Projecten per jaar
Organisatieprofiel
Organisation profile
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Translationele Levercelbiology actief is. Deze onderwerplabels komen uit het werk van de leden van deze organisatie. Samen vormen ze een unieke vingerafdruk.
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
Profielen
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IOF3035: B-LIVER 2.0 (Brusselse Alliantie voor Leveronderzoek & Valorisatie)
Vanhaecke, T., van Grunsven, L., De Kock, J., Vinken, M., Reynaert, H. & Van Goethem, F.
1/01/25 → 31/12/29
Project: Toegepast
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FWOTM1257: CATCH - CAR-T cel immunotherapie tegen Chronische leverziekte en Hepatocellulair carcinoom
De Wolf, R., van Grunsven, L. & Breckpot, K.
1/11/24 → 31/10/28
Project: Fundamenteel
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HERC66: 3D-CELLMAP: Onthullen van complexe celinteracties in weefsels door middel van 3D super-resolutie proteïne multiplex beeldvorming.
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamenteel
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OZR4233: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB - KU Leuven, KIMPS Laurens
20/10/23 → 19/10/27
Project: Fundamenteel
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EU667: Imaging Ageing Endothelium at the nanoscale - Doctorates
1/10/23 → 30/09/27
Project: Fundamenteel
Onderzoeksoutput
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A novel liver organoid model using directed mutagenesis to study the oncogenic potential of human pluripotent stem cell-derived hepatocytes
Huyghebaert, A., Al Delbany, D., Krivec, N., van Grunsven, L. A. & Spits, C., 11 apr 2025, (Unpublished).Onderzoeksoutput: Poster
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Hepatic stellate cell single cell atlas reveals a highly similar activation process across liver disease aetiologies
Merens, V., Knetemann, E., Gürbüz, E., De Smet, V., Messaoudi, N., Reynaert, H., Verhulst, S. & van Grunsven, L. A., jan 2025, In: JHEP reports. 7, 1, blz. 1-12 12 blz., 101223.Onderzoeksoutput: Article › peer review
Open AccessBestand1 Citaat (Scopus)9 Downloads (Pure) -
An opto-acousto-fluidic microchip for efficient Raman spectroscopy of microparticles in aqueous environment
Lotfi Choobbari, M., Vandermotten, M., Chalyan, T., Bihi, I., Gelin, P. P., De Malsche, W., Meulebroeck, W., van Grunsven, L. A., Thienpont, H. & Ottevaere, P. D. I. H., 1 nov 2024, In: Sensors and Actuators. B, Chemical. 418, blz. 1-10 10 blz., 136300.Onderzoeksoutput: Article › peer review
Open AccessBestand9 Downloads (Pure) -
Early detection of liver fibrosis through hepatic stellate cell activation monitoring using Raman spectroscopy and machine learning
Vandermotten, M., Knetemann, E., Chalyan, T., Meulebroeck, W., van Grunsven, L. A. & Ottevaere, P. D. I. H., 2024, Early detection of liver fibrosis through hepatic stellate cell activation monitoring using Raman spectroscopy and machine learning. Popp, J. & Gergely, C. (redactie). SPIE, Vol. 13006. blz. 1-6 6 blz. 1300603. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 13006).Onderzoeksoutput: Conference paper › Research
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Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
Krivec, N., Couvreu De Deckersberg, E., Lei, Y., Al Delbany, D., Regin, M., Verhulst, S., van Grunsven, L. A., Sermon, K. & Spits, C., 21 nov 2024, In: Cell Death and Disease. 15, 14 blz., 852.Onderzoeksoutput: Article › peer review
Open Access
Activiteiten
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Drug-induced liver injury in biopsy-scaled Precision-Cut Liver Slices.
Milan Lobo (Speaker) & Leo van Grunsven (Contributor)
13 feb 2025Activiteit: Talk or presentation at a conference
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OZR ZAP selection (Evenement)
Aldo Scafoglieri (Contributor), Eva Swinnen (Contributor), Koen Putman (Chair), Debby Mangelings (Contributor) & Leo van Grunsven (Contributor)
8 jun 2022Activiteit: Membership of peer-review panel or committee
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Multicellular primary mouse liver spheroids for DILI, NAFLD, NASH and fibrosis studies.
Laura Cools (Speaker), Elise Van Os (Speaker), Nathalie Eysackers (Contributor), Ayla Smout (Contributor), Stefaan Verhulst (Contributor), Hendrik Reynaert (Contributor), Inge Mannaerts (Contributor) & Leo van Grunsven (Contributor)
28 sep 2021Activiteit: Talk or presentation at a conference
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Multicellular primary mouse liver spheroids for DILI, NAFLD, NASH and fibrosis studies.
Laura Cools (Speaker), Elise Van Os (Speaker), Nathalie Eysackers (Contributor), Ayla Smout (Contributor), Stefaan Verhulst (Contributor), Hendrik Reynaert (Contributor), Inge Mannaerts (Contributor) & Leo van Grunsven (Contributor)
24 jun 2021Activiteit: Talk or presentation at a conference
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LSECs in chronic liver disease- Willy Gepts, UZ brussel
Elise Van Os (Recipient) & Leo van Grunsven (Contributor)
1 jan 2021 → 1 jan 2022Activiteit: Written proposal
Datasets
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Human iPSC-derived liver co-culture spheroids to model liver fibrosis
Kazemzadeh Dastjerd, M. (Creator), van Grunsven, L. (Creator) & Cools, L. (Creator), Zenodo, 20 feb 2024
DOI: 10.5281/zenodo.10684185, https://zenodo.org/records/10684185
Dataset
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Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity
Laoui, D. (Creator), Hamouda, A. E. I. (Creator), Filtjens, J. (Creator), Brabants, E. (Creator), Kancheva, D. (Creator), Debraekeleer, A. (Creator), Brughmans, J. (Creator), Jacobs, L. (Creator), Bardet, P. (Creator), Knetemann, E. (Creator), Lefesvre, P. (Creator), Allonsius, L. (Creator), Gontsarik, M. (Creator), Varela, I. (Creator), Crabbé, M. (Creator), Clappaert, E. (Creator), Cappellesso, F. (Creator), Caro, A. A. (Creator), Gordún Peiró, A. (Creator), Fredericq, L. (Creator), Hadadi, E. (Creator), Senti, M. E. (Creator), Schiffelers, R. (Creator), van Grunsven, L. (Creator), Nana, F. A. (Creator), De Geest, B. (Creator), Deschoemaeker, S. (Creator), De Koker, S. (Creator) & Lambolez, F. (Creator), NCBI Gene Expression Omnibus, 12 nov 2024
Dataset