Projecten per jaar
Vingerafdruk
Verdiep u in de onderzoeksgebieden waarop Anfien Huyghebaert actief is. Deze onderwerplabels komen uit het werk van deze persoon. Samen vormen ze een unieke vingerafdruk.
- 1 Soortgelijke profielen
Samenwerkingen en hoofdonderzoeksgebieden uit de afgelopen vijf jaar
Recente externe samenwerking op landen-/regioniveau. Duik in de details door op de stippen te klikken of
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FWOTM1310: Het gebruik van lever organoïden om te bestuderen of aneuploïdie humane pluripotente stamcelafgeleide hepatocyten voorbereidt voor oncogene transformatie
Huyghebaert, A. (Mandataris), Spits, C. (Administrative Promotor) & Al Delbany, D. (CoI (Co-Promotor))
1/11/25 → 31/10/29
Project: Fundamenteel
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OZR4351: OZR opvangmandaat aspirant Anfien Huyghebaert
Spits, C. (Administrative Promotor) & Huyghebaert, A. (Mandataris)
1/11/24 → 31/10/25
Project: Fundamenteel
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1q gain bypasses the selective barrier against aneuploidy in RPE differentiation via wild-type co-culture rescue
Couvreu De Deckersberg, E., Lei, Y., Krivec, N., Huyghebaert, A., Duong, M. C., Janssens, C., Regin, M., Tsuiko, O., Movahedi, K., Verhulst, S., van Grunsven, L. A., Sermon, K., Al Delbany, D. & Spits, C., 25 nov. 2025, In: Nature Communications. 16, 1, 15 blz., 11627.Onderzoeksoutput: Article › peer review
Open AccessBestand -
Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells
Al Delbany, D., Mampay, M., Srinivasan, A. N., Krivec, N., Huyghebaert, A., Movahedi, K. & Spits, C., 12 jun. 2025.Onderzoeksoutput: Poster
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Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells
Al Delbany, D., Mampay, M., Srinivasan, A. N., Krivec, N., Huyghebaert, A., Movahedi, K. & Spits, C., 11 apr. 2025, (Unpublished).Onderzoeksoutput: Poster
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Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells
Al Delbany, D., Mampay, M., Srinivasan, A. N., Krivec, N., Huyghebaert, A., Duong, M. C., Sarkar, A., Brock, S., Movahedi, K. & Spits, C., 28 nov. 2025.Onderzoeksoutput: Poster
Open Access -
A novel liver organoid model using directed mutagenesis to study the oncogenic potential of human pluripotent stem cell-derived hepatocytes
Huyghebaert, A., Al Delbany, D., Krivec, N., van Grunsven, L. A. & Spits, C., 11 apr. 2025, (Unpublished).Onderzoeksoutput: Poster
Datasets
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De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Spits, C. (Creator), Al Delbany, D. (Creator), Ghosh, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Regin, M. (Creator), Duong, C. M. (Creator), Lei, Y. (Creator), Sermon, K. (Creator) & Olsen, C. (Creator), VUB Institutional Data Repository, 15 okt. 2025
Dataset
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Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells
Spits, C. (Creator), Lei, Y. (Creator), Regin, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Couvreu De Deckersberg, E. (Creator), Sermon, K. (Creator), Al Delbany, D. (Creator), Duong, C. M. (Creator) & Janssens, C. (Creator), VUB Institutional Data Repository, 10 okt. 2025
Dataset
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Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
Spits, C. (Creator), Regin, M. (Creator), Lei, Y. (Creator), Couvreu De Deckersberg, E. (Creator), Janssens, C. (Creator), Huyghebaert, A. (Creator), Guns, Y. (Creator), Verheyen, G. (Creator), Van De Velde, H. (Creator) & Sermon, K. (Creator), VUB Institutional Data Repository, 10 okt. 2025
Dataset
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Liver organoids to study if aneuploidy primes human pluripotent stem-cell derived hepatocytes for oncogenic transformation
Huyghebaert, A. (Participant), Al Delbany, D. (Supervisor) & Spits, C. (Supervisor)
1 nov. 2025 → 31 okt. 2029Activiteit: Written proposal
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SALL3 drives selective growth advantage and modulates pluripotency in hPSCs with chromosome 18q loss
Duong, C. M. (Presenter), Krivec, N. (Contributor), Al Delbany, D. (Contributor), Huyghebaert, A. (Contributor) & Spits, C. (Contributor)
28 nov. 2025Activiteit: Talk or presentation at a conference
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A comparative analysis of three different trophectoderm biopsy techniques and their impact on apoptosis, necrosis and chromosome analysis
Janssens, C. (Presenter), Tryfonos, M. (Contributor), Fernandez Gallardo, E. (Contributor), Regin, M. (Contributor), Huyghebaert, A. (Contributor), Duong, C. M. (Contributor), Vandermonde, A. (Contributor), Broekaert, W. (Contributor), Verdoodt, P. (Contributor), Van De Velde, H. (Contributor), Sermon, K. (Contributor) & De Munck, N. (Contributor)
8 apr. 2025Activiteit: Talk or presentation at a conference
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Trophectoderm biopsy: a comparative analysis of three different techniques on human blastocysts and their impact on apoptosis, necrosis, chromosome analysis and blastocyst recovery
Janssens, C. (Presenter), Tryfonos, M. (Contributor), Fernandez Gallardo, E. (Contributor), Regin, M. (Contributor), Huyghebaert, A. (Contributor), Duong, C. M. (Contributor), Ghesquiere, B. (Contributor), Vandermonde, A. (Contributor), Broekaert, W. (Speaker), Verdoodt, P. (Contributor), Tournaye, H. (Contributor), Van De Velde, H. (Contributor), Sermon, K. (Contributor) & De Munck, N. (Contributor)
1 jul. 2025Activiteit: Talk or presentation at a conference
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Liver organoids to study if aneuploidy primes human pluripotent stem-cell derived hepatocytes foroncogenic transformation
Huyghebaert, A. (Contributor)
1 mrt. 2024Activiteit: Written proposal
Scriptie
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Assessing tumorigenicity in HESCs carrying Chromosomal abnormalities in brain and liver organoid models
Ghijselings, K. ((PhD) Student), Al Delbany, D. (Co-promotor), Huyghebaert, A. (Co-promotor) & Spits, C. (Promotor), 29 mei 2026Scriptie/Masterproef: Master's Thesis