Visual and Spatial Tissue Analysis

Onderzoeksoutput

Onderzoeksoutput per jaar 2003 2024 2025

• 24 Citaties
• 2 h-index
• 29 Poster
• 8 Article
• 5 PhD Thesis
• 3 Meeting abstract (Journal)
• 4 Meer
  • 2 Scientific review
  • 1 Meeting abstract (Book)
  • 1 Voordruk

Onderzoeksoutput per jaar

Onderzoeksoutput per jaar

Zoekresultaten

• 2025

  ROBO1 Drives Gemcitabine Resistance in Pancreatic Cancer

  Mader, S., Rodriguez Aznar, E. & Rooman, I., 2025, (Unpublished).

  Onderzoeksoutput: Poster
• 2024

  Acinar cell susceptibility for tumor development in the pancreas: targeting the critical regulators for therapy

  Pan, Z., Van den Bossche, J-L., Rodriguez Aznar, E., Janssen, P., Lara, O., Ates, G., Massie, A., De Paep, D. L., Houbracken, I., Mambretti, M. & Rooman, I., apr. 2024, (Accepted/In press).

  Onderzoeksoutput: Poster

• Macrophage impact on cellular plasticity in pancreatic basal cells

  Van Lint, S., Van den Bossche, J-L., Van der Vliet, M., Baldan, J. & Rooman, I., 21 nov. 2024.

  Onderzoeksoutput: Poster

• ROBO1 Drives Gemcitabine Resistance in Pancreatic Cancer

  Mader, S., Rooman, I., Rodriguez Aznar, E., Soubeyran, P., Dusetti, N. & Bousquet Vaysse, C., 17 jun. 2024, (Unpublished).

  Onderzoeksoutput: Poster

  • gemcitabine 100%
  • Pancreatic Neoplasms 84%
  • Adenocarcinoma 70%
  • Heterografts 20%
  • 130-nm albumin-bound paclitaxel 17%

• ROBO1 Drives Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

  Mader, S., Soubeyran, P., Dusetti, N., Bousquet Vaysse, C., Rodriguez Aznar, E. & Rooman, I., 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Spatial Characterization of B7H3 Expression in PDAC reveals increased Expression in Basal-like Tumor Ducts and αSMA-positive Stromal Cells

  De Man, V., Michiels, E., Messaoudi, N., Olsen, C., Giron, P. & Rooman, I., 18 apr. 2024.

  Onderzoeksoutput: Poster

• Spatial Characterization of CD276 (B7H3) Expression in PDAC reveals increased Expression in Basal-like Tumor Ducts and αSMA-positive Stromal Cells

  De Man, V., Michiels, E., Messaoudi, N., Olsen, C., Giron, P. & Rooman, I., 23 okt. 2024.

  Onderzoeksoutput: Poster

• Spatial co-localization of macrophages and basal cells in the pancreas

  Van Lint, S., Van den Bossche, J-L., Van der Vliet, M., Baldan, J. & Rooman, I., 23 okt. 2024.

  Onderzoeksoutput: Poster

• Spatial transcriptomic analysis of human Pancreatic Basal Cells reveals PTGES as a potential target for the Basal-Like subtype of Pancreatic Ductal Adenocarcinoma.

  Van den Bossche, J-L., Van der Vliet, M., Coolens, K., Michiels, E., Houbracken, I., Baldan, J. & Rooman, I., 18 apr. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Spatial transcriptomic analysis reveals PTGES as a conserved potential therapeutic target for basal cells in Pancreatic Ductal Adenocarcinoma.

  Van der Vliet, M., Van den Bossche, J-L. & Rooman, I., 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Spatial transcriptomic and single cell sequencing data reveals PTGES as a conserved potential therapeutic target for basal cells in pancreatic cancer.

  Van der Vliet, M., Van den Bossche, J-L., Coolens, K., Van Lint, S., Michiels, E., Houbracken, I., Baldan, J. & Rooman, I., okt. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Spatial transcriptomic and single cell sequencing data reveals PTGES as a conserved potential therapeutic target for basal cells in pancreatic cancer.

  Van der Vliet, M. & Rooman, I., 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Unravel acinar cell subpopulation with propensity for cancer initiation

  Baldan, J., Scheele, C., Jacquemin, P. & Rooman, I., 23 okt. 2024, (Unpublished).

  Onderzoeksoutput: Poster

• Unravel proliferative acinar cell subpopulation with propensity for cancer initiation.

  Baldan, J., Scheele, C., Jacquemin, P. & Rooman, I., 29 nov. 2024, (Unpublished).

  Onderzoeksoutput: Poster
• 2023

  Systemic deletion of xCT in mice attenuates peripheral inflammation and inflammation-related mood disturbances in a pancreatic cancer model

  Lara, O., Janssen, P., Mambretti, M., De Pauw, L., Ates, G., Mackens, L., De Munck, J., Beckers, P., Sato, H., De Ridder, M., Aerts, J., Hermans, E., Rooman, I. & Massie, A., 21 apr. 2023, (Unpublished).

  Onderzoeksoutput: Poster

• Systemic deletion of xCT in mice attenuates peripheral inflammation and inflammation-related mood disturbances in a pancreatic cancer model

  Lara, O., Janssen, P., Mambretti, M., De Pauw, L., Ates, G., Mackens, L., De Munck, J., Beckers, P., Sato, H., De Ridder, M., Aerts, J., Hermans, E., Rooman, I. & Massie, A., 6 jun. 2023, (Unpublished).

  Onderzoeksoutput: Poster

• System xc- (xCT) prevents ferroptosis in pancreatic acinar cells as a first step in acinar-to-ductal metaplasia

  Pan, Z., Van den Bossche, J-L., Rodriguez Aznar, E., Janssen, P., Lara, O., Massie, A., De Paep, D. L., Houbracken, I., Mambretti, M. & Rooman, I., nov. 2023, (Unpublished).

  Onderzoeksoutput: Poster

  Bestand
  117 Downloads (Pure)

• System xc- prevents ferroptosis in pancreatic acinar cells as a first step in acinar-to-ductal metaplasia

  Pan, Z. & Rooman, I., apr. 2023, (Unpublished).

  Onderzoeksoutput: Poster

• Tackling pancreatic cancer from different angles: compartmentalized role of xCT in supporting tumor growth and inflammation-related comorbidities in mice

  Lara, O., Janssen, P., Mambretti, M., De Pauw, L., Ates, G., Mackens, L., De Munck, J., Walckiers, J., Pan, Z., Beckers, P., Espinet, E., Sato, H., De Ridder, M., Marks, D. L., Barbé, K., Aerts, J., Hermans, E., Rooman, I. & Massie, A., 13 nov. 2023, (Unpublished).

  Onderzoeksoutput: Poster
• 2022

  Spatial heterogeneity of mutant KRAS expression in the context of pancreatic cancer subtypes

  Michiels, E., Messaoudi, N., Rooman, I., Giron, P., Olsen, C., Lefesvre, P. & Frederix, K., 29 sep. 2022.

  Onderzoeksoutput: Poster

• Spatial heterogeneity of mutant KRAS expression in the context of pancreatic cancer subtypes

  Michiels, E., Rooman, I., Messaoudi, N., Giron, P., Olsen, C., Frederix, K. & Lefesvre, P., 6 nov. 2022.

  Onderzoeksoutput: Poster

• Spatial Heterogeneity of Mutant KRAS Expression in the Context of Pancreatic Cancer Subtypes

  Rooman, I., 5 nov. 2022.

  Onderzoeksoutput: Poster

• Targeting system xc- in a mouse pancreatic cancer model reduces tumor growth, neuroinflammation and mood disturbances

  Lara, O., Janssen, P., Mambretti, M., De Pauw, L., Ates, G., Mackens, L., De Munck, J., Beckers, P., Njemini, R., Sato, H., Aerts, J., Hermans, E., Rooman, I. & Massie, A., 9 mei 2022, (Unpublished).

  Onderzoeksoutput: Poster
• 2021

  Discovery and 3D imaging of deltaNp63-expressing cells in the human pancreatic duct that share characteristics with an aggressive molecular subtype of pancreatic cancer: poster and video abstract

  Rooman, I., 5 mei 2021.

  Onderzoeksoutput: Poster

• Discovery and 3D imaging of deltaNp63-expressing cells in the human pancreatic duct that share characteristics with the aggressive molecular subtype of pancreatic cancer: Poster Discussion Session for Top Abstracts

  Rooman, I., 9 jun. 2021.

  Onderzoeksoutput: Poster

• Setting up a PDXO platform for pancreatic cancer with spatial omics characterization

  Michiels, E. & Rooman, I., 5 okt. 2021.

  Onderzoeksoutput: Poster

• Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization

  Michiels, E. & Rooman, I., 21 sep. 2021.

  Onderzoeksoutput: Poster
• 2019

  In vivo investigation of a potential regulator of pancreatic acinar dedifferentiation

  Michiels, E., Backx, E. & Rooman, I., 25 jun. 2019, (Unpublished).

  Onderzoeksoutput: Poster

  Bestand
  47 Downloads (Pure)
• 2018

  Drug Repurposing as a Source of Innovative Therapies in Pancreatic Cancer

  Pantziarka, P., Capistrano, R., Bouche, G. & Rooman, I., 2018.

  Onderzoeksoutput: Poster

  • Drug Repositioning 100%
  • Investigational Therapies 89%
  • Pancreatic Neoplasms 68%
  • Pharmaceutical Preparations 30%
  • plerixafor octahydrochloride 28%