, (Unpublished).

  Onderzoeksoutput: Poster

• Targeting MAT2A alters the methylation landscape and DNA damage response in Multiple Myeloma, revealing novel combination strategies.

  Van Hemelrijck, L. A., Wang, Y., Muylaert, C., Olsen, C., De Veirman, K., Vanderkerken, K., Menu, E. & De Bruyne, E., 7 feb. 2025. 1 blz.

  Onderzoeksoutput: Poster

• The effects of immune checkpoint inhibitors on adult male fertility using a mouse model

  De Beer, E., 2025, (Unpublished).

  Onderzoeksoutput: Poster

• Unraveling variants of unknown significance in BRAF: A path to improve diagnosis, prognosis, and therapy in cancer patients

  Vanisterbecq, D., Vandenplas, H., Olsen, C., Vlaeminck, J., Vaeyens, F., Helsen, C., Hes, F. J., Giron, P. & Maes, K., 2025, (Unpublished).

  Onderzoeksoutput: Poster
• 2024

  Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells.

  Al Delbany, D., Myrthe Mampay , Adhithya Narayanan Srinivasan, Krivec, N., Huyghebaert, A., Lei, Y., Sermon, K., Movahedi, K. & Spits, C., 29 nov. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• A new clinically relevant classification of seminiferous tubules in Klinefelter Syndrome patients based on the karyotype of the Sertoli cells.

  Gül, S., Vloeberghs, V., Gies, I. & Goossens, E., 3 jul. 2024.

  Onderzoeksoutput: Poster

• Characterization of patients stopping GH therapy for childhood-onset growth hormone deficiency in Belgium - Luxemburg

  Boutsen, L., Thomas, M., Staels, W., Lysy, P. A., Becker, M., Rochtus, A., Boros, E., De Waele, K., Dotrement, H., Parent, A-S., Klink, D., Chivu, O., Massa, G., Beckers, D., Depoorter, S., Reynaert, N., Logghe, K. & De Schepper, J., 14 mei 2024.

  Onderzoeksoutput: Poster

• COL13A1 connects glycogen accumulation with the phenotype in Pompe disease

  Uyttebroeck, S., Vo Ngoc, D. T. L., Osei, R., Dequeker, B., Seneca, S., Hes, F. J. & Gheldof, A., 12 apr. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Combing deep shotgun metagenomic sequencing and culturomics for in-depth characterization of a potential endometrial microbiome

  Rahou, I., Vanstokstraeten, R., Allonsius, C., De Boeck, I., T, V. R., S, W., Mackens, S., Demuyser, T. & Lebeer, S., 2024.

  Onderzoeksoutput: Poster

• Comprehensive (Epi)Genetic Tumor Characterization and Disease Follow-Up in Multiple Myeloma Using Blood-Derived Cell-Free DNA

  Heestermans, R., Olsen, C., Succari, J., Ameli, S., Janssen, T., De Becker, A., Vande Broek, I., Bakkus, M. H. C., Schots, R., De Bruyne, E. & Van Riet, I., 5 nov. 2024.

  Onderzoeksoutput: Poster

• Comprehensive alpha, beta, and delta cell transcriptomics reveal an association of cellular aging with MHC class I upregulation

  Staels, W., 7 aug. 2024.

  Onderzoeksoutput: Poster

  Bestand
  20 Downloads (Pure)

• Development and Validation of a Patient-Reported Outcome Measure for patients with Inherited Cardiac Conditions: Integrating Genetic Well-Being

  Van Pottelberghe, S., 6 dec. 2024.

  Onderzoeksoutput: Poster

• Development of a human stem cell-based in vitro model to assess toxicity hazards induced by thyroid hormone system disruptors during the early phases of liver development

  Marchandise, L. D. P., Baert, Y., Rodrigues, R., Poulsen, R., Hansen, M., Rogiers, V. & Vanhaecke, T., 3 jun. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Development of a novel Patient-Reported Outcome Measure (PROM) for adults with an Inherited Cardiac Condition (ICC)

  Van Pottelberghe, S., 2024.

  Onderzoeksoutput: Poster

• Development of IgE Autoantibodies in Newborns with Atopic dermatitis: DIANA Birth cohort

  De Leye, H., Saerens, J., Belasri, H., Badloe, F., Gucciardo, L., Cools, F., Gies, I., Kortekaas Krohn, I. & Gutermuth, J., 13 jun. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Dose-Dependent Effects of Murine Anti-Thymocyte Globulin (mATG) on Type 1 Diabetes (T1D) Development in Non-Obese Diabetic (NOD) Mice

  Degroote, L., Wouters, A., Lemaitre, P., Mathieu, C., Gysemans, C., De Leu, N. & Staels, W., 7 nov. 2024.

  Onderzoeksoutput: Poster

• Elevated high sensitivity C-reactive Protein concentrations in Belgian children and adolescents living with overweight or obesity.

  Donckerwolcke, K. E., Mol, T., Nauwynck, E., Vanbesien, J., Staels, W., De Schepper, J. & Gies, I., mrt. 2024.

  Onderzoeksoutput: Poster

• Expression of CTLA-4, PD-1, and PD-L1 proteins by testicular cells

  Ntemou, E., Delgouffe, E. & Goossens, E., 2024, (Unpublished).

  Onderzoeksoutput: Poster

• From bleeding to diagnosis : unveiling a case of epithelioid hemangioendothelioma

  Vannerom, C. G., Geens, W., Marcelis, W., Van Gestel, F., Van der Straeten, R., van Tussenbroek, F., Brock, S., Duerinck, J. & Bruneau, M., 19 apr. 2024.

  Onderzoeksoutput: Poster

• Liver organoids to study if aneuploidy primes human pluripotent stem-cell derived hepatocytes for oncogenic transformation

  Huyghebaert, A., Al Delbany, D., Ghosh, M., Kazemzadeh Dastjerd, M., Krivec, N., van Grunsven, L. A. & Spits, C., 8 apr. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Liver organoids to study if aneuploidy primes human pluripotent stem-cell derived hepatocytes for oncogenic transformation

  Huyghebaert, A., Al Delbany, D., Ghosh, M., Kazemzadeh Dastjerd, M., Krivec, N., van Grunsven, L. A. & Spits, C., 29 nov. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Matrix-Free 3D in Vitro Follicle Culture Exhibits Enhanced Oocyte Meiotic and Developmental Competence Compared to Hydrogel Encapsulation in Mice

  Zisiadi, A., Billooye, K. & Anckaert, E., 2024. 1 blz.

  Onderzoeksoutput: Poster

• Oocyte/zygote/embryo maturation arrest: a functional and clinical study expanding the phenotype of NOBOX variants

  Van Der Kelen, A., Uyttebroeck, S., Van de Voorde, S. R., Segers, I., Vlaeminck, J., Verdyck, P., Dequeker, B., Giron, P., Verpoest, W., Hes, F. J. & Gheldof, A., 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Oocyte/zygote/embryo maturation arrest: expanding the phenotype of NOBOX variants 

  Van Der Kelen, A., Uyttebroeck, S., Van de Voorde, S. R., Segers, I., Vlaeminck, J., Dequeker, B., Giron, P., Verpoest, W., Hes, F. J., Verdyck, P. & Gheldof, A., 7 jul. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Parsing Genetic and Autoimmune Etiology in Premature Ovarian Insufficiency

  Nauwynck, E., De Schepper, J., De Vos, M. & Staels, W., 14 mrt. 2024.

  Onderzoeksoutput: Poster

• Polymorphic lymphoproliferative disorder in an immunocompromised patient mimicking multifocal glioblastoma

  Billen, M., Lefesvre, P., Paquet, J. & Brock, S., 2024.

  Onderzoeksoutput: Poster

• PW 31. Learning points from a cross-sectional cohort study in individuals with pathogenic variants in FLNA

  Rijckmans, E., De Strooper, L. P., Keymolen, K., Jansen, A. & Stouffs, K., mrt. 2024.

  Onderzoeksoutput: Poster

• Relief from endoplasmic reticulum stress drives ß-cell proliferation

  Bourgeois, S., Van Mulders, A., Heremans, Y., Leuckx, G., Kancheva, D., Scheyltjens, I., Movahedi, K., Willems, L., Coenen, S., Degroote, L., Pierreux, J., Yi, X., Cnop, M., Heimberg, H., De Leu, N. & Staels, W., 18 jun. 2024.

  Onderzoeksoutput: Poster

• REPURPOSING TRANSGENDER TESTICULAR TISSUE: ANDROGENIC TESTICULAR ORGANOIDS FOR HIGH-THROUGHPUT APPLICATIONS

  Madureira Silva, S., Richer, G., Errico, A., Papageorgiou, K., Vanhaecke, T., Goossens, E. & Baert, Y., 3 jun. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Respiratory distress in a young child? Not always infectious!

  Rijckmans, E., Vergaelen, K. & Smeets, N. M. G., mrt. 2024.

  Onderzoeksoutput: Poster

• SALL3 regulates the pluripotency networks in human pluripotent stem cells

  Duong, C. M., Lei, Y., Krivec, N., Huyghebaert, A., Al Delbany, D. & Spits, C., 2024. 1 blz.

  Onderzoeksoutput: Poster

• Single-Cell RNA-Seq Characterization of PCOS Oocytes collected from small antral follicles: Insights for IVM Optimization

  Akin, N., Saucedo-Cuevas, L., Galvao, A., Cava Cami, B., Van Ranst, H., De Vos, M., Kelsey, G. & Anckaert, E., 2024. 1 blz.

  Onderzoeksoutput: Poster

• Spatial Characterization of B7H3 Expression in PDAC reveals increased Expression in Basal-like Tumor Ducts and αSMA-positive Stromal Cells

  De Man, V., Michiels, E., Messaoudi, N., Olsen, C., Giron, P. & Rooman, I., 18 apr. 2024.

  Onderzoeksoutput: Poster

• Spatial Characterization of CD276 (B7H3) Expression in PDAC reveals increased Expression in Basal-like Tumor Ducts and αSMA-positive Stromal Cells

  De Man, V., Michiels, E., Messaoudi, N., Olsen, C., Giron, P. & Rooman, I., 23 okt. 2024.

  Onderzoeksoutput: Poster

• Study of digital cortical bone and its determinants in boys and adolescents with Klinefelter syndrome

  Nauwynck, E., Hickmann, M., Ernst, C., Willekens, I., Anckaert, E., Vanbesien, J., Staels, W., De Schepper, J. & Gies, I., 11 okt. 2024.

  Onderzoeksoutput: Poster

• Termination of pregnancy for foetal abnormalities (TOPFA) en reproductive decisions

  Slegers, I., 2024.

  Onderzoeksoutput: Poster

• Testicular organoids: a potential model to study the impact of endocrine-disrupting chemicals on steroidogenesis.

  Papageorgiou, K., Madureira Silva, S., Goossens, E., Vanhaecke, T. & Baert, Y., 19 sep. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• The testicular organoid as a model to study the impact of endocrine-disrupting chemicals on steroidogenesis.

  Papageorgiou, K., Madureira Silva, S., Errico, A., Vanhaecke, T., Goossens, E. & Baert, Y., 11 mrt. 2024, (Unpublished) blz. 1-1. 1 blz.

  Onderzoeksoutput: Poster

  • endocrine-disrupting chemicals 100%
  • steroidogenesis 94%
  • Leydig cells 78%
  • testosterone 57%
  • estrogens 44%

• Transient congenital hypothyroidism in a newborn with congenital goiter and compound heterozygosity for thyroglobulin

  Nauwynck, E., Gheldof, A., Vanden Eynde, N. E. M., Vanbesien, J., Depoorter, S., Oosterlynck, C., Staels, W., Gies, I. & De Schepper, J., 16 nov. 2024.

  Onderzoeksoutput: Poster

• Treatment responses in an adolescent male with combined Camurati-Engelmann disease and Crohn's Disease

  Nauwynck, E., Smeets, N. M. G., Huysentruyt, K., Scholliers, A., Dimitrov, B., Andrzejewski, A. C., De Wachter, E. & De Schepper, J., 22 jun. 2024.

  Onderzoeksoutput: Poster

• Two unrelated cases of prenatal Shwachman-Diamond syndrome: a diagnosis complicated by a rare clinical presentation and a pseudogene

  Vanden Eynde, N. E. M., Slegers, I., Vantroys, E., Symoens, S., Done, E., Leus, A., Brock, S., Keymolen, K., Hes, F. J., Dimitrov, B. & Van Berkel, K., 12 apr. 2024, (Unpublished).

  Onderzoeksoutput: Poster
• 2023

  Aneuploid human embryonic stem cells mis-specify during retinal pigment epithelium differentiation but retain their selective advantage

  Huyghebaert, A., Lei, Y., Couvreu De Deckersberg, E. & Spits, C., 24 nov. 2023, (Unpublished).

  Onderzoeksoutput: Poster

• ANEUPLOIDY AS A FIRST GENETIC HIT THAT ENHANCES THE TUMORIGENIC CAPACITY OF DIFFERENTIATED HUMAN PLURIPOTENT STEM CELLS

  Al Delbany, D., Ghosh, M., Krivec, N., Couvreu De Deckersberg, E., Lei, Y., Sermon, K. & Spits, C., dec. 2023, (Unpublished).

  Onderzoeksoutput: Poster

• A novel FZR1 variant causing developmental: and epileptical encephalopathy

  Bansagi, B. K., Scalais, E., Stouffs, K., de Ravel, T., Keymolen, K., Hes, F. J. & Dimitrov, B., 2023.

  Onderzoeksoutput: Poster

• A systematic review and evidence assessment of monogenic gene-disease relationships in human female infertility and differences in sex development

  Van Der Kelen, A., feb. 2023.

  Onderzoeksoutput: Poster

• CHARACTERISTICS OF OBESE PRESCHOOLERS REFERRED TO A TERTIARY OBESITY MANAGEMENT CENTER IN BELGIUM

  Nauwynck, E., Van Himbeeck, K., Staels, W., Vanbesien, J., Verheyden, S., Rutteman, B., De Schepper, J. & Gies, I., 3 feb. 2023.

  Onderzoeksoutput: Poster