Onderzoeksoutput per jaar
Onderzoeksoutput per jaar
- 17 resultaten
Zoekresultaten
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2024
Allosteric nanobodies to study the interactions between SOS1 and RAS
Fischer, B., Uchański, T., Sheryazdanova, A., Gonzalez, S., Volkov, A. N., Brosens, E., Zögg, T., Kalichuk, V., Ballet, S., Versées, W., Sablina, A. A., Pardon, E., Wohlkönig, A. & Steyaert, J., 23 jul 2024, In: Nature Communications. 15, 1, 8 blz., 6214.Onderzoeksoutput: Article › peer review
Open AccessBestand2 Downloads (Pure) -
2023
Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS
Van Holsbeeck, K., Fischer, B., Gonzalez, S., Gadais, C., Versées, W., Martins, J., Martin, C., Wohlkonig, A., Steyaert, J. & Ballet, S., 12 jun 2023, In: Angewandte Chemie International Edition. 62, 24, blz. 1-6 6 blz., e202219095.Onderzoeksoutput: Article › peer review
Open AccessBestand3 Citaten (Scopus)7 Downloads (Pure) -
2022
Downsizing Nanobodies: Towards CDR3 Loop Mimetics Modulating Intracellular Protein-Protein Interactions
Van Holsbeeck, K., Fischer, B., Gonzalez, S., Gadais, C., Versées, W., Martins, J. C., Martin, C., Wohlkönig, A., Steyaert, J. & Ballet, S., 4 nov 2022, Proceedings of the 36th European and the 12th International Peptide Symposium. Lebl, M. (redactie). European Peptide Society , blz. 141-142Onderzoeksoutput: Conference paper
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Nanobody CDR3 mimetics enhance SOS1-catalyzed nucleotide exchange on RAS
Van Holsbeeck, K., Fischer, B., Gonzalez, S., Gadais, C., Versées, W., Martins, J. C., Martin, C., Wohlkönig, A., Steyaert, J. & Ballet, S., 2022.Onderzoeksoutput: Voordruk
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Nanobody exchange chromatography
Steyaert, J., Pardon, E., Wohlkönig, A., Zögg, T., Kalichuk, V., De Keyser, P. & Fischer, B., 2022, Octrooi Nr. EP4077372Onderzoeksoutput: Patent
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2021
Constructing and purifying megabodies starting from individual nanobody sequences
Uchański, T., Fischer, B., Kalichuk, V., Wohlkönig, A., Zögg, T., Pardon, E. & Steyaert, J., 7 jan 2021, 11 blz.Onderzoeksoutput: Other contribution
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Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
Uchański, T., Masiulis, S., Fischer, B., Kalichuk, V., López-Sánchez, U., Zarkadas, E., Weckener, M., Sente, A., Ward, P., Wohlkönig, A., Zögg, T., Remaut, H., Naismith, J. H., Nury, H., Vranken, W., Aricescu, A. R., Pardon, E. & Steyaert, J., jan 2021, In: Nature Methods. 18, 1, blz. 60-68 9 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand76 Citaten (Scopus)304 Downloads (Pure) -
2019
An improved yeast surface display platform for the screening of nanobody immune libraries
Uchański, T., Zögg, T., Yin, J., Yuan, D., Wohlkönig, A., Fischer, B., Rosenbaum, D. M., Kobilka, B. K., Pardon, E. & Steyaert, J., 23 jan 2019, In: Scientific Reports - Nature. 9, 1, blz. 1-12 12 blz., 382.Onderzoeksoutput: Article › peer review
Open AccessBestand67 Citaten (Scopus)636 Downloads (Pure) -
Compounds for treatment of intractable epilepsy and doors syndrome
Verstreken, P., Lüthy, K., Versées, W., Fischer, B. & Paesmans, J., 2019, Octrooi Nr. EP3503880Onderzoeksoutput: Patent
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TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model
Lüthy, K., Mei, D., Fischer, B., De Fusco, M., Swerts, J., Paesmans, J., Parrini, E., Lubarr, N., Meijer, I. A., Mackenzie, K. M., Lee, W-T., Cittaro, D., Aridon, P., Schoovaerts, N., Versées, W., Verstreken, P., Casari, G. & Guerrini, R., 1 aug 2019, In: Brain. 142, 8, blz. 2319-2335 17 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand45 Citaten (Scopus)144 Downloads (Pure) -
2018
Compounds for treatment of intractable epilepsy and doors syndrome
Verstreken, P., Lüthy, K., Versées, W., Fischer, B. & Paesmans, J., 2018, Octrooi Nr. WO2018041812Onderzoeksoutput: Patent
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Revealing the function of TBC1D24 mutations in epilepsy and related neurological diseases
Paesmans, J., Versees, W., Fischer, B., Verstreken, P. & Lüthy, K., 8 feb 2018, (Unpublished).Onderzoeksoutput: Poster
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TBC1D24-skywalker has a lipid-binding pocket mutated in epilepsy and required for synaptic function
Paesmans, J., Versees, W., Fischer, B., Verstreken, P. & Lüthy, K., 9 mei 2018, (Unpublished).Onderzoeksoutput: Poster
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Yeast and Cancer: Common Mechanism Underlying Activation of Ras by Glycolytic Flux
Peeters, K., Van Leemputte, F., Fischer, B., Haesen, D., Ward, V., Bonini, B., Quezada, H., Bravo, C., Versees, W., Janssens, V., Tompa, P. & Thevelein, J. M., apr 2018, FASEB J.. 1 redactie Vol. 32. blz. NA 1 blz.Onderzoeksoutput: Conference paper
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2017
Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras
Peeters, K., Van Leemputte, F., Fischer, B., Bonini, B. M., Quezada, H., Tsytlonok, M., Haesen, D., Vanthienen, W., Bernardes, N., Gonzalez-Blas, C. B., Janssens, V., Tompa, P., Versées, W. & Thevelein, J. M., 13 okt 2017, In: Nature Communications. 8, 1, 15 blz., 922.Onderzoeksoutput: Article › peer review
Open Access129 Citaten (Scopus) -
TBC1D24-skywalker has a lipid-binding pocket mutated in epilepsy and required for synaptic function.
Paesmans, J., Fischer, B., Lüthy, K., De Koninck, C., Maes, I., Swerts, J., Kuenen, S., Uytterhoeven, V., Verstreken, P. & Versees, W., 17 jul 2017.Onderzoeksoutput: Poster
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2016
Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function
Fischer, B., Lüthy, K., Paesmans, J., De Koninck, C., Maes, I., Swerts, J., Kuenen, S., Uytterhoeven, V., Verstreken, P. & Versées, W., nov 2016, In: Nature Structural and Molecular Biology. 23, 11, blz. 965-973 9 blz.Onderzoeksoutput: Article › peer review
Open AccessBestand48 Citaten (Scopus)175 Downloads (Pure)