Projecten per jaar
Persoonlijk profiel
Expertise
Bart Neyns obtained his MD (1992) and PhD (2001) from the Vrije Universiteit Brussel (VUB), Brussels. Dr Neyns held a Research Fellowship supported by the National Fund for Scientific Research (NFWO), at the Laboratory of Medical Oncology, VUB (1992–1996). In 1996, he began furthering his training in Internal Medicine and Medical Oncology, at the same institute, obtaining his Specialist Degree in 1999. Dr Neyns subsequently became a Resident at the Department of Internal Medicine/Medical Oncology, VUB (1999–2002). In 2009, Dr Neyns specialized in Medical Oncology. During 2002–2012 and 2012-2019, he was appointed respectively as Head of Clinic and Head of Division at the Department of Medical Oncology, UZ Brussel, before being appointed to his current position as Head of Department at the same department, in May 2019. He currently holds an additional parallel position as Clinical Professor at the Faculty of Medicine and Pharmacy, VUB (since 2007); between 2010 and 2018 he served as a Dermato-Oncology Consultant at the Erasme Hospital Université Libre de Bruxelles (ULB), Brussels. Dr Neyns is the member of seven national and international scientific societies including, the Belgian Medical Society of Medical Oncology ESMO, and ASCO. He has been the recipient of several competitive research grants, and has considerable clinical trial experience as a Principal Investigator for more than fifteen academia sponsored clinical trials for patients with advanced melanoma, glioma and colorectal cancer; including clinical trials with a proprietary autologous dendritic cell therapy (TriMixDC) and first-in-human phase I clinical trials with intratumoral injection of autologous myeloid dendritic cells. Dr Neyns has an extensive publication record as the (co-)author of over hundred forty primary manuscripts published in peer review medical journals (incl. N Engl J Med, Lancet Oncol, and the J Clin Oncol), and has been invited speaker at several international congresses. His current research interests broadly include the immune- and targeted therapy of melanoma and the treatment of patients with malignant glioma with a strong emphasis on conducting academia sponsored trials.
Vingerafdruk
- 1 Soortgelijke profielen
Netwerk
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FWOTM1132: Gezondheidsgerelateerde levenskwaliteit, psychosociale gevolgen en neurocognitieve functie bij overlevenden van uitgezaaide kanker behandeld met immunotherapie, gevolgd door integratieve neurocognitieve remediëringtherapie
Neyns, B., Rogiers, A. & Vanlaer, N.
1/11/22 → 31/10/26
Project: Fundamenteel
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OZR3588: Financiering FWO Hercules: ERA platform: Uitgebreid RNA Analyse platform - versie 2.0
Rooman, I., Bouwens, L., Heimberg, H., Neyns, B., Vranken, W., Vanhaecke, T., Massie, A., van Grunsven, L., De Bruyne, E., De Bundel, D., Forsyth, R., Breckpot, K., Van Dooren, S., De Kock, J., Njemini, R. & Laoui, D.
1/05/20 → 30/04/24
Project: Fundamenteel
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SRP62: SRP-Groeifinanciering: Single-domain antibody fragment (SdAb)-based TArgeted Radionuclide Therapy: STaRT programme
Keyaerts, M., D'Huyvetter, M. & Neyns, B.
1/03/19 → 29/02/24
Project: Fundamenteel
Onderzoeksoutput
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Assessment of Retinal Pigment Epithelium Alterations and Chorioretinal Vascular Network Analyses in Patients under Treatment with BRAF/MEK Inhibitor for Different Malignancies: A Pilot Study
Fasolino, G., Awada, G., Moschetta, L., Koulalis, J. S., Neyns, B., Verhelst, B., Van Elderen, P., Nelis, P., de Lichtbuer, P. C., Cools, W. & Ten Tusscher, M., 3 feb 2023, In: Journal of clinical medicine. 12, 3, 1214.Onderzoeksoutput: Article › peer review
Open Access -
Auto-immune hemolytic anemia and hemophagocytic lymphohistiocytosis as immune-related adverse event in patients with metastatic melanoma and concurrent chronic lymphocytic leukemia: a case series and literature review
Dirven, I., Vander Mijnsbrugge, A-S., Mignon, S., Tijtgat, J., Kint, N. & Neyns, B., 28 apr 2023, In: Melanoma Research.Onderzoeksoutput: Article › peer review
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Current "state of the art" on dendritic cell-based cancer vaccines in melanoma
Schwarze, J. K., Geeraerts, X., Tuyaerts, S. & Neyns, B., 1 mrt 2023, In: Current Opinion in Oncology. 35, 2, blz. 87-93 7 blz.Onderzoeksoutput: Article › peer review
Open Access3 Citaten (Scopus) -
Low-Dose Bevacizumab for the Treatment of Focal Radiation Necrosis of the Brain (fRNB): A Single-Center Case Series
Tijtgat, J., Calliauw, E., Dirven, I., Vounckx, M., Kamel, R., Vanbinst, A. M., Everaert, H., Seynaeve, L., Berge, D. V. D., Duerinck, J. & Neyns, B., 29 apr 2023, In: Cancers (Basel). 15, 9, 2560.Onderzoeksoutput: Article › peer review
Open Access -
Neurocognitive Functioning in Metastatic Cancer Survivors Treated With Immune Checkpoint Blockade: First Results of A Single Center Cohort Study
Vanlaer, N., Kyndt, D., Van Eycken, S., Tijtgat, J., Kessels, J., Dirven, I., Vounckx, M., Neyns, B. & Rogiers, A., 31 jan 2023.Onderzoeksoutput: Poster
Datasets
Prijzen
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Best Poster Award
Awada, Gil (Recipient), Özdemir, Ibrahim (Recipient), Schwarze, Julia Katharina (Recipient), Daeninck, E. (Recipient), Gondry, Odrade (Recipient), Jansen, Y. (Recipient), Seremet, T. (Recipient), Keyaerts, Marleen (Recipient), Everaert, Hendrik (Recipient) & Neyns, Bart (Recipient), 15 dec 2018
Prijs: Prize (including medals and awards)
Activiteiten
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A phase I clinical trial on intracranial administration of autologous myeloid dendritic cells (myDC) in combination with ipilimumab and nivolumab in patients with recurrent glioblastoma (rGB).
Wietse Geens (Speaker), Julia Katharina Schwarze (Contributor), Cleo Bertels (Contributor), Jens Tijtgat (Contributor), Gil Awada (Contributor), F Vaeyens (Contributor), Louise Cras (Contributor), Anne Vanbinst (Contributor), Hendrik Everaert (Contributor), Alex Michotte (Contributor), Toon Janssen (Contributor), Ben Caljon (Contributor), Thomas Cauwenbergh (Contributor), Michaël Bruneau (Contributor), Ramses Forsyth (Contributor), Sandra Tuyaerts (Contributor), Bart Neyns (Contributor) & Johnny Duerinck (Contributor)
26 mrt 2022Activiteit: Talk or presentation at a conference
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Prognostic value of 0-(2-[18F]-fluoroethyl)-L-tyrosine PET in patients with recurrent glioblastoma.
Wietse Geens (Speaker), Stephanie Du Four (Contributor), S VAN LAERE (Contributor), Julia Katharina Schwarze (Contributor), Gil Awada (Contributor), Michaël Bruneau (Contributor), Jens Tijtgat (Contributor), Hendrik Everaert (Contributor), Bart Neyns (Contributor) & Johnny Duerinck (Contributor)
26 mrt 2022Activiteit: Talk or presentation at a conference
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A phase I clinical trial on intracranial administration of autologous myeloid dendritic cells (myDC) in combination with ipilimumab and nivolumab in patients with recurrent glioblastoma (rGB).
Wietse Geens (Speaker), Julia Katharina Schwarze (Contributor), Cleo Bertels (Contributor), Jens Tijtgat (Contributor), Gil Awada (Contributor), F Vaeyens (Contributor), Louise Cras (Contributor), Anne Vanbinst (Contributor), Hendrik Everaert (Contributor), Alex Michotte (Contributor), Toon Janssen (Contributor), Ben Caljon (Contributor), Thomas Cauwenbergh (Contributor), Michaël Bruneau (Contributor), Ramses Forsyth (Contributor) & Bart Neyns (Contributor)
26 mrt 2022Activiteit: Talk or presentation at a conference
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Intracranial administration of CTLA-4 and PD-1 immune checkpoint blocking monoclonal antibodies in recurrent glioblastoma (rGB): a multi-cohort adaptive phase I clinical trial
Julia Katharina Schwarze (Speaker), Wietse Geens (Contributor), Jens Tijtgat (Contributor), Gil Awada (Contributor), Anne-Marie Van Binst (Contributor), Hendrik Everaert (Contributor), Laura Seynaeve (Contributor), Alex Michotte (Contributor), Michaël Bruneau (Contributor), I VAN RIET (Contributor), Sandra Tuyaerts (Contributor), Johnny Duerinck (Contributor) & Bart Neyns (Contributor)
16 sep 2021 → 21 sep 2021Activiteit: Talk or presentation at a conference
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A phase I clinical trial on intratumoral injection of autologous CD1c (BDCA-1)+ / CD141 (BDCA-3)+ myeloid dendritic cells in combination with talimogene laherparepvec (T-VEC) in patients with advanced pretreated melanoma
Julia Katharina Schwarze (Presenter), Jens Tijtgat (Contributor), Gil Awada (Contributor), Louise Cras (Contributor), Inès Dufait (Contributor), Ramses Forsyth (Contributor), Sandra Tuyaerts (Contributor) & Bart Neyns (Contributor)
17 sep 2021Activiteit: Talk or presentation at a conference
Scriptie
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FDG PET/CT parameters voor de voorspelling van algemene en progressievrije overleving na pembrolizumab-behandeling bij melanoompatienten
Auteur: Özdemir, I., Keyaerts, M., Neyns, B. & Everaert, H., 20 jun 2018Scriptie/Masterproef: Master's Thesis
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Retrospectieve analyse van de waarde van totaal metabool tumor volume op FDG-PET/CT bij melanoompatiënten behandeld met Pembrolizumab
Auteur: Calliauw, L., Keyaerts, M., Neyns, B., Everaert, H. & Goethals, L., 13 jun 2019Scriptie/Masterproef: Master's Thesis