Projecten per jaar
Organisatieprofiel
Organisation profile
De Visual & Spatial Tissue Analysis (VSTA) kernfaciliteit biedt in situ detectie van DNA-afwijkingen, multiplex RNA-expressie, puntmutaties (DNA/RNA/Basescope) en multiplex eiwitexpressie (immunokleuring, Ultivue) met whole-slide imaging (brightfield/fluorescentie) en geavanceerde digitale beeldanalyse.
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
Profielen
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Ilse Rooman
- Vrije Universiteit Brussel
- Basis (bio)-medische wetenschappen - Extra Functie (Rector, vice rector, decaan, vakgroepvoorzitter, Hoofd van een onderzoeksgroep)
- Translational Oncology Research Center
- Visual and Spatial Tissue Analysis
Persoon: Onderzoeker, Professor
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HERC66: 3D-CELLMAP: Onthullen van complexe celinteracties in weefsels door middel van 3D super-resolutie proteïne multiplex beeldvorming.
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamenteel
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BRGRD73: POC 2023: Library sceening and hit validation for pancreatic cancer
Ballet, S., De Neve, J., Rooman, I. & Versées, W.
1/01/24 → 31/03/25
Project: Policy Based
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OZR3804: Verlenging van het PhD-traject vanwege Covid-19 (OZR budget)
Pierson, J., Tindemans, K., De Leu, N., Claeys, P., Coene, G., Simón, L., Raats, T., Hes, F. J., Loisen, J., Orban, A., van Heur, B., De Graeve, I., Goderis, S., Verfaillie, K., Christiaens, J., Tindemans, K., Anckaert, E., Meyer, T., Dumortier, E., Anckaert, E., Rooman, I., Cohen, J. & Gutermuth, J.
7/10/21 → 30/09/24
Project: Fundamenteel
Onderzoeksoutput
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Drug Repurposing in Pancreatic Cancer: A Multi-Stakeholder Perspective to Improve Treatment Options for Pancreatic Cancer Patients
Hewitt, E., Bouche, G., Alencar, A. C., Bigelsen, S. J., Radu, R., Stoyanova-Beninska, V., Carrato, A., Valsecchi, F., Soler Cantón, A., van der Meer, H. G., García Bermejo, M. L., Budillon, A., Cardone, L., Rooman, I., Platteeuw, H., Baijet, J. & Fuchs, C., 1 mrt 2025, In: Cancer management and research. 17, blz. 429-440 12 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand5 Downloads (Pure) -
ROBO1 Drives Gemcitabine Resistance in Pancreatic Cancer
Mader, S., Rodriguez Aznar, E. & Rooman, I., 2025, (Unpublished).Onderzoeksoutput: Poster
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Abstract 3378: Acinar cell susceptibility for tumor development in the pancreas: Targeting the critical regulators for therapy
Pan, Z., Van den Bossche, J-L., Rodriguez Aznar, E., Janssen, P., Lara, O., Ates, G., Massie, A., De Paep, D. L., Houbracken, I., Mambretti, M. & Rooman, I., 15 mrt 2024, In: Cancer Research. 84, 6_supplement, 1 blz., 3378.Onderzoeksoutput: Meeting abstract (Journal)
Open Access -
Acinar cell susceptibility for tumor development in the pancreas: targeting the critical regulators for therapy
Pan, Z., Van den Bossche, J-L., Rodriguez Aznar, E., Janssen, P., Lara, O., Ates, G., Massie, A., De Paep, D. L., Houbracken, I., Mambretti, M. & Rooman, I., apr 2024, (Accepted/In press).Onderzoeksoutput: Poster
Activiteiten
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Spatial transcriptomic analysis reveals PTGES as a conserved potential therapeutic target for basal cells in Pancreatic Ductal Adenocarcinoma
Jan-Lars Van den Bossche (Speaker), Ilse Rooman (Contributor) & Melissa Van der Vliet (Contributor)
2024Activiteit: Talk or presentation at a conference
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Wetenschappelijk Raad van Stichting tegen Kanker (Externe Organisatie)
Ilse Rooman (Chair)
2024 → …Activiteit: Membership of peer-review panel or committee
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ambassador Team Hope Stichting Tegen Kanker (Externe Organisatie)
Ilse Rooman (Member)
2024 → …Activiteit: Work on advisory panels for social, community and cultural engagement
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Visual and Spatial Tissue Analysis (VSTA) At Your Service
Ilse Rooman (Speaker)
21 mrt 2023Activiteit: Talk or presentation at a workshop/seminar
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High resolution and quantitative intra-ductal spatial analysis reveals phenotypic and functional diversification in pancreatic cancer
Ellis Michiels (Speaker), Ilse Rooman (Contributor), Nouredin Messaoudi (Contributor), Hediel Madhloum (Contributor), Silke Christophe Van Lint (Contributor), Philippe Giron (Contributor), Catharina Olsen (Contributor), Nelson Dusetti (Contributor) & Jean-Luc Van Laethem (Contributor)
30 apr 2023Activiteit: Talk or presentation at a conference
Uitrusting
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ERA platform: Extended RNA Analysis platform - version 2.0.
Ilse Rooman (Infrastructure coordinator)
Visual and Spatial Tissue AnalysisUitrusting/faciliteit: no e-resource/single sited
Datasets
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Pancreatic acinar cell fate relies on system xc- to prevent ferroptosis during stress
Pan, Z. (Creator), Mambretti, M. (Researcher) & Rooman, I. (Project Leader), Gene Expression Omnibus (GEO), 7 aug 2023
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE240106
Dataset
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Dataset for 'High-resolution and quantitative spatial analysis reveal intra-ductal phenotypic and functional diversification in pancreatic cancer'
Michiels, E. (Creator) & Rooman, I. (Creator), VUB Institutional Data Repository, 19 mrt 2025
Dataset
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Zhaolong Pan dataset 'Pancreatic acinar cell fate'
Rooman, I. (Creator) & Pan, Z. (Creator), VUB Institutional Data Repository, 2024
Dataset
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Dataset Marco Mambretti FWOAL931 & FWOODYS12
Rooman, I. (Creator) & Mambretti, M. (Creator), VUB Institutional Data Repository, 19 mrt 2025
Dataset